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| INTEGRIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/INTEGRIN_BINDING ADAMTS13 FCER2 EDIL3 ADAM2 TGFBI ANGPTL3 SYK ADAM9 COL4A3 ADAM11 TNXB ICAM4 ACTN4 EGFL6 ADAM23 ICAM2 DMP1 ICAM3 ACTN1 ACTN2 ACTN3 ECM2 COL16A1 THY1 VWF ADAMTS8 ERBB2IP FBLN5 DST ADAMTS5 | |
| CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC9A7 SLC9A6 SLC9A5 SLC9A3 SLC9A2 ATP2B1 ATP2B3 CUL5 ATP2B4 KCNK7 KCNK6 KCNK5 CHRNA4 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 SLC12A7 SLC12A9 SCN2B ABCB11 SCN2A NNT RHCG ATP2C1 RYR3 RYR1 RYR2 SURF1 KCNMB3 KCNMB4 ORAI1 SCN1B CACNB1 CACNB2 CACNB3 CACNB4 KCNJ3 KCNMB1 KCNMB2 KCNJ1 ATP6V0C SLC11A2 SLC31A2 SLC31A1 TRPC1 TRPC4 TRPC3 TRPC5 KCNK1 KCNK3 KCNK4 KCNJ5 KCNJ4 KCNJ6 ATP2A2 ATP2A3 ATP2A1 CHRNB4 CHRNB3 CHRNB2 CHRND CHRNE SLC9A1 KCNK17 KCNH1 KCNJ15 COX11 ATP6V0E1 SLC20A1 SLC15A1 SLC20A2 COX10 SLC15A2 TRPV1 KCNJ10 KCNIP2 KCNJ12 KCNJ14 KCNK10 FXN SLC22A4 TRPV5 SLC22A3 TRPV6 SLC22A2 SLC22A1 COX15 KCNG2 ATP4A ATP4B SLC3A2 CACNG5 CACNG4 CYB5A CACNG2 CACNG1 ATP6V1C1 KCNA10 SCN11A KCNH2 KCNH3 KCNH4 CLDN16 SHROOM2 COX7A2L KCNE1 PKD2 KCNE2 HTR3A HTR3B SLC8A1 COX7A1 ITPR3 TRAPPC10 ITPR1 ITPR2 ACCN1 ACCN4 ABCC8 KCNC1 KCNC4 KCNC3 SLC22A13 SLC6A2 SLC22A14 COX5A COX5B MS4A2 SLC4A4 KCND3 SLC34A3 SLC40A1 KCNA2 COX7B KCNA1 KCNA4 KCNA3 KCNA6 ATP6V1B2 KCNA5 KCNS3 KCNS1 GAR1 SCN9A SLC30A4 SLC30A5 SLC30A3 CACNA2D1 KCNB2 COX8A CACNA1S P2RX4 P2RX7 SLC4A11 P2RX1 P2RX3 CACNA1G CACNA1H SLC13A2 CACNA1E CACNA1F SLC13A4 CACNA1C CACNA1D CACNA1A CACNA1B SLC5A3 SLC5A2 UQCRC1 SLC5A1 KCNQ5 KCNQ3 CCT8L2 SCN7A KCNQ2 KCNQ1 COX4I2 COX4I1 TRPM2 TRPM1 UQCRH CCS SCNN1G SCNN1B SCN5A SLC39A2 SCNN1D SLC12A1 NOX5 SLC12A2 SLC12A3 SLC12A4 SLC10A2 RHAG SLC10A1 SLC17A7 KCNN4 SLC17A5 SLC6A9 SLC17A3 SLC6A8 SLC17A4 KCNN3 SLC6A5 KCNN2 SLC17A2 SLC6A6 SCN4B SLC5A6 SLC5A7 SCN4A | |
| MAP_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MAP_KINASE_ACTIVITY MAPK1 MAPK12 MAPK13 MAPK14 NLK MAPK4 MAPK15 MAPK9 MAPK11 MAPK8 MAPK10 MAPK7 | |
| TRANSLATION_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSLATION_REGULATOR_ACTIVITY TUFM ABCF1 EIF2C1 COPS5 EIF5A EIF2A PAIP2B EIF3C PET112 EIF3D EIF3B EIF3E EIF3F EEF2K DAZL PABPC1 EIF3J EIF2B2 EIF2B3 EIF2B4 SAMD4A EIF2B5 DAZ1 PAIP2 PAIP1 EIF2S3 GTF2H3 EIF2B1 GTF2H2 BOLL EIF4G1 EIF4B EIF4G2 EIF4E GSPT1 MTRF1 EIF4H EIF2S1 EIF4A2 EIF2S2 GSPT2 | |
| HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES XRCC5 FHIT ATP1B1 ATP1B3 ATP1B2 XRCC6 RAB1A ATP2B1 DDX17 ATP2B3 DDX18 ATP2B4 DHX38 DIRAS3 RAB28 VPS4B GNG3 RAB27B RAB27A GTPBP2 GTPBP4 OPA1 ABCB11 RAN NCF1 EIF2S3 NUDT10 MYH7 NUDT11 MYH6 MYH9 RND2 RND3 RFC3 ATP2C1 SMARCAL1 AGAP2 RAB13 GNAI3 ENPP1 GNAI2 GNAI1 ENPP2 ENPP3 MYO9B ARF6 ARF5 ATP6V0C THTPA RAC2 RAC3 RAC1 DHX8 DHX9 ATP11B RAB7L1 ABCG1 ABCG2 PPA1 RERG GNGT1 ARF1 ATP2A2 ATP2A3 ARF3 ARF4 ATP2A1 CCT8 RHEB RAD54B ABCF1 GNAZ ATP6V0E1 RAB5B RAB5C RAB6A TOP2A RAP2A RBBP4 ATP4A ATP4B RAB4A TTF2 RAD51 ATP6V1C1 EIF4A3 GNAL GNB2 GNAQ GNB1 RAB5A RUVBL2 GNAS RUVBL1 GNB3 DOLPP1 ARL4D RASD1 ARL4C ARL4A RAB3A RAB3B RAB3D SKIV2L WRNIP1 GNG11 INO80 RAB11B ABCD3 ABCD4 RAB2A UPF1 ATP1A3 ATP1A4 ATP1A1 ATP1A2 TRIM23 RAB31 RAB30 RAB35 GNG10 RAB22A ABCC3 KIF20B PPP2R4 ABCC1 ABCC2 DNM1 ABCC6 GNA13 SEPT5 SEPT4 GNA14 GNA15 RAB9A GNA11 SNRNP200 GNA12 EIF5 RRAD TAPBP DDX23 DDX25 RRAS DDX21 DDX20 MX2 NUDT2 NUDT1 NUDT4 MYO3A NUDT3 EFTUD2 NUDT5 PICK1 CLPX SMARCA5 SMARCA1 SEPT9 DDX39A MYL6 ABCA8 RAB7A FXYD2 MRAS ARFRP1 KATNB1 ABCA2 ATP6V1B2 ABCA3 RRAGC DDX3X KATNA1 ENTPD4 RAB6C DDX43 MYO1E PIF1 ABCB7 RAB33A ATP7A PSMC6 DDX56 PSMC5 PSMC4 VCP PSMC1 RAP1A DDX54 DUT ATP7B MYH10 RSF1 PEX6 CDC42 ARHGAP5 PEX1 RASL10A RHOA ACYP2 ATP8B1 ACYP1 RHOB RHOC RHOD RHOG ARL1 RALBP1 G3BP1 RECQL KIF1B BPTF RRAS2 ERCC8 ERCC6 CHD2 CHD1 TGM3 ERCC3 CHD4 CHD3 MSH6 DNM1L GNAO1 MSH2 RABL2A RABL2B GSPT1 | |
| MRNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/MRNA_BINDING ZFP36 HNRNPAB PABPC4 FMR1 RPL35 GRSF1 SSB ELAVL2 ELAVL4 PURB SLBP AUH ZFP36L1 HNRPDL EIF4A3 PARN TIA1 SERBP1 EIF4A1 SLU7 PABPC3 PABPC1 CPSF1 | |
| PROTEIN_PHOSPHATASE_TYPE_2A_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_PHOSPHATASE_TYPE_2A_REGULATOR_ACTIVITY PPP2R1A PPP2R3B PPME1 PPP2R3A PPP2R5B PPP2R5A PPP2R5D SET IGBP1 PPP2R4 PPP2R5E EIF2AK2 PPP2R2B PPP2R2A | |
| ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ATP1B1 SLC44A1 SLC9A7 SLC9A6 SLC44A2 ATP1B3 AQP9 SLC9A5 ATP1B2 SLC6A2 SLC9A3 SLC6A3 SLC9A2 SLC6A4 SLC7A8 SLC7A9 SLC22A11 SLC7A4 SLC7A5 SLC7A6 TAPBP ATP2B1 ATP2B3 ATP2B4 SLC25A22 SLC4A4 SLC4A3 SLC12A7 SLC12A9 ABCB11 PDPN SLC34A3 SEC61B ATP2C1 ABCA8 FXYD2 SLC38A3 ATP6V1B2 ABCA3 ATP6V0C SERINC1 SLC6A14 ATP11B ABCB7 ANKH ABCG1 ABCG2 ATP7A SLC25A12 SLC25A11 SLC25A13 ATP2A2 SLC7A2 ATP2A3 ATP2A1 SLC13A2 SLC13A4 SLC25A15 ATP7B SLC9A1 SLC5A3 ABCF1 SLC5A2 ATP6V0E1 SLC20A1 SLC15A1 SLC20A2 SLC15A2 SLC5A1 SLC1A4 SLC1A5 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC22A4 ATP8B1 SLC22A3 SLC1A1 SLC43A1 OCA2 ATP4A ATP4B SLC22A7 SLC3A2 SLC7A10 SLC3A1 SLC7A11 ATP6V1C1 ABCD3 ABCD4 SLC12A1 SLC12A2 SLC12A3 SLC12A4 ATP1A3 ATP1A4 ATP1A1 ATP1A2 SLC10A2 SLC10A1 SLC17A7 SLC17A5 SLC6A9 SLC16A7 SLC17A3 SLC17A4 SLC6A8 SLC6A5 SLC17A2 SLC6A6 SLCO1B1 ABCC3 SLC18A2 SLC18A3 ABCC1 SLC5A6 SLC18A1 ABCC2 SLC5A7 CTNS ABCC6 | |
| GLUTAMATE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GLUTAMATE_RECEPTOR_ACTIVITY GRIK1 GRIK2 GRIK3 GRIK4 GRIN2A GABBR1 GRIK5 GABBR2 GRM1 GRM5 GRM4 GRM3 GRM2 GRIA2 GRIN2B GRM8 GRIN2C GRIA1 GRM7 GRM6 | |
| ACID_AMINO_ACID_LIGASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ACID_AMINO_ACID_LIGASE_ACTIVITY DZIP3 RNF217 MYLIP GSS WWP2 WWP1 FBXO22 ANAPC2 ANAPC5 ANAPC4 UBR3 UBE2H UBE2C BRAP UHRF2 HUWE1 UBE2K UBR5 UBE2M DDB2 MDM2 FBXL6 AMFR ZER1 FBXL2 SYVN1 GCLC ANAPC10 ANAPC11 UBE3C GCLM STUB1 ARIH1 ERCC8 UBE2D3 UBE2D2 FBXW2 FBXO3 TRAF7 TRAF6 RNF14 FBXO7 RNF144B FBXO2 CBL UBE2L6 CDC23 MALT1 PARK2 BIRC3 UBE2L3 TRIM23 SMURF2 SMURF1 FPGS PAICS UBE2E1 | |
| SEROTONIN_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SEROTONIN_RECEPTOR_ACTIVITY HTR1B HTR1A HTR7 HTR4 HTR2B HTR1D HTR3B HTR1F HTR5A HTR1E HTR2A | |
| INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC5A5 SLC20A1 SLC20A2 SLC34A1 ANKH SLC34A3 SLC34A2 SLC17A7 SLC26A4 ADAMTS8 SLC17A3 SLC17A4 SLC17A1 SLC17A2 SLC25A3 SLC13A4 SLC4A4 ASNA1 SLC4A3 | |
| HISTONE_METHYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/HISTONE_METHYLTRANSFERASE_ACTIVITY SUZ12 EHMT1 PRMT7 PRMT8 EZH2 WHSC1L1 SUV39H1 EED NSD1 SUV39H2 FBXO11 | |
| PROTEIN_DOMAIN_SPECIFIC_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_DOMAIN_SPECIFIC_BINDING HSP90AB1 TLN1 CADM1 SLC22A12 CD2AP PTEN GPX1 NOD2 ARHGAP5 MAPT MICAL1 LPAR2 INSR PAG1 USH2A ADAM9 ARHGEF4 HSP90AA1 SIT1 NOS1AP CD3E CCDC88C LDB1 USHBP1 LDB2 ARHGAP27 CFTR RAD9A NLRP2 IRS1 PPARGC1B ELMO1 CARD11 XPA CARD14 LAT2 SSTR2 WBP2NL LAX1 GRM7 LCK RIPK2 BPY2 ADAM15 CLCN3 ABI2 AFAP1L2 STUB1 SRC ESPN MLF1 FOXH1 PTK2 SQSTM1 BCL2 PYCARD ERCC1 CARD8 CARD9 TBC1D10A ESRRG EVL PTPN12 DOCK4 HOXB1 YWHAH NUP62 BAX KIF20B JAK2 CRK PDZK1 | |
| CARBOHYDRATE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CARBOHYDRATE_BINDING CHIA LMAN2L FGF10 POSTN FSTL1 REG3A CLEC4E ANG SERPINA5 ZNF146 APOA5 ODZ1 KLRB1 PRG2 COLEC10 LGALS12 CHODL COL25A1 LRPAP1 TNFAIP6 PODXL2 KLRG1 CD34 SIGLEC8 VEGFA SIGLEC7 AAMP VCAN EPYC ACR EMCN HDGF POLA1 PF4 LMAN1 CLEC10A MDK CHIT1 GALK1 FCN3 UPK1A CLEC2B FCN2 IMPG2 FCN1 ACAN KRT1 SFTPD KLRAP1 THBS2 FGFBP1 THBS4 MRC1 LPL TNXB LGALS3 LGALS4 COL13A1 LGALS7 LGALS8 STAB2 LGALS9 RPL29 CD207 GCK LAYN CLEC3A CD209 HBEGF TGFBR3 CLEC7A HABP2 | |
| G_PROTEIN_COUPLED_RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/G_PROTEIN_COUPLED_RECEPTOR_BINDING CXCL11 CXCL12 CXCL10 SAA1 SLC9A3R1 PROK2 GHRH CCR2 GHRL CCL1 CXCL1 RTP2 CCL3 CCL2 CXCL5 RTP1 CXCL3 CXCL2 C5 CXCL9 CCL8 PF4 CXCL6 CX3CL1 CCL5 CCL4 CCL28 CCL27 CCL7 CCL26 CCL24 CALCA CCL25 CCL22 CCL23 CCL20 CCL21 CKLF IL8 CCL19 REEP1 CCL16 CCL15 CCL18 CCL17 CCL11 CCL13 PSMC5 CXCL14 CXCL13 CXCL16 CORT XCL1 XCL2 | |
| GTP_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/GTP_BINDING SEPHS1 HBS1L RRAGA ARF6 RRAGB RRAGC NMUR2 CLP1 RALB RHOB RALA TGM3 SCG5 RAB26 MX1 EIF2B2 GNL1 GNL3 RHOH RAP2B EEF1A1 GTPBP1 GTPBP4 GTPBP6 NCF1 RAN ARHGEF5 TPX2 ARFIP2 GEM DRG2 TRIM23 ARL3 RND3 NME1 ARF3 RAB22A RHEB RIT1 ARL8A ARL8B RIT2 SEPT6 SEPT7 GBP2 GBP1 | |
| HYDRO_LYASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/HYDRO_LYASE_ACTIVITY ALAD ECH1 CA14 CA5A EHHADH CA5B ECHS1 HADHA HADHB AUH ENO2 ENO3 FH ENO1 GMDS ACO1 CA12 CA11 CA9 CA8 CA7 CA6 CA4 CA3 CA2 CA1 CBS | |
| NUCLEOTIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/NUCLEOTIDE_BINDING BTK MAP3K6 MAP3K5 DHX38 LTB4R WNK4 VPS4A TLK1 RAB26 TLK2 EIF2B2 GTPBP1 GTPBP4 GTPBP6 RAN ABCB11 NCF1 PIM1 WNK1 OLA1 WNK3 GEM WNK2 MYH9 SARS2 MARK1 MARK2 RND3 RFC1 NME1 RFC2 ARL8A ARL8B NEK6 STK17B ARF6 MYO9B STK17A PXK TGFBR1 NIM1 SPHK1 ARFIP2 OXSR1 ABCG1 ABCG2 RERG CDC42BPG ARF3 CDC42BPA RHEB TNK1 RIT1 RIT2 CHST15 CDC42BPB ABCF1 BCKDK SEPHS1 ABCF2 ACVRL1 NUAK2 LATS1 LATS2 NUBP1 NUBP2 NMUR2 SLC22A4 SIK3 NT5C RAP2B CDC6 SRPK2 AIFM2 ACTA1 ARHGEF5 TP53 TPX2 CFTR SRPK1 RAD51 MTRR EIF4A3 MAST1 SIK2 MAST2 MKNK2 POLA1 MKNK1 GALK1 DGKE SNRK ABCD2 ABCD4 PDS5B NLK TRIM23 APRT RPS6KA5 RPS6KA4 RAB22A HSPA4L ABCC3 DGKZ PPP2R4 ABCC1 PGK1 ABCC8 ABCC5 PGK2 ABCC6 SIK1 STK38 ZAK STK36 HBS1L TTN DMPK NLRC4 DDX25 CLP1 RALB RALA PRKACB MX1 GNL1 GNL3 MYO6 TWF2 MYO3A STK4 CDKL5 STK3 MAP4K3 NVL MAP4K4 MAP4K5 SMARCA5 SEPT6 SEPT7 GBP2 GBP1 ME1 ABCA7 GCLC STK11 MAP4K2 MAP4K1 RRAGA ABCA2 ABCA4 ABCA3 RRAGB RRAGC IRAK3 DYRK3 DYRK2 STK38L GABARAPL2 EEF1A1 ABCB8 EPB42 PIF1 ABCB1 ABCB7 TINAG ABCB6 TRNT1 ATP7A ABL1 MYH10 PC ATP7B PEX6 PINK1 MOV10L1 PPOX ACVR1B ORC4 PEX1 RHOB RHOH HSP90AA1 PRKCI MINK1 DAPK2 DAPK3 NLRP1 NEK11 DAPK1 ARL3 DHRS3 ERN1 ORC5 ERN2 DMC1 ACVR1 BRSK2 TRIB2 TRIB1 N4BP2 ERCC6 CDK11A CDK11B TOR1A TGM3 SCG5 NOX4 MSH6 MSH2 DRG2 GSG2 SMC4 NDOR1 ICK TSSK1A GCK TSSK2 APAF1 TSSK4 BMPR1B TSSK3 TSSK6 BMPR1A | |
