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readcluster

Kai Schmid edited this page Mar 25, 2019 · 16 revisions

The readcluster() function performs a gene set enrichment analyses with the help of clusterProfiler. Also it generates a new file for each new cluster which contains all modalities and all edges which can be found in the matrix before the reduction.

readcluster(clustermember = block_member.csv, matrix = matrix, minclustersize = 9, minp.adjust = 0.01)

Arguments of the readcluster() function.

argument function default
clustermember blockmember.csv file from Graph.py
matrix matrix from calcscorematrix()
minclustersize minimum size of the cluster to be given to the enrichment analyses 9
minp.adjust minimum p.adjust for the enrichment analyses 0.01

Gene set enrichment

The request against the KEGG database generates a PDF file for all genes of the graph and for the genes of every found cluster. It contains a dotplot, goplot, barplot and a cnetplot (shown below).

cnetplot