| COPPER_ION_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/COPPER_ION_BINDING ATOX1 TP53 SOD1 DCT APOA4 ATP7A TYR RNF7 ANG CCS LOX PRNP MT3 ATP7B AOC3 | |
| DI___TRI_VALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DI___TRI_VALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY CLDN16 SLC8A1 ITPR3 ITPR1 ITPR2 ATP2B1 SLC11A2 ATP2B3 ATP2B4 ATP2A2 FXN ATP2A3 ATP2C1 ATP2A1 SLC30A4 SLC30A5 CCS SLC30A3 SLC31A2 SLC40A1 SLC31A1 SLC39A2 | |
| TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY NRP2 NRP1 ACVRL1 EFNA3 DDR2 ACVR1C ACVR1B TIE1 INSR EGFR TYRO3 EFNB3 ALK ACVR2A DDR1 ACVR2B IGF2R PDGFRL PDGFRA ROR1 PDGFRB ROR2 MST1R EFNA4 ACVR1 FGFR1 FGFR4 ERBB4 ERBB3 PTK7 EPHB2 IGF1R MUSK EPHB6 TEK CRIM1 CSF1R LTK FLT1 FLT3 RYK FLT4 TGFBR1 MET TGFBR2 TRIM27 AXL KDR EPHA5 NTRK1 MERTK | |
| SYMPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SYMPORTER_ACTIVITY SLC5A3 SLC5A2 SLC20A1 SLC15A1 SLC6A2 SLC20A2 SLC15A2 SLC5A1 SLC4A4 SLC12A7 SLC12A1 SLC12A9 SLC12A2 SLC12A3 SLC12A4 SLC10A2 SLC34A3 SLC10A1 SLC17A7 SLC17A5 SLC6A9 SLC17A3 SLC6A8 SLC17A4 SLC6A5 SLC17A2 SLC6A6 SLC13A2 SLC5A6 SLC13A4 SLC5A7 | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS SAT1 F13A1 CERS5 ALAS2 NAA16 GNPAT KAT7 KAT8 AGPAT2 KAT6B KAT6A TAF1L ELP4 SPTLC1 SPTLC2 GGT5 PNPLA3 ZDHHC17 EP300 DGAT1 LRAT SMARCE1 DGAT2 NCOA3 EDF1 SRCAP CROT HMGCS1 HAT1 ACAT1 HADHA HADHB LPCAT1 TGM1 TGM2 TGM3 AANAT TGM5 ACSL3 GTF3C4 SOAT1 TAF1 SOAT2 CPT1B TAF5 NAT1 CREBBP NAT2 CS MCAT BRCA2 ACLY CPT1A ATE1 OXSM GLYAT NAA15 CERS1 YKT6 | |
| ANTIPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ANTIPORTER_ACTIVITY SLC25A11 SLC9A7 SLC9A6 SLC9A5 SLC9A3 SLC9A2 SLC3A2 SLC4A3 SLC7A11 SLC9A1 | |
| HEMATOPOIETIN_INTERFERON_CLASSD200_DOMAIN_CYTOKINE_RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/HEMATOPOIETIN_INTERFERON_CLASSD200_DOMAIN_CYTOKINE_RECEPTOR_BINDING CSF3 CSF2 IFNA21 CTF1 IFNA2 IFNA7 IFNA5 IFNG IFNA4 ERAP1 IFNK IFNA8 PRL IL4 IL3 IL5 IL7 IL25 IL21 OSM GH1 CNTF SDCBP IFNA14 IFNA13 IL12B IFNA16 IL2 IFNA17 | |
| MONOSACCHARIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/MONOSACCHARIDE_BINDING MRC1 ACR GALK1 CD207 GCK CD209 LMAN2L UPK1A COLEC10 LMAN1 LGALS9 | |
| OXIDOREDUCTASE_ACTIVITY_ACTING_ON_SULFUR_GROUP_OF_DONORS http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_ACTING_ON_SULFUR_GROUP_OF_DONORS GSR SUOX MSRA TXNDC2 DLD TXNRD2 TXNRD1 QSOX1 MSRB2 MSRB3 | |
| DNA_HELICASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DNA_HELICASE_ACTIVITY XRCC5 XRCC6 INO80 SETX IGHMBP2 ERCC8 ERCC6 CHD2 CHD1 SUPV3L1 ERCC3 CHD4 CHD3 ERCC2 RECQL4 DHX9 PIF1 G3BP1 WRN ATRX RECQL SMARCAL1 RAD54B RUVBL2 RUVBL1 | |
| ENDODEOXYRIBONUCLEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ENDODEOXYRIBONUCLEASE_ACTIVITY DNASE2 EXO1 ERCC5 MRE11A MBD4 OGG1 ERCC4 APEX1 FEN1 RAD50 ERCC1 | |
| PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY CDC14B PTPN22 PTPN21 TIMM50 PTEN PTPRJ PTPRK PTPRM PTPRF PTPRG PTPRH PTPRN2 PTPRR PTPRS PTPRT PTPRU PTPRN PTPRO TPTE DUSP12 DUSP11 MTMR3 PTPLA MTMR7 PTPN7 PTPRB PTPRC PTPN6 PTPRD PTPN9 PTPRE PTPN3 PTPN18 PTPRZ1 PTPN2 PTPN5 PTPRA PTPN4 EPM2A PTPN14 PTPN12 PTPN11 CDC25B DUSP5 DUSP3 DUSP2 PTP4A3 DUSP1 PTP4A2 PTPN1 DUSP8 DUSP7 DUSP6 | |
| RAS_GTPASE_ACTIVATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RAS_GTPASE_ACTIVATOR_ACTIVITY PREX1 RAB3GAP1 MYO9B RANGAP1 ARHGAP4 RASAL2 ALDH1A1 RASAL1 CDC42EP2 ARHGAP5 RASGRP3 GMIP SOS1 ARAP1 ARAP3 RAPGEF2 ERRFI1 ARHGEF10L RASA1 RASA2 RALBP1 NF1 ARHGAP27 ARHGAP29 PREX2 THY1 DOCK4 OPHN1 ARHGAP10 | |
| PHOSPHORIC_MONOESTER_HYDROLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHORIC_MONOESTER_HYDROLASE_ACTIVITY PTPN22 PTPN21 NT5C3 NT5C2 BPNT1 NANP PTPRJ PTPRK PTPRM PTPRF PTPRG PTPRN2 PTPRH FBP1 PTPRR PTPRS PTPRT PTPRU FBP2 PTPRN PTPRO TPTE PNKP PPP1CA PPP5C PPP2R3B ACP6 PFKFB1 ACP5 ACP2 DUSP12 DUSP11 OCRL ACP1 PPP1R3D PPP1R3C DUSP13 PTPLA CTDNEP1 INPP5K PTPN7 PTPN6 PTPN9 PTPN18 PTPN3 PTPN2 PTPN5 EPM2A PTPN4 PTPN14 PTPN12 PTPN11 PTPN1 IMPA2 IMPA1 CDC14B SYNJ1 TIMM50 PSPH PTEN DLGAP5 NT5E DLG1 NT5C MINPP1 PPAP2C CYCS CILP APTX PPM1G G6PC MTMR14 PPM1D PPEF2 SBF1 PPEF1 LCK INPP4B PPM1M CTDP1 PPP2R2A INPP1 PPP6C PPM1A PPM1B MTMR2 MTMR3 PSPHP1 PPP2CB INPP5E INPP5D PPAP2A PPAP2B MTMR7 PTPRB PTPRC PTPRD PTPRE PTPRZ1 PTPRA CDKN3 CDC25B DUSP5 DUSP4 DUSP3 DUSP2 DUSP1 PTP4A3 PTP4A2 DUSP8 DUSP7 DUSP6 | |
| DAMAGED_DNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/DAMAGED_DNA_BINDING MSH6 REV1 MSH3 POLH MSH2 DDB1 APTX PMS2P1 XPA MPG XPC DDB2 TDG FANCG OGG1 POLQ ALKBH3 ALKBH2 ERCC4 FEN1 ERCC1 | |
| RNA_HELICASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RNA_HELICASE_ACTIVITY DHX8 DHX9 UPF1 SKIV2L G3BP1 DDX1 DDX6 EIF4A3 DDX56 DDX17 DDX18 DHX38 DDX23 DDX3X DDX25 DHX15 DHX16 DDX21 RAD54B DDX20 DDX10 DDX54 DDX43 DDX39A | |
| LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS http://www.broadinstitute.org/gsea/msigdb/cards/LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS BTD DZIP3 CTPS RNF217 HLCS CAD MYLIP MTHFD1 GSS WWP2 WWP1 FBXO22 ANAPC2 ANAPC5 ANAPC4 UBR3 UBE2H UBE2C GMPS BRAP UHRF2 HUWE1 UBE2K UBR5 UBE2M DDB2 MDM2 AMFR FBXL6 ZER1 FBXL2 ADSS SYVN1 GCLC ANAPC10 CTPS2 ASNS UBE3C ANAPC11 GCLM STUB1 PFAS ERCC8 ARIH1 UBE2D3 UBE2D2 FBXW2 TRAF7 FBXO3 TRAF6 RNF14 FBXO7 RNF144B FBXO2 CBL UBE2L6 CDC23 MALT1 PARK2 BIRC3 CPS1 TRIM23 UBE2L3 SMURF2 SMURF1 FPGS PAICS UBE2E1 | |
| LIPID_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/LIPID_BINDING SYT1 OSBP TSPO PREX1 NDUFAB1 SYP STARD3 APOA4 PIGK ACOT7 MCTP2 PICALM APOA1 APOE PGRMC1 ZFYVE16 SDPR APOF APOA5 PGRMC2 S1PR3 SHC1 CETP S1PR2 LPAR2 LPAR3 ZFYVE1 S1PR4 SHBG ALDH6A1 CCDC88A PLA2G15 PIGU PRKCI ESR2 PCLO GLTP THY1 MCTP1 NPC2 SCIN PLA2G7 PEBP1 DOC2B AKR1D1 PTAFR GC CAV1 HDLBP PAFAH2 GPAA1 ADH5 APOC2 EEA1 ALDH1A1 RASAL1 ANXA9 ALB RASGRP4 RASGRP1 ARAP2 ARAP1 HSD17B4 ARAP3 CD24 WDFY1 CYTH3 EPB41 PSAP MAL CD1D APOL2 PLEKHA3 RAB35 BAX ADAP2 CPNE1 SYTL4 FABP4 CPNE3 GRK5 FABP2 FABP7 SCP2 PLEKHA2 FABP5 PLEKHA1 | |
| KINASE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/KINASE_BINDING BCAR1 PDLIM5 HINT1 FOXO3 PRDX3 UBQLN1 LATS1 NOD2 CDKN2A CDKN2B CEP250 CDKN2C CDKN2D CDK5RAP2 TOP2B FIZ1 TOP2A MAP2K7 INSR KIF13B ADAM9 DLG1 IRAK1 BCL10 SIT1 ADAM10 ZC3HC1 CCDC88A RELA SOCS1 PICK1 PTPRR RAD9A RB1 IRS1 SPDYC SPDYA CCND3 LAX1 LCK AKAP5 AKAP7 MAP3K13 AKAP3 MAP3K12 AKAP4 AKAP12 TRIB3 ITGB2 AKAP11 LLGL1 IGF1R SQSTM1 CD4 CD24 TPRKB APC PTPRC MOB1B CAMK2N1 YWHAG RPS6KA4 AVPR1B AVPR1A MAPK8IP2 MAPK8IP3 FAF1 MAPK8IP1 GRK5 TRIP6 | |
| ALDO_KETO_REDUCTASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ALDO_KETO_REDUCTASE_ACTIVITY AKR1C3 AKR1C4 AKR1A1 AKR1B10 MIOX AKR1B1 AKR7A2 tAKR AKR7A3 SPR AKR1C1 ALDH3A1 | |
| PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR EFNA3 CLK1 PRKX MAP3K7 PRKY MAP3K6 MAP3K5 MAP3K4 CLK3 CLK2 COL4A3BP MAP3K9 WNK4 ILK MAP3K8 PIK3C3 PIK3CA TLK1 TLK2 MAP2K7 MAP2K6 PIK3CG TYRO3 TNIK BCR EFNB3 ROCK1 ROCK2 PIK3CB WNK1 PIM1 WNK3 PIM2 WNK2 MARK4 MARK1 MARK2 PNKP MAPK1 EIF2AK1 MAPK6 MAPK4 PDGFRL PDGFRA ROR1 PDGFRB ROR2 MAPK9 MAPK8 MST1R EFNA4 MAPK7 EIF2AK2 NEK4 EIF2AK3 NEK6 EIF2AK4 CHKA COASY TAB1 CDK5R1 ERBB4 ERBB3 NEK2 PFKFB2 ERBB2 PFKFB1 STK17B STRADB STK17A CHEK2 PXK UHMK1 EPHB2 EPHB6 VRK1 MUSK VRK2 TAOK2 MAP2K1 MAP2K3 TGFBR1 NIM1 TGFBR2 TAOK3 SPHK1 TRIO DUSP21 OXSR1 ATM KDR EPHA5 CDC42BPG STRADA NTRK1 CDC42BPA TNK2 CDC42BPB NRP2 BCKDK ACVRL1 NRP1 NUAK2 ARSG LATS1 LATS2 CAMKK2 PDPK1 TGFA SIK3 TAF1L SRPK2 LYN PIK3C2A CDK1 PHKG2 PI4KA PI4KB SRPK1 GTF2H1 MAST1 SIK2 RIPK1 MAP3K10 BRDT TXK MAP3K13 MAP3K12 MAP3K11 PIKFYVE HK2 MKNK2 MKNK1 HK1 KIT DGKA GALK2 GALK1 DGKE SNRK PTK2B DGKD DGKG PDK1 CSNK1A1 PDK2 BRD2 DGKQ NLK PDK3 PDK4 AXL TRIM27 CSNK2B DGKK NADK MAPK11 DGKI MAPK10 RPS6KA5 KHK TP53RK RPS6KA3 CSNK1D MAPK12 RPS6KA1 RPS6KA2 MAPK13 EPGN CSNK1E GSK3B MAPK14 MAPK15 DGKZ CIT SIK1 STK38 ZAK STK36 TTK RPS6KB2 ITPKB TTN PRKCB ITPKA DMPK CSNK2A2 PRKACG CSNK2A1 PRKACB INSR EGFR TWF1 PDXK CSNK1G2 RPS6KC1 STK4 STK3 MAP4K3 MAP4K4 MAP4K5 CDKL1 PI4K2A TESK1 RIPK3 RIPK2 TESK2 MVK RIPK4 KALRN PHKA2 STK16 FGFR1 FGFR4 CCL2 GNE STK11 MAPKAPK5 STK10 PHKA1 MAPKAPK3 PTK7 MAP4K2 MAP4K1 MAPKAPK2 CCL4 IRAK3 PTK6 TEK LMTK2 DYRK2 STK19 STK38L CSF1R NR4A3 ITK TAF1 RYK MET SMG1 GLYCTK IKBKE PLK4 PLK3 ULK1 PLK1 DYRK1A CPNE3 MERTK MYLK PIP4K2B PRKAG3 PRKAG1 PINK1 SKAP1 DDR2 ACVR1C AKT1 ACVR1B PAK2 CDK10 TIE1 PAK1 CHUK AKT2 IRAK2 IRAK1 SGK1 SGK2 PFKL LIMK2 SGK3 LIMK1 PRKCI PFKP PRKCH MINK1 CDK9 PRKCG PFKM PBK CDK7 ALK PRKCE DAPK2 DAPK3 CDK5 CDK2 NEK11 XRCC6BP1 GAK CDK3 TYK2 PRKD1 ACVR2A DDR1 HUNK ACVR2B CRKL IGF2R PKM2 HIPK3 PKLR ERN1 ERN2 PRKD3 ACVR1 XYLB PRKCZ FRK BRSK2 BRSK1 TRIB2 TRIB1 EXOSC10 N4BP2 IGF1R MAP3K3 MAP3K2 ETNK1 PIK3R3 CRIM1 PIK3R2 LTK FLT1 FLT3 FLT4 GCK TSSK1A TSSK2 TSSK4 IPPK TSSK3 TSSK6 | |
| OXIDOREDUCTASE_ACTIVITY_GO_0016705 http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_GO_0016705 CYP2J2 CYP11B1 CYP11B2 TH PTGS1 EGLN2 KMO PAH EGLN1 BBOX1 MSMO1 NOS2 HMOX2 NOS2P1 TYR CYP39A1 P4HA2 P4HA1 PLOD2 HMOX1 PLOD3 NOS3 ASPH KDM4A CYP19A1 P4HB NOS1 FADS1 SCD CYP26A1 CYP7B1 CYP4A11 CYP4F8 CYP17A1 DOHH CYP2A6 CYP8B1 SC5DL | |
| LIPASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/LIPASE_ACTIVITY F2RL2 PNLIP CASR PDIA3 EDNRA AOAH PLA2G1B MGLL PLA1A PLCB2 PLD3 PLD2 PLD1 CCKBR PLA2G15 LGALS13 LYPLA1 PNPLA3 AADAC PNPLA8 PLCE1 CHRM5 CHRM3 CCR5 PRDX6 CHRM1 PLA2G2A PLA2G6 PLA2G3 PLA2G2E PLA2G2D PLA2G5 C3AR1 ENPP7 APOC2 BDKRB2 PLCH1 PLCD1 LPL PNLIPRP1 PNLIPRP2 PLA2G10 LIPG SMPD1 PLA2G4C SMPD4 PLA2G4B LIPE SMPD2 LIPF | |
| STEROID_DEHYDROGENASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/STEROID_DEHYDROGENASE_ACTIVITY HSD17B11 HSD3B2 HSD17B10 HSD3B1 HSD17B14 DHRS9 HSD17B4 HSD3BP4 AKR1C1 HSD17B7 NSDHL | |
| SUGAR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SUGAR_BINDING ACR LMAN2L POLA1 LMAN1 CLEC10A REG3A GALK1 CLEC4E FCN3 CLEC2B FCN2 UPK1A FCN1 KRT1 SFTPD KLRAP1 KLRB1 MRC1 LGALS3 LGALS4 PRG2 COLEC10 LGALS7 LGALS12 LGALS8 LGALS9 KLRG1 GCK CD207 SIGLEC8 CD209 CLEC3A SIGLEC7 CLEC7A | |
| INWARD_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/INWARD_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY KCNJ5 KCNJ15 KCNQ5 KCNJ4 KCNJ6 KCNK6 KCNJ10 KCNK1 KCNJ12 KCNJ3 KCNJ14 KCNJ1 | |
| RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY ALS2 ARHGEF3 SERGEF ARHGEF2 ARHGEF1 MADD PREX1 PREX2 RCC1 FARP1 ARHGEF11 FARP2 RCBTB2 DOCK2 TIAM1 RASGRP4 SOS1 RAPGEF5 RAPGEF2 | |
| CATION_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CATION_BINDING S100A4 GDA S100A8 S100A7 LTBP4 S100A9 TPD52 DNASE1L2 DNASE1L3 DSPP ERAP2 S100A1 CDH24 CDHR5 CIZ1 YY1 PIM1 PCLO LETM1 PITPNM3 PRDM4 PIAS2 CDK5R1 FDX1 DUSP12 CALR CALU MYT2 ARIH2 RPS27 RPS29 CDA GPD2 KLF7 CRIP1 HPCAL1 CRIP2 HPCAL4 CSRP1 S100A13 S100A12 CBLC CBLB RNF7 RNF4 RNF5 TRPS1 NOTCH4 ATP2A1 ZEB1 GLI2 KCNIP2 CANX KCNIP3 CAMKK2 LNPEP MMP20 TYR ZNF146 TCHH ACO2 TP53 MMP17 MMP16 MMP15 MMP14 MMP13 GPR98 MMP12 LRPAP1 MMP10 CHMP1A NCS1 BNIP2 SIAH1 CAPS REPS2 POLR2K POLR2I CETN1 EEA1 PKD2 PPP3CB LIMD1 PEX12 THBS3 THBS4 PLEK MEX3B CAPN9 BIRC5 SOD1 ZNF22 MSRB2 MSRB3 RLF MNAT1 LRP1 FBLN2 RASSF1 CALM3 APOBEC1 ATOX1 MMP9 MMP8 ADH1B RCVRN APOBEC3G APOBEC3F MMP2 CALB1 MMP1 APOA4 ZNF185 TIMM9 TPT1 RGN LOX ASPH CIB1 FECH CA12 SCUBE1 HDAC10 STIM1 TIMM8B ISCU THBD SLU7 MYNN ME1 MYL2 PEF1 ECE2 RNF11 ADAM30 DYRK2 TESC S100P RABIF CPNE6 DMP1 BRCA1 SLC25A12 ATP7A SLC25A13 S100B FLG S100G PHEX ABL1 PDCD6 ABL2 ATP7B SEPX1 DUOX2 MAN1B1 CTCF MCTP2 ANG GSN ITIH1 KPNB1 MT3 MAN1A1 PDP1 MCTP1 NUCB2 SCIN MDM2 ZFPM2 CA2 PPM1M MDM4 PRNP AOC3 FKBP9 CABP2 SPOCK2 CABP5 ADAMTS13 CABP1 TIMM10 CABP4 TIMM13 DCT CALML3 RASGRP1 PRSS2 COMP FCN2 FCN1 PRSS3 TGM3 CCS CD4 CALML5 CHD4 HRC FBN1 ANXA1 SIRT6 SPARC MAN1C1 SIRT2 HSP90B1 ANXA10 MEP1B LTA4H GCA RCN1 CSN2 RCN2 | |
| PHOSPHORUS_OXYGEN_LYASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHORUS_OXYGEN_LYASE_ACTIVITY GUCY2F ADCY9 ADCY7 ADCY8 GUCY1A2 GUCY1A3 GUCY1B3 ADCY10 GUCY2C GUCY2D | |
| SPECIFIC_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SPECIFIC_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY GLIS3 ZBTB32 ETV7 GLIS1 DEK ZNF202 PDX1 SOX9 ZNF345 FOS MEIS2 GFI1B ZNF148 VEZF1 NR2F2 NR2F1 BRD8 ZBTB7B ZNF281 ERF RXRB NFRKB RXRA FOXN1 ZNF141 ZNF143 NR0B1 USF1 PROX1 NOTCH2 ATF4 PKNOX1 NRL IRF7 ZNF136 | |
| PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC20A1 SLC20A2 SLC34A1 ANKH SLC34A3 SLC34A2 SLC17A7 ADAMTS8 SLC17A3 SLC17A4 SLC17A1 SLC17A2 SLC25A3 | |
| SULFOTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SULFOTRANSFERASE_ACTIVITY GAL3ST2 TPST1 TPST2 HS3ST6 HS3ST5 SULT2B1 CHST10 CHST12 CHST11 CHST14 CHST13 SULT1C2 HS6ST1 SULT1E1 SULT1A4 GAL3ST1 UST CHST2 CHST3 CHST4 CHST5 CHST1 CHST7 CHST6 CHST9 CHST8 CHST15 HS3ST3B1 | |
| PHOSPHOTRANSFERASE_ACTIVITY_PHOSPHATE_GROUP_AS_ACCEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOTRANSFERASE_ACTIVITY_PHOSPHATE_GROUP_AS_ACCEPTOR MPP1 MPP2 MPP3 AK1 DTYMK CASK AK2 AK5 PMVK NME6 NME4 NME5 NME2 NME1 TJP2 GUK1 DLG2 DLG1 | |
| SERINE_TYPE_PEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SERINE_TYPE_PEPTIDASE_ACTIVITY ACR PREP CORIN CELA3A MASP1 MASP2 PRSS1 C1R C1S PCSK2 HTRA2 TPP1 HTRA1 PRSS2 TPP2 KLKB1 PRSS3 TOR1A PCSK9 LTF CFI CFD PRSS36 PCSK6 HGFAC DPP4 F11 F12 KLK8 F10 KLK2 CELA2B GZMA F9 GZMB F7 KLK1 FURIN TMPRSS6 PLG PROC APEH F2 CPD CTSG | |
| CATION_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CATION_CHANNEL_ACTIVITY KCNC1 KCNC4 KCNC3 CUL5 KCNK7 KCNK6 KCNK5 MS4A2 CHRNA4 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 KCND3 SCN2B SCN2A RYR3 RYR1 RYR2 KCNMB3 ORAI1 KCNMB4 SCN1B KCNA2 KCNA1 CACNB1 KCNA4 CACNB2 KCNA3 KCNA6 CACNB3 CACNB4 KCNA5 KCNJ3 KCNMB1 KCNJ1 KCNMB2 KCNS3 KCNS1 GAR1 SCN9A TRPC1 CACNA2D1 TRPC4 TRPC3 TRPC5 KCNB2 KCNK1 CACNA1S KCNK3 KCNK4 KCNJ5 P2RX4 KCNJ4 P2RX7 KCNJ6 SLC4A11 P2RX1 P2RX3 CACNA1G CHRNB4 CHRNB3 CACNA1H CHRND CHRNB2 CACNA1E CACNA1F CACNA1C CACNA1D CHRNE CACNA1A CACNA1B KCNK17 KCNH1 KCNJ15 TRPV1 KCNJ10 KCNIP2 KCNJ12 KCNJ14 KCNK10 KCNQ5 KCNQ3 CCT8L2 TRPV5 SCN7A TRPV6 KCNQ2 KCNQ1 KCNG2 CACNG5 CACNG4 CACNG2 CACNG1 TRPM2 TRPM1 KCNA10 SCN11A KCNH2 KCNH3 KCNH4 SHROOM2 KCNE1 PKD2 KCNE2 SCNN1G SCNN1B HTR3A HTR3B SCN5A SCNN1D NOX5 ACCN1 KCNN4 KCNN3 KCNN2 SCN4B SCN4A | |
| SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC5A3 SLC5A2 SLC9A7 SLC9A6 SLC15A1 SLC20A1 SLC9A5 SLC20A2 SLC6A2 SLC15A2 SLC5A1 SLC9A3 SLC9A2 SLC22A11 SLC22A4 SLC4A4 SLC4A3 SLC12A7 SLC12A1 SLC12A9 SLC12A2 SLC12A3 SLC12A4 SLC22A7 SLC3A2 SLC10A2 ANKH SLC34A3 SLC7A11 SLC10A1 SLC17A7 SLC25A11 SLC17A5 SLC6A9 SLC16A7 SLC17A3 SLC17A4 SLC6A8 SLC6A5 SLCO1B1 SLC6A6 SLC17A2 SLC13A2 SLC5A6 SLC13A4 SLC5A7 SLC9A1 | |
| RAS_GTPASE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/RAS_GTPASE_BINDING ALS2 RAB3GAP1 RTKN RANBP9 CDC42EP2 DMXL2 IPO5 RAPGEF6 RANBP3 RANBP1 RANBP2 GOLGA5 CDC42EP5 PARD6A RILP ARHGEF2 RALBP1 ARFIP2 IPO9 IPO8 DOCK4 PLCE1 IPO7 SGSM3 CYFIP1 | |
| DRUG_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/DRUG_BINDING ACR SIGMAR1 FKBP6 FKBP5 FKBP4 FKBP3 NKTR PPIE PPIH PPIG ALB PPID PPIC TOP2A FKBP2 NFATC1 | |
| ATP_DEPENDENT_HELICASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ATP_DEPENDENT_HELICASE_ACTIVITY XRCC5 SKIV2L SNRNP200 XRCC6 DDX18 DDX3X DHX38 DDX23 DDX25 CHD2 CHD1 DDX21 DDX20 DDX43 CHD4 CHD3 DHX8 DHX9 UPF1 PIF1 G3BP1 RECQL EIF4A3 DDX56 RUVBL2 DDX54 DDX39A | |
| ARYLSULFATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ARYLSULFATASE_ACTIVITY ARSB ARSD ARSE ARSF SULF2 ARSG ARSH SULF1 ARSI ARSJ ARSA ARSK | |
| ZINC_ION_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ZINC_ION_BINDING SEPX1 GDA APOBEC1 MMP9 MMP8 ADH1B CTCF APOBEC3G ZEB1 GLI2 MMP2 APOBEC3F MMP1 LNPEP MMP20 ZNF185 ZNF146 TIMM9 ERAP2 KPNB1 MT3 CIZ1 CA12 YY1 TP53 HDAC10 MMP17 MMP16 MMP15 MMP14 MMP13 TIMM8B MMP12 MMP10 CHMP1A PRDM4 MDM2 SLU7 ZFPM2 SIAH1 PIAS2 CA2 MDM4 MYNN ADAMTS13 POLR2K POLR2I TIMM10 EEA1 DUSP12 TIMM13 MYT2 ECE2 RPS27 ARIH2 RPS29 CDA RNF11 LIMD1 CD4 ADAM30 PEX12 CHD4 KLF7 CRIP1 RABIF CRIP2 SIRT6 BIRC5 CSRP1 SOD1 ZNF22 MSRB2 BRCA1 SIRT2 MSRB3 S100A12 RLF CBLC MNAT1 CBLB RNF7 RNF4 S100B RNF5 TRPS1 RASSF1 MEP1B LTA4H PHEX | |
| PROTEIN_HOMODIMERIZATION_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_HOMODIMERIZATION_ACTIVITY ALS2 SLC9A7 S100A6 CADM3 NRBP1 CADM1 VAPB TPD52 GDNF AGXT TGFB2 APOA4 APOA2 MAP3K5 NLRC4 PLOD1 APOE MAP3K9 CHRNA7 S100A1 ACTN4 KIAA1804 CST3 ACTN3 MYH9 STK4 EIF2AK1 IGSF1 CLIP1 ABAT ATPIF1 CAV2 SNX6 RRAGA DSCAML1 APOC2 MYO9B ADRB3 PVRL1 PVRL3 UPK1A NPM1 PVRL2 IL17F CDA GYS2 AIMP1 TCF3 CARD8 MLL CARD9 CUBN S100A11 SMAD4 TREX1 SMAD3 CIDEA TPD52L1 FOXP3 ABCG4 ABCG1 ABCG2 FOXP2 S100B TSC2 MAFA HEXB NR6A1 HPS4 BNIP3 SDCBP2 CDSN TYR PRMT8 GOLGA5 TOP2A CCDC88A ADAM10 HSP90AA1 GZMA LDB1 AMBP INHBB XPA ADRB2 MAP3K10 MAP3K13 MAP3K12 AOC3 MAP3K11 CLN6 TYRP1 NFS1 EEA1 ZBTB16 HPRT1 ERCC5 MOAP1 ANXA9 CEP57 SH3GLB1 DGKD BCL2 PYCARD CD4 MSH6 CR2 MSH3 MSH2 CENPF TBX1 BIRC5 VWF SP1 GLA BAX BNIP3L TRPC4AP PPP2R4 HPGD BARD1 | |
| HEPARIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/HEPARIN_BINDING LPL TNXB COL13A1 HDGF FGF10 POSTN COL25A1 PF4 FSTL1 MDK LRPAP1 RPL29 ANG SERPINA5 ZNF146 VEGFA APOA5 AAMP HBEGF ODZ1 FGFBP1 THBS2 THBS4 | |
| RNA_POLYMERASE_II_TRANSCRIPTION_MEDIATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RNA_POLYMERASE_II_TRANSCRIPTION_MEDIATOR_ACTIVITY MED12 MED24 CNOT2 MED14 MED13 PPARGC1A PPARGC1B MED4 MED30 MED17 MED26 THRAP3 MED1 | |
| LIGASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/LIGASE_ACTIVITY XRCC4 DZIP3 BTD CTPS RNF217 MYLIP ACSS2 WWP2 WWP1 FBXO22 ANAPC2 YARS DARS ANAPC5 ANAPC4 UBR3 LIG4 SARS2 BRAP UHRF2 HUWE1 UBR5 RNF139 AMFR FBXL6 PCCB PCCA FBXL2 ADSS GCLC SYVN1 FARS2 CTPS2 ANAPC10 ANAPC11 GCLM KARS ARIH1 UBE2D3 UBE2D2 FBXW2 TRAF7 FBXO3 TRAF6 RNF14 FBXO7 RTCD1 FBXO2 ACACA GARS CDC23 UBE2L6 MALT1 UBE2L3 CPS1 SMURF2 SMURF1 FPGS PC UBE2E1 NARS CAD QARS HLCS GSS MTHFD1 SUCLA2 SARS UBE2H UBE2C GMPS UBE2K UBE2M DDB2 FARSB MDM2 SLC27A6 FARSA SLC27A2 ZER1 SLC27A5 ASNS UBE3C VARS STUB1 PFAS ERCC8 ACSL1 MARS2 ACSL4 MARS RNF144B CBL PARK2 BIRC3 TRIM23 PAICS | |
| CALCIUM_ION_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CALCIUM_ION_BINDING S100A4 S100A8 S100A7 LTBP4 S100A9 RCVRN DNASE1L2 TPD52 DNASE1L3 CALB1 DSPP TPT1 RGN ASPH S100A1 CDH24 CIB1 CDHR5 SCUBE1 STIM1 PCLO LETM1 PITPNM3 THBD CDK5R1 MYL2 CALR CALU PEF1 GPD2 TESC S100P HPCAL1 CPNE6 HPCAL4 DMP1 S100A13 S100A12 SLC25A12 SLC25A13 FLG ATP2A1 NOTCH4 S100G PDCD6 DUOX2 MAN1B1 KCNIP2 CANX KCNIP3 CAMKK2 MCTP2 GSN ITIH1 TCHH MAN1A1 PDP1 GPR98 MCTP1 LRPAP1 NCS1 BNIP2 SCIN NUCB2 CAPS FKBP9 REPS2 CABP2 SPOCK2 CABP5 ADAMTS13 CABP1 CABP4 CETN1 CALML3 FCN2 COMP RASGRP1 PRSS2 FCN1 PRSS3 PKD2 PPP3CB TGM3 CALML5 THBS3 HRC THBS4 PLEK MEX3B FBN1 CAPN9 ANXA1 SPARC MAN1C1 HSP90B1 LRP1 ANXA10 FBLN2 CALM3 GCA RCN1 RCN2 CSN2 | |
| HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_NOT_PEPTIDEBONDS http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_NOT_PEPTIDEBONDS ACR APOBEC2 GDA APOBEC1 NIT1 DPYS APOBEC3G HDAC7 APOBEC3F ADA GCH1 GLS2 ADAT1 MTHFD1 MTHFD2 ARG1 ASPA ATIC CRMP1 ARG2 PGLYRP2 ASRGL1 CDA DCTD AGA ACY1 ADARB2 DARS PDF UPB1 PADI3 HDAC10 DPYSL3 HDAC11 PADI4 DPYSL2 AMPD3 SIRT2 AMPD1 HDAC5 HDAC3 HDAC2 HDAC1 FAAH HDAC8 HDAC6 | |
| CATION_TRANSPORTING_ATPASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CATION_TRANSPORTING_ATPASE_ACTIVITY ATP6V0C ATP6V1C1 ATP2B1 ATP2B3 ATP6V0E1 ATP2B4 ATP2A2 ATP2A3 ATP2C1 ATP2A1 ATP6V1B2 | |
| PROTEIN_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_TRANSPORTER_ACTIVITY EIF4ENIF1 XPO6 MCL1 TSNAX IPO9 ABCG1 COG3 SEC61B CCT6B ZFYVE16 COX18 RAMP1 COG1 COG2 | |
| OXIDOREDUCTASE_ACTIVITY_GO_0016616 http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_GO_0016616 LDHC LDHB LDHA EHHADH ADH1B HSD3BP4 AKR1C3 RDH8 IDH3G AKR1C4 MIOX AKR7A2 AKR7A3 SPR HADH IMPDH1 IMPDH2 AKR1C1 DHRS9 CBR3 GRHPR RDH5 DHRS2 H6PD AKR1B10 HSD3B2 ME1 HSD17B10 ME3 ME2 HSD3B1 HSD17B14 UGDH ADH6 ADH7 HADHA HADHB ALDH3A1 CBR1 AKR1A1 ADH4 IDH1 BDH2 HSD17B4 TSTA3 BDH1 HSD17B7 NSDHL GPD1 tAKR IDH3B RDH12 RDH11 RDH10 AKR1B1 PHGDH RDH16 HPGD | |
| GTPASE_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GTPASE_REGULATOR_ACTIVITY ALS2 DLC1 RAB3GAP2 RAB3GAP1 IQGAP2 RANGAP1 IQGAP1 RCBTB2 GBF1 TIAM2 TIAM1 RAPGEF6 RAPGEF5 RAPGEF4 RAPGEF3 RAPGEF2 EIF2B2 EIF2B3 EIF2B4 EIF2B5 NET1 BCR MADD PREX2 FARP1 FARP2 THY1 PLCE1 OPHN1 KALRN FGD2 ARHGDIG FGD1 ARFGAP3 PTPLAD1 SIPA1 RUNDC3A CDC42SE1 MYO9B RCC1 ARFGEF1 RIMS1 RASAL2 RASAL1 CDC42EP2 DOCK2 DOCK1 GMIP ARAP1 ARAP3 FGD5 FGD6 ARHGDIA ARHGEF10L ARHGDIB FGD4 ABR VAV3 TRIO DOCK4 RGS1 RGS2 RGS3 RGS4 TSC2 RGS5 RGS6 TNK2 RGS9 ARHGAP10 PREX1 ARL2BP ARHGAP4 ARHGAP5 IPO5 RANBP1 ERRFI1 ARL2 ARHGEF3 ARHGEF2 ARHGEF1 RALBP1 ARHGAP27 ARHGEF17 ARHGAP29 HERC1 WAS ARHGEF11 ANKRD27 BNIP2 IPO7 KRIT1 WASL RAPGEFL1 RABGAP1 RAP1GAP RTKN ALDH1A1 RGS11 RGS12 RASGRP3 RASGRP4 SOS1 RASA3 RASA4 RASA1 RASA2 GPS1 CYTH1 SERGEF GDI2 CYTH2 CYTH3 NF1 RGS16 RACGAP1 EIF2B1 RALGDS RGS14 GPS2 DIS3 RGS20 ADAP1 CHN2 CYTH4 | |
| METALLOPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/METALLOPEPTIDASE_ACTIVITY SPG7 METAP1 METAP2 THOP1 MMP9 MMP8 IDE ANPEP RCE1 MMP28 ENPEP MMP3 MMP2 MMP24 LNPEP MMP20 PAPPA FAP CPA2 CPA3 ERAP1 ERAP2 CPA1 DPEP1 PEPD MMP17 MMP16 MMP15 MMP14 MMP13 MMP12 MMP11 CHMP1A PGCP PMPCA ADAMTS2 ECEL1 KEL MME ECE2 ACE PITRM1 ZMPSTE24 MBTPS2 METAP1D MMP23B MEP1A C9orf3 PAPPA2 CPB2 | |
| SOLUTE_SODIUM_SYMPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SOLUTE_SODIUM_SYMPORTER_ACTIVITY SLC5A3 SLC5A2 SLC6A2 SLC5A1 SLC10A2 SLC10A1 SLC6A9 SLC6A8 SLC6A5 SLC6A6 SLC13A2 SLC5A6 SLC5A7 | |
| RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY HMGN1 MEF2C MYOD1 MED24 CNOT2 TBP PDX1 MED21 TCEAL1 MED20 CBFB HOXD10 BATF PROP1 MED26 GATA4 CIITA RXRB RELA RXRA NKX2-8 GABPA FOXN1 MED12 MED14 MED13 CSDA NR0B1 PROX1 PPARGC1A PPARGC1B JUNB ELL2 HOXD9 UHRF1 HIF1A PRDM4 HNF4A ABT1 TIAL1 JUN MED17 MNX1 SMARCA5 TFAP4 LITAF ONECUT2 MYEF2 SOX9 SRF SOX8 VPS72 ATF2 HOXA1 TCERG1 MEIS2 LHX1 HTATSF1 JUND SNF8 LHX3 TEAD4 TEF NKX3-2 BTF3 TAF9 VEZF1 RUNX2 KLF5 TAF2 SREBF1 TAF4 UTF1 TCF7 MLL TAF6 EPAS1 KLF13 TAF7 GTF2A1L TEAD3 USF1 USF2 SREBF2 ATF6 NOTCH2 ATF5 ATF4 GTF2F1 GTF2F2 RFX1 RFX3 TCF12 ZFHX3 TCF15 E2F2 TAF1C ZBTB32 TAF1A SOX21 HTATIP2 FOXK2 DEK CTCF ZNF202 ZNF345 TMF1 FOS GFI1B GTF2A1 ZNF148 CREG1 SOX15 SPIB SOX18 NR2F2 BRD8 NR2F1 ZNF281 RAX ZNF354A TBX10 GMEB2 CNTRL SOX12 SF1 ZNF141 ZNF143 GTF2B PURA GTF2H1 MED6 HOXC10 TAF11 TAF10 MED4 TAF13 HOXC11 TAF12 HOXC13 GTF2I NRL ZNF136 ASH1L ZFPM2 CUX1 TBX19 MED1 SUPT3H GLIS3 ETV7 GLIS1 NFYC NFIX HCFC2 TCF7L2 NFAT5 MLLT1 TCEA1 MAF ZBTB7B ERF TBX3 TBX5 NFRKB SOX30 MYF5 ISL1 PKNOX1 MED30 ILF2 SP2 DBP IRF7 SP4 IRF8 THRAP3 IRF2 NEUROD1 IRF3 IRF4 NR5A2 | |
| SODIUM_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SODIUM_CHANNEL_ACTIVITY SHROOM2 SCN1B SCN2B SCN2A CACNA1S ACCN1 SLC4A11 PKD2 SCN9A SCN4B SCN11A SCNN1G SCN7A SCNN1B SCN5A SCN4A SCNN1D | |
| RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM http://www.broadinstitute.org/gsea/msigdb/cards/RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM SRSF10 BCAS2 PRPF3 SF3B4 SF3B3 SF3A3 SMNDC1 SNRNP40 SRSF4 DDX23 PRPF8 KHSRP SRRM1 SLU7 TRA2B SCAF11 LSM1 GEMIN2 TXNL4A | |
| METABOTROPIC_GLUTAMATEGABA_B_LIKE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/METABOTROPIC_GLUTAMATEGABA_B_LIKE_RECEPTOR_ACTIVITY GRM5 GRM4 GRM3 GRM2 GRM8 GRM7 GRM6 GABBR1 GABBR2 GRM1 | |
| AMINE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/AMINE_RECEPTOR_ACTIVITY DRD1 DRD3 DRD2 DRD5 DRD4 ADRB3 HRH1 HTR1B HTR1A HRH3 HRH2 ADRA2A ADRA2C ADRA2B HTR1D HTR3B HTR5A HTR1F HTR1E HTR4 ADRB2 CHRM5 ADRB1 CHRM4 CHRM3 CHRM2 CHRM1 HTR7 HTR6 ADRA1B ADRA1A HTR2B ADRA1D HTR2A | |
| STEROL_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/STEROL_BINDING STARD3 SYP OSBP CAV1 TSPO APOA1 NPC2 APOF CETP HSD17B4 SCP2 | |
| VITAMIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/VITAMIN_BINDING GC HACL1 FOLR3 FOLR2 FOLR1 ALB TTPA ABAT AGXT PCCA OPN4 PC | |
| PURINE_NUCLEOTIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PURINE_NUCLEOTIDE_BINDING BTK MAP3K6 MAP3K5 DHX38 WNK4 VPS4A TLK1 RAB26 TLK2 EIF2B2 GTPBP1 GTPBP4 GTPBP6 ABCB11 NCF1 RAN WNK1 PIM1 OLA1 WNK3 WNK2 GEM MYH9 SARS2 MARK1 MARK2 RND3 RFC1 RFC2 NME1 ARL8A ARL8B NEK6 STK17B ARF6 MYO9B PXK STK17A TGFBR1 NIM1 SPHK1 ARFIP2 OXSR1 ABCG1 ABCG2 RERG CDC42BPG ARF3 CDC42BPA RHEB TNK1 RIT1 RIT2 CHST15 CDC42BPB ABCF1 BCKDK SEPHS1 ABCF2 ACVRL1 NUAK2 LATS1 LATS2 NMUR2 SIK3 RAP2B SRPK2 ACTA1 AIFM2 ARHGEF5 TP53 TPX2 CFTR SRPK1 RAD51 MTRR EIF4A3 MAST1 SIK2 MAST2 MKNK2 MKNK1 GALK1 SNRK DGKE ABCD2 ABCD4 PDS5B NLK TRIM23 APRT RPS6KA5 RPS6KA4 RAB22A ABCC3 HSPA4L DGKZ PPP2R4 ABCC1 PGK1 ABCC8 ABCC5 PGK2 ABCC6 SIK1 ZAK STK38 STK36 HBS1L TTN DMPK NLRC4 DDX25 CLP1 RALB RALA PRKACB MX1 GNL1 GNL3 TWF2 MYO6 MYO3A STK4 CDKL5 STK3 MAP4K3 NVL MAP4K4 MAP4K5 SMARCA5 SEPT6 SEPT7 GBP2 GBP1 ME1 ABCA7 GCLC STK11 MAP4K2 RRAGA MAP4K1 ABCA2 ABCA4 ABCA3 RRAGB RRAGC IRAK3 DYRK3 DYRK2 STK38L GABARAPL2 EEF1A1 ABCB8 EPB42 PIF1 ABCB1 ABCB7 ABCB6 ATP7A TRNT1 ABL1 PC ATP7B MYH10 PEX6 PINK1 PPOX MOV10L1 ACVR1B PEX1 RHOB RHOH HSP90AA1 PRKCI MINK1 DAPK2 DAPK3 NEK11 NLRP1 ARL3 DAPK1 ERN1 ERN2 DMC1 ACVR1 BRSK2 TRIB1 N4BP2 ERCC6 CDK11A CDK11B TOR1A TGM3 SCG5 NOX4 MSH6 MSH2 DRG2 GSG2 SMC4 NDOR1 ICK TSSK1A GCK TSSK2 BMPR1B TSSK4 TSSK3 TSSK6 BMPR1A | |
| SH2_DOMAIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SH2_DOMAIN_BINDING SIT1 AFAP1L2 IRS1 SRC LAT2 PTK2 ARHGAP5 NUP62 SQSTM1 LAX1 LCK JAK2 INSR CRK PAG1 | |
| VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY KCNH1 KCNC1 KCNJ15 KCNC4 KCNC3 KCNA2 KCNA1 KCNA4 KCNA3 KCNA6 KCNJ10 KCNA5 KCNJ12 KCNIP2 KCNJ3 KCNJ14 KCNJ1 KCNS3 KCNQ5 KCNS1 KCNQ3 KCNK6 KCNE1 KCNE2 KCNQ2 KCNQ1 KCNG2 KCND3 KCNB2 KCNK1 KCNJ5 KCNJ4 KCNJ6 KCNH2 KCNH3 KCNH4 | |
| SMALL_CONJUGATING_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SMALL_CONJUGATING_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY SENP2 USP29 USP53 UFD1L USP5 UCHL1 USP21 USP12 UCHL3 VCPIP1 | |
| HYDROLASE_ACTIVITY_ACTING_ON_GLYCOSYL_BONDS http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_ACTING_ON_GLYCOSYL_BONDS NAGLU CHIA HEXB MAN1B1 SMUG1 CHIT1 GLB1 MUTYH NAGPA HPSE2 HPSE NAGA PARG TREH AMY2B MAN2B1 NTHL1 CCNO AMY2A APEX1 IDUA HYAL1 MSH6 SPACA3 HYAL2 MAN1A2 MSH3 KL GUSB LYZ MAN1A1 HYAL4 FUCA1 MAN1C1 MANBA ADPRH GBA3 MAN2A1 GBA2 GLA MGEA5 TDG NEU1 OGG1 AMY1B LCT NEU4 | |
| ANION_CATION_SYMPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ANION_CATION_SYMPORTER_ACTIVITY SLC12A7 SLC12A9 SLC12A1 SLC20A1 SLC12A2 SLC12A3 SLC20A2 SLC12A4 SLC34A3 SLC17A7 SLC17A3 SLC17A4 SLC17A2 SLC13A2 SLC13A4 SLC4A4 | |
| RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY ACVRL1 ZAK MAP4K1 ACVR1C MAP3K7 MAP3K6 ACVR1B MAP3K5 MAP3K4 MAP3K3 MAP3K9 IRAK2 IRAK1 TGFBR1 NLK TGFBR2 MAPK11 MAPK10 MAPK1 ACVR2A IKBKE ACVR2B MAPK12 MAPK13 MAPK14 MAPK4 MAPK15 MAP3K10 MAPK9 MAPK8 MAPK7 MAP3K13 ACVR1 MAP3K11 | |
| HYDROLASE_ACTIVITY_HYDROLYZING_O_GLYCOSYL_COMPOUNDS http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_HYDROLYZING_O_GLYCOSYL_COMPOUNDS NAGLU CHIA HEXB MAN1B1 CHIT1 GLB1 NAGPA HPSE2 HPSE NAGA PARG TREH AMY2B MAN2B1 AMY2A IDUA HYAL1 HYAL2 SPACA3 MAN1A2 KL GUSB LYZ MAN1A1 HYAL4 MAN1C1 FUCA1 MANBA GBA3 MAN2A1 GBA2 GLA MGEA5 NEU1 AMY1B LCT NEU4 | |
| SINGLE_STRANDED_DNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SINGLE_STRANDED_DNA_BINDING RAD23B HMGB2 RAD23A MLH1 WBP11 TERF2IP RPA4 POT1 YBX1 RPA3 MYT2 RPA1 IGHMBP2 FUBP1 RPA2 ERCC5 PCBP1 PMS2 ERCC4 TERF2 ERCC1 RBMS1 RAD51AP1 MSH3 MSH2 SUB1 HNRNPA2B1 TP53 TREX1 HNRNPA1 PURB PURA RAD51 HNRPDL XPC | |
| INTERLEUKIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/INTERLEUKIN_BINDING A2M IL1R1 IL9R HAX1 IL6ST IL7R IL12RB2 IL12RB1 IL10RB IL4R IL10RA CSF2RB IL15RA IL2RG EBI3 IL13RA2 IL2RB IL2RA IL6R CXCR2 IL18BP IL12A IL5RA IL3RA IL22RA2 | |
| ENZYME_ACTIVATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ENZYME_ACTIVATOR_ACTIVITY DLC1 ALS2 RAB3GAP2 DBF4 RAB3GAP1 SAE1 RCVRN FGF13 RANGAP1 APOA4 APOA2 MAP3K5 APOA1 CASP8AP2 APOA5 GUCA2B RAPGEF2 FRS2 DNAJC1 DBNL BCL10 F10 BCR MADD PREX2 THY1 ADRM1 RFC1 HSPB2 OPHN1 CDK5R1 ARFGAP3 FZR1 PTPLAD1 SIPA1 APOC2 CTSA AFAP1L2 MYO9B ARFGEF1 PLAA RASAL2 RASAL1 CDC42EP2 DOCK1 GMIP DNMT3L PRKRA ARAP1 ARAP3 ARHGEF10L CARD8 ABR VAV3 MOB1B MALT1 TPD52L1 DOCK4 RGS1 RGS2 RGS3 RGS4 UBA2 TSC2 RGS5 RGS6 RGS9 AHSA1 DNAJB6 ARHGAP10 PREX1 MMP24 ARHGAP4 CTAGE5 ARHGAP5 NOD1 CASP9 CASP1 ERRFI1 ARL1 AIFM3 RALBP1 MMP17 ARHGAP27 MMP16 MMP15 ARHGAP29 PRKCD BNIP2 GHRL CXCL1 RABGAP1 RAP1GAP PPP1R12B ALDH1A1 RGS11 RGS12 RASGRP3 SOS1 ALOX5AP PITRM1 CD24 RASA3 RASA4 GTF3C4 RASA1 RASA2 GUCA1B GUCA1A GUCA1C PSAP NF1 RGS16 RACGAP1 TRIM23 RGS14 GMFB RGS20 GMFG ADAP1 MAPK8IP2 CHN2 PPP2R4 IGFBP3 IL2 | |
| ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS_PHOSPHORYLATIVE_MECHANISM http://www.broadinstitute.org/gsea/msigdb/cards/ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS_PHOSPHORYLATIVE_MECHANISM FXYD2 ATP1B1 ATP4A ATP1B3 ATP4B ATP1B2 ABCB11 ATP1A3 ATP1A4 ATP1A1 ATP1A2 ATP2B1 ATP7A ATP2B3 ATP2B4 ATP2A2 ATP2A3 ATP2C1 ATP2A1 ATP7B | |
| EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY GLRB GLRA1 GLRA2 STX1B P2RX4 P2RX7 P2RX1 P2RX3 CHRNB4 CHRNA4 CHRNB3 CHRND CHRNA7 CHRNB2 CHRNA6 HTR3A CHRNA1 HTR3B CHRNE CHRNA3 CHRNA2 | |
| LYASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/LYASE_ACTIVITY HCCS ALAD ADCY7 ADCY8 EHHADH LTC4S AUH SCLY HDC GUCY1A2 GUCY1A3 ADCY10 DDC FECH ACO1 CA12 CA11 UMPS CA9 CA8 SDS CA7 CA6 CA4 ADSL GUCY1B3 CA3 CA2 CA1 UROD GGCX ALDOA HACL1 ECH1 MVD CA14 ALDOC CA5A CA5B ALDOB ECHS1 ASL HADHA HADHB ACCS ENO2 ENO3 GLO1 PTS AMD1 NTHL1 GAD1 APEX1 FH ENO1 BCKDHA GUCY2F ODC1 GMDS BCKDHB ACMSD GUCY2C GUCY2D PCK1 ADCY9 MLYCD OGG1 CRYM CBS | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS ITGA2B TUSC3 B3GALT5 B3GALT4 ALG2 ALG3 ALG5 ALG6 ALG8 POMGNT1 B3GALNT1 RPN1 PIGB OGT PIGA PIGZ CSGALNACT1 PIGV UGCG FUT10 ODF3B MGAT2 MAGT1 MTAP GALNT8 EXT1 GALNT3 GALNT2 GCNT4 GALNT1 GCNT3 GCNT2 FUT9 FUT8 GALNT7 FUT7 GALNT6 FUT6 GALNT5 GALNT4 FUT5 EXTL2 STT3B B3GNT8 UGGT1 STT3A B3GNT5 UGGT2 B3GNT6 B4GALNT2 GYS2 FUT4 FUT1 A4GNT UGT8 FUT2 B4GALT6 GCNT1 B4GALT7 B4GALT4 C1GALT1 SDF2 B4GALNT1 B4GALT5 MGAT4B B4GALT1 MGAT4A B4GALT3 A4GALT B4GALT2 B3GALT2 GYG2 B3GAT2 GBE1 PYGM LARGE PYGL DPM1 DPM2 DPM3 POFUT1 | |
| MANNOSYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MANNOSYLTRANSFERASE_ACTIVITY PIGZ ALG2 ALG3 PIGV DPM1 PIGB DPM2 DPM3 ALG8 SDF2 | |
| SH3_DOMAIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SH3_DOMAIN_BINDING CD3E ARHGAP27 ABI2 RAD9A EVL AFAP1L2 CD2AP PTPN12 ESPN ELMO1 GPX1 MAPT MICAL1 ADAM15 ADAM9 | |
| OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH_GROUP_OF_DONORS http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH_GROUP_OF_DONORS PYCR1 MTHFD2 MTHFR AIFM2 ADH4 ETFDH QDPR ALDH4A1 SARDH PRODH | |
| CARBOXY_LYASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBOXY_LYASE_ACTIVITY GGCX BCKDHA DDC ODC1 MVD BCKDHB ACMSD PCK1 UMPS MLYCD HDC AMD1 UROD GAD1 | |
| INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHODIESTERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHODIESTERASE_ACTIVITY F2RL2 C3AR1 CASR CCKBR BDKRB2 EDNRA CHRM5 PLCE1 CCR5 CHRM3 CHRM1 PLCD1 PLCB2 | |
| MICROTUBULE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/MICROTUBULE_BINDING HOOK3 NDE1 TUBGCP6 TUBGCP5 RAE1 TARDBP KATNA1 MAPT CEP290 CLASP1 CLASP2 CDK5RAP2 DCX APC DYNC1I1 ARHGEF2 CCDC88A KIF5B HTT BIRC5 POLB MARK4 SUN2 UXT ATG4D ATG4C MAP1S ATG4A TPPP CLIP1 MAPRE1 PRNP LRPPRC | |
| MICROTUBULE_MOTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MICROTUBULE_MOTOR_ACTIVITY KIF23 DYNC1I1 BBS4 KIF22 KIF3B KIF4A KIF11 KIF5B KIF5C CENPE DNAI2 KIFC3 KIF2C DNALI1 KIF1B APPBP2 | |
| LIPOPROTEIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/LIPOPROTEIN_BINDING ANKRA2 LDLR SORL1 COLEC12 STAB2 TLR6 SCARF1 LRPAP1 APOA4 APOL2 APOBR CDH13 LRP1 STAB1 CXCL16 MAPT LRP6 VLDLR | |
| OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PEROXIDE_AS_ACCEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PEROXIDE_AS_ACCEPTOR MGST3 GPX2 EPX IPCEF1 GPX4 GPX3 PRDX4 GSTZ1 MPO PRDX2 CYGB CAT | |
| PHOSPHATASE_INHIBITOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHATASE_INHIBITOR_ACTIVITY TESC PPP1R2 PPME1 SET PPP1R8 PPP1R1B PPP1R1A ANP32E LMTK2 PTN SAG | |
| NON_MEMBRANE_SPANNING_PROTEIN_TYROSINE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NON_MEMBRANE_SPANNING_PROTEIN_TYROSINE_KINASE_ACTIVITY TYK2 FRK ITK PTK2B ERBB2 PTK6 DYRK1A TXK CLK1 TNK2 NR4A3 | |
| THIOLESTER_HYDROLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/THIOLESTER_HYDROLASE_ACTIVITY USP5 UCHL1 PPT1 OTUB2 USP29 ACOT9 HAGH USP53 ACOT8 ACOT11 ACOT12 USP21 USP12 UCHL3 HIBCH YOD1 | |
| ORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLCO1B3 SLCO1A2 SLC22A7 SLCO1B1 SLC22A8 ABCC3 SLC22A6 SLC22A11 ABCC2 ABCC5 | |
| NEUROPEPTIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/NEUROPEPTIDE_BINDING MCHR1 CCKAR CCKBR TACR3 TACR2 TACR1 BRS3 NPY6R HCRTR2 SSTR4 SSTR5 KISS1R SSTR2 SSTR3 GALR1 SSTR1 NMUR1 NMUR2 GALR3 MRGPRX2 MC2R GALR2 NMBR | |
| TASTE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TASTE_RECEPTOR_ACTIVITY TAS2R1 TAS2R4 TAS2R5 TAS2R3 TAS1R3 TAS1R1 TAS1R2 TAS2R16 TAS2R13 TAS2R14 TAS2R9 TAS2R8 TAS2R43 TAS2R7 TAS2R10 | |
| UDP_GLYCOSYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/UDP_GLYCOSYLTRANSFERASE_ACTIVITY GALNT3 GCNT4 GALNT2 GALNT1 GCNT3 GCNT2 GALNT7 B3GALT5 GALNT6 B3GALT4 GALNT5 GALNT4 EXTL2 B3GNT8 UGGT1 POMGNT1 UGT1A8 B3GNT5 UGGT2 XYLT1 B3GALNT1 B4GALNT2 GYS2 OGT A4GNT UGT8 GCNT1 B4GALT7 PIGA B4GALNT1 MGAT4B B4GALT1 MGAT4A B3GALT2 CSGALNACT1 UGCG GYG2 B3GAT2 MGAT2 LARGE EXT1 GALNT8 | |
| PHOSPHOLIPID_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOLIPID_BINDING SYT1 PAFAH2 PREX1 GPAA1 EEA1 APOA4 RASAL1 PIGK APOA1 PICALM ANXA9 MCTP2 APOE SDPR ZFYVE16 APOA5 ARAP2 CETP ARAP1 SHC1 CD24 ARAP3 ZFYVE1 WDFY1 CCDC88A CYTH3 EPB41 PLA2G15 PIGU PRKCI PCLO THY1 MCTP1 PLEKHA3 RAB35 SCIN ADAP2 PLA2G7 CPNE1 SYTL4 PEBP1 CPNE3 GRK5 DOC2B PTAFR PLEKHA2 PLEKHA1 | |
| CARBONATE_DEHYDRATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBONATE_DEHYDRATASE_ACTIVITY CA14 CA5A CA12 CA11 CA5B CA9 CA8 CA7 CA6 CA4 CA3 CA2 CA1 | |
| ELECTRON_CARRIER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ELECTRON_CARRIER_ACTIVITY CYB5R3 CYB5R4 COX11 CYB5R2 CYC1 ADH1B COX5A IDO1 GLDC GPX2 NDUFS7 GSR HMOX2 AKR1C4 NDUFS4 FXN P4HA2 NDUFS8 AKR7A2 AKR7A3 SRD5A1 ASPH NQO1 LOXL2 NDUFS3 NDUFS2 SARDH NDUFS1 NQO2 NCF2 AIFM1 NCF1 CYCS QDPR NDUFA13 CYP1A2 DHDH POR MTRR UQCR11 DHRS3 TXNDC2 DLD TXNRD2 TXNRD1 AOC2 DEGS1 ME1 ME2 FDX1 UGDH ADH5 ADH6 KMO ALDH1A2 AKR1A1 ETFDH HAAO ALDH4A1 DMGDH HSD17B6 TSTA3 ETFB CYP19A1 ETFA NOX4 NDUFA9 MAOB FDXR IDH3B PHYH CYB561 CYBA SDHD AKR1B1 ALDH2 PHGDH RDH16 | |
| AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC38A3 SLC7A8 SLC7A9 SLC7A4 SLC7A5 SLC7A6 SLC1A4 SLC1A5 SLC1A2 SLC1A3 SERINC1 SLC1A6 SLC25A22 SLC1A7 SLC43A1 SLC1A1 OCA2 PDPN SLC6A14 SLC7A10 SLC3A1 SLC7A11 SLC25A12 SLC6A9 SLC25A13 SLC7A2 SLC6A5 CTNS SLC25A15 | |
| HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS MSH6 MUTYH MSH3 TDG OGG1 APEX1 SMUG1 CCNO NTHL1 ADPRH | |
| SMALL_CONJUGATING_PROTEIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SMALL_CONJUGATING_PROTEIN_BINDING UBE2N CIITA BCL10 DZIP3 TOM1L1 NUP62 TSG101 SQSTM1 UCHL1 PML TOP2A SIRT2 | |
| LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY PPARD THRA THRB NR3C2 NR3C1 NR2E1 NR2C1 PGR VDR NR1D1 PGRMC2 NR2F6 RARA RARB BRD8 AR RARG PTGER3 RXRB RXRA RXRG ESR2 NR4A3 AHR NR1I3 | |
| VOLTAGE_GATED_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/VOLTAGE_GATED_CHANNEL_ACTIVITY KCNH1 KCNJ15 KCNC1 KCNC4 KCNK15 KCNC3 KCNJ10 HVCN1 KCNIP2 KCNJ12 KCNJ14 KCNQ5 KCNQ3 KCNK6 SCN7A KCNQ2 KCNQ1 KCNG2 KCND3 SCN2B SCN2A CACNG5 CACNG4 CACNG2 CACNG1 SCN11A KCNH2 KCNH3 KCNH4 CLCN1 CLCN3 CLCN2 SCN1B KCNA2 KCNA1 CLCNKA KCNA4 CACNB1 KCNA3 CACNB2 CLCNKB CACNB3 KCNA6 CACNB4 KCNA5 KCNJ3 KCNJ1 KCNS3 KCNS1 SCN9A KCNE1 PKD2 KCNE2 SCN5A CACNA2D1 KCNB2 NOX1 KCNK1 CACNA1S KCNJ5 KCNJ4 KCNJ6 CACNA1G CACNA1H SCN4B CACNA1E CACNA1F CACNA1C CACNA1D SCN4A CACNA1A CLCN4 CACNA1B | |
| HYDROLASE_ACTIVITY_ACTING_ON_ESTER_BONDS http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_ACTING_ON_ESTER_BONDS RPP38 PTPN22 RNASEH1 PTPN21 DNASE1L2 DNASE1L3 DNASE1L1 ISG20 USP53 NT5C3 NT5C2 PLA2G1B RPP30 PLA1A PTPRJ PLD3 PTPRK PLD2 PLD1 PTPRM PTPRF PTPRG PTPRH PTPRR PTPRS RAD9A PTPRT PTPRU PTPRN PTPRO AADAC RAD1 PNKP PPP1CA CCR5 NME1 PLA2G2A PLA2G2E PLA2G2D ENPP7 PPP2R3B ENPP2 ENPP3 ACP6 MRE11A PFKFB1 ACP5 ACP2 PPT1 DUSP12 BDKRB2 DUSP11 OCRL ACP1 PPP1R3D PPP1R3C DUSP13 GALNS CTDNEP1 NTHL1 PTPN18 EPM2A TREX2 PTPN14 TREX1 PTPN12 PTPN11 POP1 PON2 POP4 PLA2G4C PLA2G4B POP7 RPP40 ARSB ARSD ARSE PDIA3 ARSF ARSG ARSH SYNJ1 ARSI ARSJ ARSK PTEN EDNRA USP12 NT5E NT5C MINPP1 STS CCKBR EXOSC7 PGAP1 EXOSC2 TP53 APTX LGALS13 PDE10A MBD4 RAD50 USP29 G6PC MTMR14 PPEF2 PPEF1 USP21 PLA2G6 PLA2G3 CTDP1 PLA2G5 PPP6C USP5 MTMR2 MTMR3 PSPHP1 PDE1B PDE1C PDE1A REXO2 PPP2CB MTMR7 FEN1 CES1P1 GDE1 CES2 PNLIPRP1 PNLIPRP2 CES1 PLA2G10 PTPRZ1 PDE3A CDKN3 DUSP5 DUSP4 DUSP3 DUSP2 PDE2A DUSP1 PTP4A3 PPP1R8 PTP4A2 ARSA OGG1 DUSP8 DUSP7 DUSP6 F2RL2 CASR PDE3B CNP OTUB2 IDS RNASE7 PDE4A PDE4B RNASE8 BPNT1 NANP DFFA PTPRN2 DFFB PLA2G15 FBP1 LYPLA1 PDE4D FBP2 PDE4C RNASEH2A PNPLA3 TPTE GNS PNPLA8 PLCE1 XRN2 PPP5C C3AR1 ACHE PPME1 APOC2 PLCH1 PTPLA INPP5K PTPN7 PTPN6 LPL PTPN9 PTPN3 PTPN2 PTPN5 PTPN4 WRN DNASE2 PDE7B PDE7A PTPN1 PNLIP IMPA2 IMPA1 CDC14B DICER1 UCHL1 TIMM50 PSPH ACOT9 ACOT8 DLGAP5 ANG AOAH ACOT11 ACOT12 MGLL DBR1 YOD1 PLCB2 DLG1 PPAP2C CYCS CILP HAGH PPM1G PPM1D CHRM5 CHRM3 SBF1 PRDX6 CHRM1 LCK ERN2 UCHL3 INPP4B PPM1M PPP2R2A INPP1 PPM1A PPM1B N4BP2 ERCC5 PLCD1 INPP5E INPP5D PPAP2A PPAP2B ERCC4 APEX1 ERCC1 PTPRB EXO1 PTPRC RNASE1 PTPRD PTPRE RNASE2 RNASE3 PTPRA RNASE6 CDC25B SULF2 MAP1S SULF1 SMPD1 LIPG HIBCH SMPD4 LIPE SMPD2 ERI1 LIPF | |
| BETA_TUBULIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/BETA_TUBULIN_BINDING GABARAPL2 UXT GABARAPL1 MAP1S VAPB ARL8A ARL8B RACGAP1 GABARAP LRPPRC | |
| FUCOSYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/FUCOSYLTRANSFERASE_ACTIVITY FUT9 FUT8 FUT7 FUT6 FUT5 FUT10 FUT4 FUT1 FUT2 POFUT1 | |
| GATED_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GATED_CHANNEL_ACTIVITY KCNC1 KCNC4 KCNC3 CNGB1 KCNK6 CHRNA4 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 KCND3 SCN2B SCN2A CNGA3 RYR3 RYR1 RYR2 KCNMB3 CLCN1 ORAI1 KCNMB4 CLCN3 CLCN2 SCN1B KCNA2 KCNA1 KCNA4 CACNB1 KCNA3 CACNB2 CACNB3 KCNA6 KCNA5 CACNB4 KCNJ3 KCNMB1 KCNMB2 KCNJ1 KCNS3 KCNS1 ZACN SCN9A TRPC1 TRPC4 CACNA2D1 TRPC3 TRPC5 KCNB2 KCNK1 CACNA1S KCNJ5 KCNJ4 P2RX4 P2RX7 KCNJ6 P2RX1 P2RX3 P2RX2 CACNA1G CHRNB4 CHRNB3 CACNA1H CHRND CACNA1E CHRNB2 CACNA1F CACNA1C CHRNE CACNA1D CLCN4 CACNA1A CACNA1B KCNH1 KCNJ15 KCNK15 GLRA1 GLRA2 KCNJ10 HVCN1 KCNJ12 KCNIP2 KCNJ14 KCNQ5 KCNQ3 CCT8L2 NMUR2 SCN7A KCNQ2 KCNQ1 KCNG2 CACNG5 CACNG4 CFTR CACNG2 CACNG1 STX1B KCNA10 SCN11A KCNH2 KCNH3 KCNH4 SHROOM2 CLCNKA CLCNKB PKD2 KCNE1 KCNE2 SCNN1G HTR3A SCNN1B HTR3B SCN5A SCNN1D GLRB NOX1 KCNN4 ACCN1 KCNN3 KCNN2 SCN4B SCN4A | |
| SUGAR_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SUGAR_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC2A8 SLC5A2 SLC17A5 SLC2A5 PPBP SLC2A4 SLC2A3 SLC5A1 SLC2A2 SLC2A1 SLC37A4 | |
| PROTEASE_INHIBITOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEASE_INHIBITOR_ACTIVITY SERPINA10 TIMP2 SPINK5 SERPINH1 TIMP1 APP LPA SERPINA7 SPINT2 SERPINA6 AGT SERPINA5 SERPINA4 SERPINB10 SERPINA2 SERPINB12 THBS1 SPP2 RECK CST3 CST2 SPINT1 CST1 SERPING1 SERPINI1 SERPINI2 AMBP LCN1 SERPINB9 CST8 RENBP CST6 SERPINF1 SERPINB6 CST7 SERPINB8 CST5 SERPINB7 PI3 SERPINB3 PROS1 | |
| PROTEIN_METHYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_METHYLTRANSFERASE_ACTIVITY LCMT1 EHMT1 EZH2 SUV39H1 SUV39H2 SUZ12 PRMT7 PRMT8 WHSC1L1 EED PCMT1 CARM1 NSD1 FBXO11 | |
| N_ACETYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/N_ACETYLTRANSFERASE_ACTIVITY ELP4 SAT1 TAF1 TAF5 NAT1 NAT2 CREBBP HAT1 BRCA2 EP300 NCOA3 SMARCE1 AANAT EDF1 KAT7 SRCAP KAT8 GTF3C4 KAT6B TAF1L KAT6A | |
| NEUROPEPTIDE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NEUROPEPTIDE_RECEPTOR_ACTIVITY CCKAR MCHR1 TACR3 CCKBR TACR2 TACR1 BRS3 NPY6R SSTR4 HCRTR2 SSTR5 KISS1R SSTR2 SSTR3 GALR1 NMUR1 SSTR1 GALR3 NMUR2 GALR2 MC2R NMBR | |
| RIBONUCLEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RIBONUCLEASE_ACTIVITY RPP38 DICER1 RNASEH1 ISG20 ANG RNASE7 RNASE8 RPP30 DBR1 APEX1 FEN1 EXO1 RNASE1 RNASE2 RNASE3 EXOSC7 RNASE6 EXOSC2 RNASEH2A PPP1R8 POP1 POP4 RPP40 POP7 XRN2 | |
| TRANSCRIPTION_ELONGATION_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSCRIPTION_ELONGATION_REGULATOR_ACTIVITY HMGN1 IKBKAP ELP3 ERCC6 TCEB3B ELL TSFM HTATSF1 SUPT16H SUPT4H1 SUPT5H ELL3 | |
| POLYSACCHARIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/POLYSACCHARIDE_BINDING CHIA HDGF FGF10 POSTN PF4 FSTL1 MDK CHIT1 ANG SERPINA5 IMPG2 ZNF146 APOA5 ACAN ODZ1 FGFBP1 THBS2 THBS4 LPL TNXB COL13A1 CHODL COL25A1 STAB2 LRPAP1 RPL29 TNFAIP6 PODXL2 LAYN VEGFA AAMP HBEGF TGFBR3 VCAN EPYC HABP2 | |
| CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ATP2B1 ATP2B3 SLC8A1 ATP2B4 ATP2A2 ATP2A3 ATP2C1 ATP2A1 ITPR3 ITPR1 ITPR2 | |
| HORMONE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/HORMONE_BINDING CALCR AMHR2 SHBG ADIPOR2 ADIPOR1 NPR1 NRD1 ALDH1A1 ADRB3 ADRB2 MC2R INSR PIK3R1 | |
| VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY CACNA2D1 CACNB1 CACNG5 CACNG4 CACNB2 CACNB3 CACNG2 CACNB4 CACNG1 CACNA1S CACNA1G CACNA1H CACNA1E CACNA1F CACNA1C CACNA1D CACNA1A CACNA1B | |
| IDENTICAL_PROTEIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/IDENTICAL_PROTEIN_BINDING ALS2 S100A6 CADM3 SLC9A7 CADM1 VAPB TPD52 AMOTL1 MRI1 NONO ACTG1 BAK1 APP MAP3K5 PLOD1 APOE MAP3K9 CHRNA7 RAB25 FAS S100A1 FTL SH3GL3 DBNL ROCK1 PCBD1 KIAA1804 MYH9 BRAP EIF2AK1 MED18 ABAT ATPIF1 EIF2AK3 SH3GL2 ITGA2B HACL1 OSTF1 PFKFB3 ERBB2 PFKFB1 NFKBIA MYO9B BCL2L1 ACP1 CD74 ADRB3 RILPL2 PVRL1 PVRL3 UPK1A IL17F PVRL2 GYS2 CDA TCF3 DVL2 MLL SMAD4 S100A11 CIDEA SMAD3 TREX1 TPD52L1 OXSR1 ABCG4 USF2 ABCG1 TAX1BP1 ABCG2 FNBP1 CDC42BPG CDC42BPA POP1 SMURF2 POP4 PARP1 CDC42BPB SCHIP1 GYPA TP63 BNIP3 DAXX CDSN STAC3 RABAC1 BNIPL TYR TRPV4 GOLGA5 TOP2A ALS2CL EXOSC8 ADAM10 GZMA WAS RAD51 INHBB AMBP INHBA DOK2 MAP3K10 RUVBL2 GNAS NHEJ1 MAP3K13 MAP3K12 MAP3K11 CLN6 CLDN16 CLDN17 CLDN18 PLDN CLDN19 ABCD1 NFS1 EEA1 CLDN10 ZBTB16 CLDN11 CLDN12 HPRT1 CLDN14 SUFU CLDN15 RPP14 DOM3Z DGKD BCL2 PCMT1 TRIP10 TRIP13 UPF2 PDS5B PDS5A CSNK2B CLDN22 ELAVL1 BIRC5 TBX1 CLDN20 CLDN23 GLA PTP4A3 FYN RASSF1 BNIP3L PPP2R4 PAICS HPGD BARD1 NRBP1 ZAK PASK ZXDC UBQLN4 TTN AGXT GDNF ZXDA DMPK TGFB2 APOA4 DPY30 NLRC4 APOA2 ROBO1 ROBO2 EGFR STK25 ACTN4 DFFA SNRPN SCUBE1 RELA C14orf166 CST3 FBP1 ACTN2 FADD ACTN3 STK4 IGSF1 HSPB8 PSMA4 CLIP1 MVK TRIM39 SMARCA4 DDX39A CAV2 FGFR3 SNX6 RRAGA APOC2 DSCAML1 ITGB3 KCNRG PSMA7 ITGB1 IRAK3 BLOC1S2 BLOC1S3 GSTK1 ITGB7 NPM1 AIMP1 TRAF7 HNRNPC ARHGDIA CARD8 CARD9 CUBN ITGA2 DCTPP1 CASC3 ITGA4 FOXP3 TRADD FOXP2 HDAC1 S100B TSC2 KCTD17 MAFA IKBKB TRIP6 CLDN8 CLDN7 CLDN9 CLDN4 CLDN3 CLDN6 E2F7 HPS4 NR6A1 HEXB CLDN5 SDCBP2 AKT1 PRMT2 PAK2 PRMT8 CASP8 MKL2 POLG2 ZNF408 CHUK PHC2 IRAK2 SOX10 NOL3 CCDC88A HSP90AA1 LDB1 DAPK2 CDK2 NEK11 MCM6 XPA ADRB2 CLDN1 ORC5 CLDN2 PSME3 COMMD1 PRNP AOC3 TYRP1 SAV1 HCFC1 KITLG DTNBP1 EXOSC10 IGF1R RGMB MOAP1 ERCC5 ANXA9 CEP57 SH3GLB1 PYCARD GPSM2 POU3F2 CD4 PTS NEFL TERF1 MSH6 CR2 MSH3 MSH2 CENPF CBY1 IRF9 ATXN1 MPG CASP10 VWF SP1 BAX TRPC4AP APIP SCAND1 | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS TUSC3 B3GALT5 B3GALT4 ST3GAL1 ST3GAL3 ST3GAL2 ST3GAL5 ST3GAL4 B3GALNT1 ST3GAL6 RPN1 OGT CSGALNACT1 UGCG FUT10 ODF3B MGAT2 EXT1 GCNT4 GCNT3 GCNT2 ST8SIA2 PNP EXTL2 PPAT B3GNT8 UGGT1 B3GNT5 UGGT2 B3GNT6 GYS2 TNKS B4GALT6 B4GALT7 GCNT1 B4GALT4 SDF2 B4GALT5 B4GALT1 MGAT4B MGAT4A ST6GAL1 B4GALT3 B4GALT2 ST6GAL2 B3GAT2 GBE1 QPRT PARP1 ITGA2B ALG2 ALG3 ALG5 ALG6 ALG8 ART1 ST6GALNAC6 ART3 POMGNT1 XYLT1 PIGB PIGA PIGZ PIGV UMPS MAGT1 MTAP GALNT8 GALNT3 GALNT2 GALNT1 FUT9 GALNT7 FUT8 FUT7 GALNT6 GALNT5 FUT6 FUT5 GALNT4 UPP1 UPP2 QTRT1 HPRT1 STT3B TYMP STT3A UGT1A8 B4GALNT2 FUT4 FUT1 FUT2 A4GNT UGT8 C1GALT1 B4GALNT1 A4GALT B3GALT2 SIRT4 SIRT5 GYG2 SIRT6 SIRT1 SIRT3 APRT PYGM LARGE PYGL DPM1 DPM2 DPM3 POFUT1 | |
| NEUTRAL_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NEUTRAL_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC1A4 SLC1A5 SLC38A3 SLC6A9 SERINC1 SLC6A5 SLC7A8 SLC7A10 SLC7A9 SLC7A5 SLC43A1 SLC7A11 | |
| ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC5A5 SLC20A1 GLRA1 SLC20A2 GLRA2 SLC22A11 CCT8L2 NMUR2 SLC25A3 SLC4A2 SLC22A6 SLC4A1 SLC4A4 SLC4A3 SLC12A7 CLCA2 CLCA1 SLC12A9 CLCA4 SLC22A7 SLC22A8 SLC34A1 CFTR SLC34A3 SLC34A2 SLC26A4 BSND ADAMTS8 CLCN1 FXYD1 FXYD3 CLCN3 CLCN2 CLCNKA CLCNKB BEST1 SLCO1A2 PKD2 GLRB SLC12A1 SLC12A2 SLC12A3 SLC12A4 ANKH SLC17A7 SLC25A11 SLCO1B3 SLC17A3 SLC17A4 SLC17A1 SLCO1B1 SLC17A2 ABCC3 SLC13A2 ABCC2 SLC13A4 ASNA1 CLCN4 ABCC5 | |
| SUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ATP1B1 SLC9A7 SLC9A6 ATP1B3 SLC9A5 AQP9 ATP1B2 SLC9A3 SLC9A2 AQP7 SLC35A1 SLC35A2 SLC35A3 ATP2B1 ATP2B3 CUL5 ATP2B4 KCNK7 KCNK6 KCNK5 CHRNA4 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 SLC12A7 CLCA2 SLC12A9 CLCA1 SCN2B CLCA4 PDPN ABCB11 SCN2A NNT ADAMTS8 RHCG PPBP ATP2C1 RYR3 RYR1 RYR2 SURF1 KCNMB3 CLCN1 ORAI1 KCNMB4 CLCN3 CLCN2 SCN1B CACNB1 CACNB2 CACNB3 CACNB4 KCNJ3 KCNMB1 KCNMB2 KCNJ1 SLC11A2 SLC29A1 ATP6V0C SLC29A2 SERINC1 SLC28A2 SLC31A2 SLC31A1 TRPC1 TRPC4 TRPC3 TRPC5 KCNK1 KCNK3 KCNK4 KCNJ5 KCNJ4 KCNJ6 ATP2A2 ATP2A3 LASP1 ATP2A1 CHRNB4 CHRNB3 CHRNB2 CHRND CHRNE CLCN4 SLC9A1 KCNH1 KCNK17 KCNJ15 ATP6V0E1 KCNK15 COX11 SLC20A1 GLRA1 SLC15A1 COX10 SLC15A2 TRPV1 SLC20A2 TRPV2 GLRA2 GJA1 KCNJ10 HVCN1 KCNJ12 KCNIP2 KCNJ14 KCNK10 SLC23A1 FXN SLC23A2 NMUR2 SLC22A4 SLC25A3 TRPV5 SLC22A3 SLC25A1 SLC22A6 TRPV6 SLC22A2 COX15 KCNG2 SLC22A1 ATP4A SLC25A4 SLC25A5 ATP4B SLC22A7 SLC22A8 SLC3A2 CACNG5 CACNG4 CYB5A CFTR CACNG2 SLC3A1 CACNG1 STX1B SLC26A4 KCNA10 ATP6V1C1 BSND SCN11A KCNH2 KCNH3 KCNH4 CLDN16 SHROOM2 COX7A2L SLC19A2 BEST1 PKD2 KCNE1 KCNE2 HTR3A HTR3B SLC8A1 COX7A1 ATP1A3 ATP1A4 ATP1A1 ATP1A2 ITPR3 ITPR1 TRAPPC10 ITPR2 ACCN1 SLC16A2 ACCN4 SLC16A4 SLC16A7 SLC16A6 SLC16A8 ABCC3 ABCC2 CTNS ABCC8 ABCC5 KCNC1 KCNC4 KCNC3 SLC22A13 SLC22A12 SLC6A2 SLC22A14 SLC7A8 SLC7A9 SLC22A11 CNGB1 COX5A SLC7A4 COX5B SLC7A5 SLC7A6 SLC2A8 SLC16A1 SLC2A5 SLC2A4 SLC2A3 SLC2A2 SLC25A22 SLC2A1 MS4A2 SLC4A2 SLC4A1 SLC4A4 SLC4A3 KCND3 SLC34A1 CNGA3 SLC34A3 SLC34A2 SEC61B SLC40A1 FXYD1 FXYD2 FXYD3 SLC38A3 MCL1 KCNA2 KCNA1 COX7B KCNA4 KCNA3 KCNA6 ATP6V1B2 KCNA5 KCNS3 KCNS1 GAR1 ZACN SLC30A4 SCN9A SLC30A5 SLC30A3 CACNA2D1 KCNB2 COX8A SLC6A14 CACNA1S ANKH SLC25A12 P2RX5 ATP7A SLC25A11 P2RX4 P2RX7 SLC25A13 SLC4A11 P2RX1 SLC7A2 SLC25A10 P2RX3 P2RX2 CACNA1G SLC13A2 CACNA1H SLC25A19 CACNA1E SLC13A4 CACNA1F ASNA1 CACNA1C SLC25A15 CACNA1D CACNA1A ATP7B CACNA1B SLC5A3 SLC5A2 SLC5A5 UQCRC1 SLC5A1 SLC1A4 KCNQ5 SLC1A5 SLC1A2 AKR1C4 SLC1A3 KCNQ3 CCT8L2 SLC1A6 SLC1A7 SCN7A KCNQ2 SLC43A1 KCNQ1 SLC1A1 OCA2 TRPM5 COX4I2 COX4I1 SLC7A10 SLC7A11 TRPM2 TRPM1 UQCRH SLC37A4 CLCNKA CLCNKB SLC35B1 SLCO1A2 SLC35B2 SLC35B4 CCS SCNN1G SCNN1B SCN5A SCNN1D SLC39A2 PLP2 GLRB SLC12A1 NOX5 SLC12A2 SLC12A3 SLC12A4 NOX1 SLC10A2 RHAG SLC10A1 SLC17A7 KCNN4 SLCO1B3 SLC17A5 SLC6A9 SLC17A3 SLC6A8 SLC17A4 SLC6A5 KCNN3 SLC17A1 SLCO1B1 SLC17A2 SLC6A6 KCNN2 SCN4B SLC5A6 SLC5A7 SLC14A1 SCN4A SLC14A2 | |
| STRUCTURAL_CONSTITUENT_OF_RIBOSOME http://www.broadinstitute.org/gsea/msigdb/cards/STRUCTURAL_CONSTITUENT_OF_RIBOSOME RPL18 MRPL41 RPL19 RPL14 RPL13 RPL15 RPLP2 RPS2 RPS3 RPS3A RPLP0 RPLP1 FAU RPL11 MRPL52 MRPL51 MRPS7 RPS4X RPS18 RPS19 RPS16 RPL41 RPS17 RPS14 RPS15 RPL3L RPS12 RPS4Y1 RPS13 RPS10 RPS11 MRPS14 MRPS12 RPL35 RPL27A RPS15A RPL37 RPL38 RPL39 RPS25 RPS26 MRPL10 RPL30 RPS27 MRPL12 RPS28 RPS29 RPL7 RPL31 RPL6 RPL34 RPL9 RPL8 RPL3 MRPL55 RPL5 RPL4 RPL7A RPS20 RPS21 RPS23 RPS24 MRPS22 MRPS24 RPL26 RPL27 RPS9 RPL24 RPL23A RPS6 RPS5 RPS8 RPL28 RPS7 RPL29 MRPL23 RPL18A RPL22 RPL13A RPL21 | |
| STEROID_DEHYDROGENASE_ACTIVITY_ACTING_ON_THE_CH_OH_GROUP_OF_DONORSNAD_OR_NADP_AS_ACCEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/STEROID_DEHYDROGENASE_ACTIVITY_ACTING_ON_THE_CH_OH_GROUP_OF_DONORSNAD_OR_NADP_AS_ACCEPTOR HSD3B2 HSD17B10 HSD3B1 HSD17B14 DHRS9 HSD17B4 HSD3BP4 HSD17B7 AKR1C1 NSDHL | |
| PROTEIN_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_KINASE_ACTIVITY EFNA3 CLK1 PRKX PRKY MAP3K7 MAP3K6 MAP3K5 MAP3K4 CLK3 CLK2 COL4A3BP WNK4 MAP3K9 MAP3K8 ILK TLK1 TLK2 MAP2K7 MAP2K6 TYRO3 BCR TNIK EFNB3 ROCK1 ROCK2 WNK1 PIM1 WNK3 WNK2 PIM2 MARK4 MARK1 MARK2 MAPK1 EIF2AK1 MAPK6 MAPK4 PDGFRL ROR1 PDGFRA MAPK9 ROR2 PDGFRB MAPK8 EFNA4 MST1R MAPK7 NEK4 EIF2AK2 EIF2AK3 NEK6 EIF2AK4 TAB1 CDK5R1 ERBB4 NEK2 ERBB3 ERBB2 STK17B CHEK2 STRADB PXK STK17A UHMK1 EPHB2 MUSK VRK1 EPHB6 VRK2 MAP2K1 TAOK2 TGFBR1 MAP2K3 TAOK3 NIM1 TGFBR2 TRIO DUSP21 OXSR1 ATM KDR EPHA5 CDC42BPG STRADA NTRK1 CDC42BPA TNK2 CDC42BPB NRP2 BCKDK ACVRL1 NRP1 NUAK2 LATS1 LATS2 CAMKK2 PDPK1 TGFA SIK3 TAF1L SRPK2 LYN CDK1 PHKG2 SRPK1 GTF2H1 MAST1 SIK2 RIPK1 MAP3K10 BRDT TXK MAP3K13 MAP3K12 MAP3K11 MKNK2 MKNK1 KIT SNRK PTK2B PDK1 CSNK1A1 PDK2 BRD2 PDK3 NLK PDK4 CSNK2B AXL TRIM27 MAPK11 MAPK10 RPS6KA5 TP53RK RPS6KA3 RPS6KA1 MAPK12 CSNK1D EPGN RPS6KA2 MAPK13 CSNK1E MAPK14 GSK3B MAPK15 CIT SIK1 ZAK STK38 STK36 RPS6KB2 TTK PRKCB TTN DMPK CSNK2A2 PRKACG CSNK2A1 PRKACB INSR EGFR TWF1 CSNK1G2 RPS6KC1 STK4 STK3 MAP4K3 MAP4K4 MAP4K5 CDKL1 TESK1 RIPK3 RIPK2 TESK2 RIPK4 KALRN PHKA2 STK16 FGFR1 FGFR4 CCL2 STK11 MAPKAPK5 STK10 PHKA1 PTK7 MAPKAPK3 MAP4K2 MAP4K1 MAPKAPK2 CCL4 IRAK3 PTK6 TEK LMTK2 DYRK2 STK19 STK38L CSF1R NR4A3 TAF1 ITK RYK MET SMG1 IKBKE PLK4 PLK3 ULK1 PLK1 DYRK1A CPNE3 MERTK MYLK PRKAG3 PRKAG1 PINK1 DDR2 SKAP1 ACVR1C AKT1 ACVR1B PAK2 CDK10 PAK1 TIE1 CHUK AKT2 IRAK2 IRAK1 SGK1 SGK2 LIMK2 SGK3 LIMK1 PRKCI CDK9 PRKCH MINK1 PRKCG PBK CDK7 PRKCE ALK DAPK2 CDK5 DAPK3 CDK2 NEK11 XRCC6BP1 GAK CDK3 PRKD1 TYK2 HUNK DDR1 ACVR2A ACVR2B CRKL HIPK3 IGF2R ERN1 ERN2 PRKD3 ACVR1 PRKCZ FRK BRSK2 BRSK1 TRIB2 TRIB1 EXOSC10 IGF1R MAP3K3 MAP3K2 CRIM1 FLT1 LTK FLT3 FLT4 TSSK1A TSSK2 TSSK4 TSSK3 TSSK6 | |
| MOLECULAR_ADAPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MOLECULAR_ADAPTOR_ACTIVITY RUSC1 FCRL2 ITSN2 SKAP2 SKAP1 SLA ARHGAP4 SHB ARHGAP6 ANK1 GAB1 ARHGAP1 SH3BGR CNTNAP1 SHC1 STAM FRS2 IRS4 KHDRBS1 SOCS2 SLA2 BAIAP2 TRAT1 SH2D3C SH2D2A GRB10 SH2D3A CRKL GRAP2 GRB14 SNX9 GRAP GRB2 ABI2 SRC SORBS2 SH2B2 BLNK VAV3 TP53BP2 LAT SH3BGRL EPS8 LASP1 CHN1 CHN2 GRB7 SH3BP2 TOB1 | |
| ADENYL_RIBONUCLEOTIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ADENYL_RIBONUCLEOTIDE_BINDING SIK1 STK38 ZAK STK36 TTN DMPK BTK MAP3K6 MAP3K5 NLRC4 DHX38 CLP1 WNK4 DDX25 VPS4A TLK1 TLK2 PRKACB EIF2B2 TWF2 MYO6 MYO3A ABCB11 WNK1 PIM1 OLA1 WNK3 WNK2 MYH9 STK4 MARK1 SARS2 CDKL5 STK3 MARK2 NVL MAP4K3 MAP4K4 MAP4K5 RFC1 RFC2 NME1 SMARCA5 NEK6 ME1 ABCA7 GCLC STK11 MAP4K2 STK17B MAP4K1 MYO9B ABCA2 PXK STK17A ABCA4 ABCA3 IRAK3 DYRK3 DYRK2 STK38L GABARAPL2 ABCB8 EPB42 PIF1 TGFBR1 NIM1 SPHK1 ABCB1 OXSR1 ABCB7 ABCB6 ABCG1 ABCG2 ATP7A TRNT1 CDC42BPG CDC42BPA TNK1 ABL1 ATP7B MYH10 PC CDC42BPB ABCF1 BCKDK ACVRL1 ABCF2 SEPHS1 NUAK2 PEX6 PINK1 MOV10L1 LATS1 LATS2 ACVR1B PEX1 SIK3 SRPK2 HSP90AA1 ACTA1 TP53 TPX2 PRKCI MINK1 CFTR DAPK2 DAPK3 NLRP1 SRPK1 NEK11 RAD51 DAPK1 EIF4A3 MAST1 SIK2 MAST2 ERN1 ERN2 DMC1 ACVR1 MKNK2 BRSK2 MKNK1 TRIB1 N4BP2 GALK1 ERCC6 SNRK DGKE CDK11A CDK11B TOR1A ABCD2 ABCD4 MSH6 PDS5B MSH2 NLK GSG2 APRT SMC4 RPS6KA5 ICK RPS6KA4 TSSK1A GCK ABCC3 HSPA4L DGKZ PPP2R4 ABCC1 TSSK2 TSSK4 PGK1 BMPR1B ABCC8 TSSK3 ABCC5 TSSK6 ABCC6 PGK2 BMPR1A | |
| EXOPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/EXOPEPTIDASE_ACTIVITY METAP1 AEBP1 METAP2 UCHL1 ANPEP ENPEP LNPEP ACE TPP1 CPA2 CPA3 ERAP1 ZMPSTE24 ERAP2 CPA1 DPEP1 DPP4 PEPD TRHDE METAP1D GGH NPEPPS XPNPEP1 BLMH CPE BACE1 ACE2 C9orf3 CPD PGCP CPB1 CPB2 | |
| UBIQUITIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/UBIQUITIN_BINDING CIITA UBE2N BCL10 NUP62 TOM1L1 DZIP3 SQSTM1 TSG101 UCHL1 TOP2A SIRT2 | |
| SUBSTRATE_SPECIFIC_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SUBSTRATE_SPECIFIC_CHANNEL_ACTIVITY KCNC1 KCNC4 KCNC3 AQP9 AQP8 AQP5 AQP7 CNGB1 AQP6 AQP2 CUL5 KCNK7 KCNK6 KCNK5 CHRNA4 MS4A2 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 CLCA2 KCND3 CLCA1 SCN2B CLCA4 PDPN SCN2A CNGA3 RYR3 RYR1 RYR2 KCNMB3 FXYD1 CLCN1 KCNMB4 ORAI1 FXYD3 CLCN3 SCN1B CLCN2 KCNA2 KCNA1 KCNA4 CACNB1 CACNB2 KCNA3 CACNB3 KCNA6 KCNA5 CACNB4 KCNJ3 KCNMB1 KCNJ1 KCNMB2 KCNS3 KCNS1 GAR1 ZACN SCN9A TRPC1 CACNA2D1 TRPC4 TRPC3 TRPC5 KCNB2 KCNK1 CACNA1S KCNK3 KCNK4 KCNJ5 P2RX5 KCNJ4 P2RX4 P2RX7 KCNJ6 SLC4A11 P2RX1 P2RX3 P2RX2 CACNA1G CHRNB4 CHRNB3 CACNA1H CACNA1E CHRND CHRNB2 CACNA1F CACNA1C CHRNE CACNA1D CLCN4 CACNA1A CACNA1B KCNK17 KCNH1 KCNJ15 KCNK15 GLRA1 TRPV1 TRPV2 GLRA2 KCNJ10 KCNJ12 KCNIP2 HVCN1 KCNJ14 KCNK10 KCNQ5 KCNQ3 CCT8L2 NMUR2 TRPV5 SCN7A TRPV6 KCNQ2 KCNQ1 KCNG2 TRPM5 CACNG5 CACNG4 CFTR CACNG2 CACNG1 STX1B TRPM2 TRPM1 KCNA10 BSND SCN11A KCNH2 KCNH3 KCNH4 SHROOM2 CLCNKA CLCNKB BEST1 KCNE1 PKD2 KCNE2 SCNN1G SCNN1B HTR3A HTR3B SCN5A SCNN1D GLRB NOX5 NOX1 KCNN4 ACCN1 ACCN4 KCNN3 KCNN2 SCN4B SCN4A | |
| ADENYL_NUCLEOTIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ADENYL_NUCLEOTIDE_BINDING SIK1 STK38 ZAK STK36 TTN BTK DMPK MAP3K6 NLRC4 MAP3K5 DHX38 WNK4 DDX25 CLP1 VPS4A TLK1 PRKACB TLK2 EIF2B2 TWF2 MYO6 MYO3A ABCB11 PIM1 WNK1 OLA1 WNK3 WNK2 MYH9 STK4 SARS2 CDKL5 MARK1 STK3 MARK2 MAP4K3 NVL MAP4K4 MAP4K5 RFC1 RFC2 NME1 SMARCA5 NEK6 ME1 ABCA7 GCLC STK11 MAP4K2 STK17B MAP4K1 MYO9B ABCA2 PXK STK17A ABCA4 ABCA3 IRAK3 DYRK3 DYRK2 STK38L GABARAPL2 ABCB8 EPB42 PIF1 TGFBR1 SPHK1 NIM1 ABCB1 OXSR1 ABCB7 ABCB6 ABCG1 ABCG2 TRNT1 ATP7A CDC42BPG CDC42BPA TNK1 CHST15 ABL1 ATP7B CDC42BPB PC MYH10 ABCF1 BCKDK ABCF2 SEPHS1 ACVRL1 NUAK2 PEX6 PINK1 PPOX MOV10L1 LATS1 LATS2 ACVR1B PEX1 SIK3 SRPK2 HSP90AA1 ACTA1 AIFM2 TPX2 PRKCI TP53 MINK1 CFTR DAPK2 DAPK3 NEK11 SRPK1 NLRP1 MTRR RAD51 DAPK1 EIF4A3 MAST1 MAST2 SIK2 ERN1 ERN2 DMC1 ACVR1 BRSK2 MKNK2 MKNK1 TRIB1 N4BP2 GALK1 ERCC6 DGKE SNRK CDK11A CDK11B TOR1A ABCD2 ABCD4 NOX4 MSH6 PDS5B MSH2 NLK GSG2 APRT SMC4 RPS6KA5 NDOR1 ICK RPS6KA4 TSSK1A GCK HSPA4L ABCC3 DGKZ ABCC1 TSSK2 PPP2R4 TSSK4 BMPR1B PGK1 TSSK3 ABCC8 TSSK6 ABCC5 BMPR1A ABCC6 PGK2 | |
| CYSTEINE_TYPE_PEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CYSTEINE_TYPE_PEPTIDASE_ACTIVITY SOLH PDIA3 LGMN UCHL1 CASP5 CASP6 CASP3 USP53 CASP9 CASP7 CASP8 USP12 USP11 CASP1 USP16 USP15 USP14 USP13 VCPIP1 CAPNS1 UFD1L USP1 CTSS SENP2 USP29 CTSK BLMH ATG4D ATG4C CAPN11 ATG4B CTSO ATG4A USP21 UCHL3 CTSB CTSH USP7 CTSL2 USP6 USP8 USP2 USP9Y USP5 USP9X USP4 CTSL1 CAPN6 CAPN5 CAPN9 CAPN3 TINAG CASP10 CASP14 | |
| HISTONE_DEACETYLASE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/HISTONE_DEACETYLASE_BINDING HDAC10 RAD9A KAT2B BCOR KAT2A TOP2B TOP2A SUDS3 SIRT2 HDAC6 | |
| SMALL_GTPASE_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SMALL_GTPASE_REGULATOR_ACTIVITY ALS2 PREX1 RAB3GAP1 RANGAP1 ARL2BP ARHGAP4 RCBTB2 ARHGAP5 GBF1 TIAM1 RAPGEF5 RANBP1 RAPGEF2 ERRFI1 ARHGEF3 ARHGEF2 ARHGEF1 RALBP1 MADD ARHGAP27 ARHGAP29 HERC1 PREX2 WAS FARP1 FARP2 ARHGEF11 THY1 IPO7 KRIT1 OPHN1 WASL ARHGDIG ARFGAP3 RUNDC3A MYO9B RCC1 RIMS1 ARFGEF1 ALDH1A1 RASAL2 RASAL1 CDC42EP2 DOCK2 RASGRP3 GMIP RASGRP4 SOS1 ARAP1 ARAP3 ARHGDIA RASA1 ARHGEF10L RASA2 ARHGDIB CYTH1 SERGEF CYTH2 GDI2 CYTH3 NF1 RALGDS DOCK4 DIS3 ADAP1 CYTH4 ARHGAP10 | |
| SMAD_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SMAD_BINDING FOXH1 ACVR1B EID2 ACVRL1 TGFBR1 SMAD4 SMAD3 TGFBRAP1 BMPR1B STUB1 ACVR1 BMPR1A | |
| ANTIGEN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ANTIGEN_BINDING IGHG1 IGHG2 IGHG3 IGHG4 SLC7A8 SLC7A9 IGHM IL7R SLC7A5 TAPBP LILRA1 LILRA2 ALB LILRA3 FCN2 MSLN FCN1 IGHA2 CHRNA7 LAG3 DHCR24 PPP2R1B PPP2R1A TOPORS SLAMF1 CD1D LILRB4 KIR2DL3 | |
| COFACTOR_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/COFACTOR_TRANSPORTER_ACTIVITY SLC22A16 HPX SLC6A8 SLC33A1 PDPN SLC22A4 SLC22A5 SLC19A1 ABCB7 SLC46A1 | |
| S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY DNMT3A LCMT1 RNMT EHMT1 PNMT SUV39H1 TPMT SUV39H2 PRMT7 PRMT8 TRDMT1 METTL1 BHMT WHSC1L1 AS3MT PEMT DNMT1 PCMT1 NSUN2 DNMT3B NSD1 NNMT FBXO11 | |
| HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDESCATALYZING_TRANSMEMBRANE_MOVEMENT_OF_SUBSTANCES http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDESCATALYZING_TRANSMEMBRANE_MOVEMENT_OF_SUBSTANCES ABCF1 ABCA8 FXYD2 ATP6V0E1 ATP1B1 ATP1B3 ATP1B2 ATP6V1B2 ABCA3 TAPBP ATP2B1 ATP6V0C ATP2B3 ATP2B4 ATP8B1 ABCD3 ABCD4 ATP4A ABCB11 ATP4B ATP11B ATP1A3 ATP1A4 ATP1A1 ATP1A2 ABCB7 ABCG1 ABCG2 ATP6V1C1 ATP7A ATP2A2 ATP2A3 ATP2C1 ATP2A1 ABCC3 ABCC1 ABCC2 ATP7B ABCC6 | |
| AMINE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/AMINE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC38A3 SLC44A1 SLC44A2 AQP9 SLC6A2 SLC6A3 SLC6A4 SLC7A8 SLC7A9 SLC7A4 SLC7A5 SLC7A6 SLC1A4 SLC1A5 SLC1A2 SLC1A3 SLC1A6 SERINC1 SLC1A7 SLC25A22 SLC22A3 SLC43A1 SLC1A1 OCA2 PDPN SLC6A14 SLC7A10 SLC3A1 SLC7A11 SLC25A12 SLC6A9 SLC25A13 SLC7A2 SLC6A5 SLC6A6 SLC18A2 SLC18A3 SLC18A1 SLC5A7 CTNS SLC25A15 | |
| CHAPERONE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CHAPERONE_BINDING VWF TSC1 TBCA TBCD TBCC PFDN4 TBCE HSPE1 HSPD1 SOD1 AHSA1 DNAJB6 | |
| ENZYME_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ENZYME_REGULATOR_ACTIVITY DLC1 ALS2 RAB3GAP2 SNCB PPP2R5B PPP2R5A PPP2R5D RAB3GAP1 RANGAP1 AGTR2 APP MAP3K5 GBF1 PPP1R1B PPP1R1A RAPGEF6 RAPGEF5 RAPGEF4 RAPGEF3 EIF2B2 GUCA2B RAPGEF2 EIF2B3 EIF2B4 TWIST1 EIF2B5 RECK IKBKAP DBNL F10 BCR SERPING1 PREX2 FARP1 SAG FARP2 THY1 SERPINF1 RFC1 PPP2R5E ATPIF1 EIF2AK2 CDK5R1 PPP2R3B SERPINA10 PPP2R3A PTPLAD1 RUNDC3A AFAP1L2 MYO9B RCC1 SERPINH1 RIMS1 ARFGEF1 PLAA CDC42EP2 HEXIM2 HEXIM1 DNMT3L ARAP1 ARAP3 PPP2R2B ARHGEF10L SPP2 ABR TAOK3 TRIO TPD52L1 PRPSAP1 SERPINI1 CAMK2N1 SERPINI2 PRPSAP2 RGS1 RGS2 RGS3 UBA2 RGS4 RGS5 PI3 RGS6 TNK2 RGS9 AHSA1 SPINK5 ARL2BP MMP24 GPX1 TRIAP1 CTAGE5 NOD1 SERPINA7 SERPINA6 SERPINA5 SERPINA4 SERPINA2 ERRFI1 ABCE1 ARHGEF3 ARHGEF2 ARHGEF1 AIFM3 CCKBR ANP32E MMP17 ARHGEF17 MMP16 MMP15 HERC1 WAS ARHGEF11 AMBP ANKRD27 SERPINB9 SERPINB6 BNIP2 SERPINB8 SERPINB7 SERPINB3 RAPGEFL1 CXCL1 RABGAP1 RAP1GAP RTKN SFN SET SOS1 AGT ALOX5AP PITRM1 SERPINB10 SERPINB12 CD24 THBS1 RASA3 RASA4 RASA1 CD27 RASA2 SERGEF CYTH1 GDI2 CYTH2 CYTH3 BIRC5 XIAP TRIM23 EIF2B1 PPP1R2 PPP1R7 PPP1R8 ADAP1 CHN2 MAT2B PPP2R4 CYTH4 IL2 DBF4 TNFSF14 IQGAP2 FGF13 RCVRN SAE1 MBIP IQGAP1 CXCL10 APOA4 RCBTB2 PRKAR2B APOA2 CDKN2A APOA1 LPA TIAM2 CASP8AP2 CDKN2B CDKN2C TIAM1 CDKN2D APOA5 DNAJC3 FRS2 DNAJC1 NET1 EGFR BCL10 MADD SOCS3 PKIG SOCS1 CST3 CST2 CST1 PKIA ADRM1 CST8 PLCE1 RENBP CST6 CST7 ARRB1 IGBP1 CST5 TNFAIP8 HSPB2 OPHN1 KALRN FGD2 ARHGDIG FGD1 EID1 FZR1 ARFGAP3 PPME1 SIPA1 APOC2 CDC42SE1 CTSA TIMP2 TIMP1 RASAL2 OAZ2 RASAL1 OAZ3 GCKR DOCK2 OAZ1 DOCK1 GMIP PRKRA LMTK2 FGD5 ANGPTL3 FGD6 ARHGDIA ANGPTL4 FGD4 ARHGDIB TESC CARD8 VAV3 MOB1B MALT1 PDE6H PDE6G DOCK4 CDKN1C HSPBP1 LCN1 CDKN1A CDKN1B PRKAR1A TSC2 PDZD3 DNAJB6 ARHGAP10 HSP90AB1 PREX1 ARHGAP4 ARHGAP5 CASP9 SPINT2 IPO5 RANBP1 CASP1 RHOH ELP4 ARL2 ARL1 ELP3 PPP2R1A HSP90AA1 BRCC3 RALBP1 ARHGAP27 SPINT1 ARHGAP29 PRKCD IPO7 KRIT1 GHRL WASL PROS1 PPP2R2A PPP1R12B CABP1 RNH1 STUB1 ALDH1A1 RGS11 RGS12 RASGRP3 RASGRP4 PTN SCG5 PIK3R1 GTF3C4 APC GUCA1B GPS1 GUCA1A FOXL2 GUCA1C PSAP NF1 RACGAP1 RGS16 ANXA5 RALGDS RGS14 ANXA2 GPS2 SH3BP5 GMFB DIS3 RGS20 GMFG MAPK8IP2 PDC FAF1 MAPK8IP1 IGFBP3 CSN2 | |
| RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITYENHANCER_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITYENHANCER_BINDING MYOD1 TFAP4 EPAS1 RELA MYF5 MYEF2 NFIX PURA HIF1A IRF8 RFX1 RFX3 NR5A2 ZFHX3 | |
| CYTOCHROME_C_OXIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CYTOCHROME_C_OXIDASE_ACTIVITY COX11 COX7A1 COX10 COX7B COX8A COX4I2 COX4I1 CYB5A COX7A2L COX5A COX5B SURF1 COX15 | |
| MONOCARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MONOCARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC16A2 SLC16A1 AKR1C4 SLC16A4 SLC16A7 SLC16A6 ABCB11 SLC16A8 SLC6A6 SLC10A2 SLC10A1 | |
| HELICASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/HELICASE_ACTIVITY XRCC5 SNRNP200 XRCC6 SETX IGHMBP2 DDX17 DDX18 DDX23 DHX38 DDX25 DDX21 DDX20 DDX10 G3BP1 RECQL EIF4A3 SMARCAL1 SMARCA5 RUVBL2 RUVBL1 SMARCA1 SMARCA2 SMARCA4 DDX39A SKIV2L INO80 ERCC8 ERCC6 DDX3X DHX15 CHD2 DHX16 CHD1 SUPV3L1 ERCC3 CHD4 DDX43 CHD3 ERCC2 RECQL4 DHX8 DHX9 UPF1 PIF1 DDX1 WRN DDX6 ATRX DDX56 RAD54B DDX54 | |
| OXIDOREDUCTASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY CYP3A4 LDHC ALDH8A1 LDHB CYP24A1 LDHA EHHADH PTGS1 OGDH BBOX1 GLDC PLOD2 PLOD3 PDHA2 WWOX TXNL1 NCF2 NCF1 CYP26A1 CYP1A2 DHDH UQCR11 TMX1 NNT TXNDC2 ALOX15B DLD SURF1 PRODH MDH1 HSD17B11 HSD17B10 ACADSB CYP1B1 HSD17B14 FDX1 TXN2 HADHA HADHB IDH1 ALDH4A1 GPD2 GCDH GPD1 CYP46A1 SCD MAOB FDXR HGD CYP7B1 CYP17A1 IPCEF1 CYP8B1 COX11 ENOX2 CYP2J2 COX10 CYP2C18 PDIA5 GPX2 NOS2 RDH8 MTHFD2 MSRA TYR NOS2P1 CYP39A1 P4HA2 FXN P4HA1 GPX4 GPX3 ALOX12B GSTZ1 NOS3 SARDH COX15 DHCR24 AIFM2 AIFM1 NDUFA13 CYB5A DECR1 GRHPR CBR3 GMPR ECSIT MTRR RDH5 HAO1 ALOX15 CYP27A1 H6PD HAO2 TXN CYBRD1 MECR DEGS1 ALOX12 HSD3B2 HSD3B1 TH UGDH COX7A2L CBR1 FMO1 DHCR7 FMO2 ETFDH HAAO HSD17B6 TSTA3 HSD17B4 QSOX1 ETFB HSD17B7 ETFA NSDHL BCKDHA NOS1 COX7A1 FADS1 BCKDHB SOD1 PHYH MSRB2 MSRB3 SOD2 SDHA GAPDHS BLVRA AOX1 SDHD BLVRB PHGDH CP HPGD ADH1B HSD3BP4 COX5A COX5B PDHB IDO1 VCL IDH3G CPOX MIOX AKR7A2 AKR7A3 CYGB DAO SPR LOX ASPH NQO1 HADH NQO2 ALDH6A1 NUDT5 QDPR CDO1 POR PYCR1 AKR1B10 XDH ME1 ME3 ME2 GLUD2 GLUD1 COX7B KMO PAH IVD CYP19A1 P4HB COX8A IDH3B CYB561 BCO2 DIO2 DOHH ALDH2 DIO1 CRYZL1 ACOX2 CYB5R3 CYB5R4 D2HGDH UQCRC1 CYB5R2 CYP11B1 CYP11B2 CYC1 DUOX2 PRDX4 PRDX2 PPOX PRDX3 MSMO1 ACOX3 NDUFS7 AKR1C3 HMOX2 GSR AKR1C2 TDO2 AKR1C4 NDUFS4 HMOX1 NDUFS8 SRD5A1 ACAD8 SRD5A2 CAT NDUFS3 LOXL2 IMPDH1 NDUFS2 AKR1C1 NDUFS1 IMPDH2 SUOX ACADM ALDH5A1 CYCS COX4I2 COX4I1 DHRS9 ALDH3B2 ACADL DDO ALDH3B1 ACADVL DHRS2 ALDH7A1 DHRS3 UQCRH CYP2A6 TXNRD2 TXNRD1 AOC2 ALDH9A1 SC5DL AOC3 ADH5 ADH6 EGLN2 EGLN1 ADH7 ALDH3A2 GLRX2 ALDH3A1 ALDH1A1 ALDH1A2 MTHFR AKR1A1 ADH4 ALDH1A3 EPX DMGDH BDH2 BDH1 APEX1 KDM4A GLRX NOX4 NOX5 NDUFA9 NOX1 tAKR MGST3 ADI1 RDH12 FRRS1 ABP1 RDH11 CYBA CYP4A11 CYP4F8 RDH10 L2HGDH AKR1B1 MPO CYP4F3 ALOX5 CYP4F2 RDH16 RETSAT | |
| DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY KCNS3 KCNH1 KCNS1 KCNB2 KCNA2 KCNA1 KCNE1 KCNA3 KCNA5 KCNH2 KCNQ1 KCNG2 | |
| KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/KINASE_ACTIVITY EFNA3 CLK1 PRKX PRKY MAP3K7 MAP3K6 MAP3K5 MAP3K4 CLK3 CLK2 COL4A3BP MAP3K9 WNK4 MAP3K8 ILK PIK3C3 PIK3CA TLK1 TLK2 MAP2K7 MAP2K6 PIK3CG TYRO3 TNIK BCR ROCK1 EFNB3 ROCK2 PIK3CB WNK1 PIM1 WNK3 PIM2 WNK2 MARK4 MARK1 NME6 MARK2 NME4 NME5 PNKP MAPK1 NME2 EIF2AK1 MAPK6 NME1 MAPK4 PDGFRL ROR1 PDGFRA MAPK9 PDGFRB ROR2 MAPK8 MST1R MAPK7 EFNA4 NEK4 EIF2AK2 EIF2AK3 NEK6 EIF2AK4 COASY TAB1 CHKA CDK5R1 ERBB4 ERBB3 NEK2 ERBB2 PFKFB2 PFKFB1 STK17B PXK STRADB CHEK2 STK17A TK2 UHMK1 EPHB2 TK1 MUSK VRK1 EPHB6 VRK2 MAP2K1 TAOK2 TGFBR1 MAP2K3 NIM1 TGFBR2 SPHK1 TAOK3 TRIO DUSP21 OXSR1 ATM KDR EPHA5 STRADA CDC42BPG CKMT1A NTRK1 CDC42BPA TNK2 CDC42BPB NRP2 BCKDK ACVRL1 NRP1 NUAK2 ARSG PMVK LATS1 LATS2 CKB CAMKK2 PDPK1 FXN SIK3 TGFA TAF1L SRPK2 LYN CDK1 PIK3C2A PHKG2 PI4KA DGUOK PI4KB SRPK1 GTF2H1 MAST1 SIK2 CKM ADK RIPK1 MAP3K10 BRDT TXK MAP3K13 MAP3K12 MAP3K11 PIKFYVE CMPK1 MKNK2 HK2 MKNK1 HK1 KIT GALK2 DGKA GALK1 SNRK DGKE PTK2B DGKD DGKG CKMT2 CERK PDK1 CSNK1A1 PDK2 BRD2 DGKQ PDK3 NLK PDK4 CSNK2B AXL TRIM27 DGKK MAPK11 NADK MAPK10 DGKI RPS6KA5 KHK TP53RK RPS6KA3 CSNK1D MAPK12 RPS6KA1 MAPK13 EPGN RPS6KA2 CSNK1E GSK3B MAPK14 MAPK15 DGKZ CIT PGK1 TJP2 PGK2 SIK1 STK38 ZAK STK36 DTYMK CASK RPS6KB2 TTK ITPKB TTN PRKCB ITPKA DMPK CSNK2A2 PRKACG CSNK2A1 PRKACB INSR EGFR TWF1 PDXK MTOR CSNK1G2 RPS6KC1 STK4 STK3 MAP4K3 MAP4K4 MAP4K5 CDKL1 PI4K2A RIPK3 TESK1 RIPK2 TESK2 MVK RIPK4 PRPS2 KALRN PRPS1 PHKA2 STK16 FGFR1 FGFR4 CCL2 GNE STK11 MAPKAPK5 STK10 PHKA1 MAP4K2 PTK7 MAPKAPK3 MAP4K1 MAPKAPK2 CCL4 IRAK3 PTK6 TEK LMTK2 DYRK2 STK19 STK38L CSF1R NR4A3 ITK TAF1 RYK AK1 MET SMG1 AK2 AK5 GLYCTK IKBKE PLK4 PLK3 PLK1 ULK1 DYRK1A CPNE3 MERTK GUK1 MYLK PIP4K2B PRKAG3 PRKAG1 PINK1 SKAP1 DDR2 ACVR1C AKT1 ACVR1B PAK2 CDK10 PAK1 TIE1 DLG2 CHUK DLG1 AKT2 IRAK2 IRAK1 SGK1 SGK2 PFKL LIMK2 MPP1 SGK3 LIMK1 MPP2 MPP3 PFKP PRKCI MINK1 PRKCH CDK9 PRKCG PBK PFKM CDK7 PRKCE ALK DAPK2 CDK5 DAPK3 CDK2 NEK11 XRCC6BP1 GAK CDK3 PRKD1 TYK2 DDR1 HUNK ACVR2A ACVR2B CRKL PKM2 HIPK3 IGF2R PKLR ERN1 ERN2 PRKD3 ACVR1 XYLB PRKCZ FRK DCK BRSK2 BRSK1 TRIB2 TRIB1 N4BP2 EXOSC10 IGF1R MAP3K3 MAP3K2 ETNK1 PIK3R3 CRIM1 PIK3R2 LTK FLT1 FLT3 FLT4 TSSK1A GCK TSSK2 IPPK TSSK4 TSSK3 TSSK6 | |
| PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY F2RL2 CASR PDE3B PTPN22 PTPN21 CNP PDE4A NT5C3 NT5C2 PDE4B BPNT1 NANP PTPRJ PLD3 PTPRK PLD2 PLD1 PTPRM PTPRF PTPRG PTPRH PTPRN2 PTPRR FBP1 PTPRS PTPRT PDE4D PDE4C PTPRU FBP2 PTPRN PTPRO TPTE PNKP PLCE1 PPP1CA CCR5 PPP5C C3AR1 ENPP7 PPP2R3B ENPP2 ACP6 ENPP3 PFKFB1 ACP5 ACP2 DUSP12 DUSP11 BDKRB2 OCRL ACP1 PPP1R3D PPP1R3C DUSP13 PTPLA PLCH1 CTDNEP1 INPP5K PTPN7 PTPN6 PTPN9 PTPN18 PTPN3 PTPN2 PTPN5 EPM2A PTPN4 PTPN14 PTPN12 PTPN11 PDE7B PDE7A PTPN1 IMPA2 IMPA1 PDIA3 CDC14B SYNJ1 TIMM50 PSPH PTEN EDNRA DLGAP5 NT5E PLCB2 DLG1 NT5C MINPP1 CCKBR PPAP2C PGAP1 CYCS CILP APTX PDE10A PPM1G CHRM5 G6PC PPM1D MTMR14 SBF1 PPEF2 CHRM3 PPEF1 CHRM1 LCK INPP4B PPM1M CTDP1 PPP2R2A INPP1 PPP6C PPM1A PPM1B MTMR2 MTMR3 PSPHP1 PDE1B PDE1C PPP2CB PDE1A INPP5E PLCD1 INPP5D PPAP2A APEX1 MTMR7 PPAP2B PTPRB GDE1 PTPRC PTPRD PTPRE PTPRZ1 PTPRA PDE3A CDKN3 CDC25B DUSP5 DUSP4 DUSP3 DUSP2 DUSP1 PTP4A3 PDE2A PTP4A2 SMPD1 DUSP8 SMPD4 DUSP7 SMPD2 DUSP6 | |
| SUBSTRATE_SPECIFIC_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SUBSTRATE_SPECIFIC_TRANSPORTER_ACTIVITY CDIPT SLC9A7 SLC9A6 SLC9A5 SLC9A3 SLC9A2 CUL5 KCNK7 KCNK6 KCNK5 CLCA2 CLCA1 SCN2B CLCA4 PDPN SCN2A GLTP PITPNM1 NPC1 PITPNM3 ADAMTS8 RYR3 RYR1 RYR2 SURF1 ORAI1 SCN1B CACNB1 CACNB2 CACNB3 CACNB4 KCNJ3 KCNJ1 SLC29A1 ATP6V0C SLC29A2 SLC28A2 ATP11B KCNK1 KCNK3 KCNK4 KCNJ5 KCNJ4 APOL3 KCNJ6 APOL1 LASP1 CHRND CHRNE SLC9A1 KCNK17 KCNH1 KCNK15 GLRA1 SLC20A1 TRPV1 SLC20A2 TRPV2 GLRA2 KCNK10 SLC23A1 CFHR4 SLC23A2 NMUR2 TRPV5 SLC22A4 SLC22A3 CETP SLC22A6 TRPV6 SLC22A2 KCNG2 SLC22A1 SLC22A7 SLC22A8 CACNG5 SLC3A2 CACNG4 CFTR CACNG2 SLC3A1 CACNG1 SCN11A KCNH2 KCNH3 KCNH4 CCT6B PKD2 KCNE1 KCNE2 HSD17B4 HTR3A HTR3B SLC8A1 TRAPPC10 PLSCR1 ACCN1 ACCN4 LRP1 CTNS KCNC1 KCNC4 KCNC3 XPO6 SLC7A8 SLC7A9 SLC7A4 SLC7A5 SLC7A6 SLC2A8 APOA4 SLC2A5 APOA1 SLC2A4 SLC2A3 SLC2A2 SLC2A1 PITPNC1 KCND3 PCTP SLC34A1 SLC34A3 SLC34A2 NGB SLC40A1 KCNA2 KCNA1 KCNA4 KCNA3 KCNA6 KCNA5 ABCA1 SLCO2A1 APOC4 ZACN SCN9A CACNA2D1 KCNB2 SLC6A14 ANKH CACNA1S ATP7A P2RX5 P2RX4 P2RX7 P2RX1 SLC7A2 P2RX3 P2RX2 CACNA1G SLC13A2 CACNA1H CACNA1E CACNA1F SLC13A4 CACNA1C CACNA1D CACNA1A CACNA1B ATP7B SLC1A4 SLC1A5 SLC1A2 AKR1C4 SLC1A3 ZFYVE16 SLC1A6 SLC1A7 SCN7A SLC43A1 SLC1A1 OCA2 TRPM5 SLC7A10 IPO9 SLC7A11 TRPM2 TRPM1 UQCRH CLCNKA CLCNKB SLC35B1 SLCO1A2 SLC35B2 SLC35B4 CCS SCNN1G SCNN1B SCN5A SCNN1D PLP2 SLC12A1 NOX5 SLC12A2 SLC12A3 SLC12A4 NOX1 SLCO1B3 HBZ SLCO1B1 SCN4B HBE1 SLC14A1 SCN4A SLC14A2 ATP1B1 ATP1B3 AQP9 AQP8 ATP1B2 PITPNA AQP5 AQP7 AQP6 SLC35A1 AQP1 SLC35A2 SLC35A3 AQP2 ATP2B1 ATP2B3 ATP2B4 APOD APOF CHRNA4 CHRNA7 CHRNA6 CHRNA1 APOM CHRNA3 CHRNA2 SLC12A7 SLC12A9 ABCB11 NNT RHCG PPBP ATP2C1 CLCN1 KCNMB3 KCNMB4 CLCN3 CLCN2 KCNMB1 KCNMB2 SLC11A2 SERINC1 SLC31A2 SLC31A1 TRPC1 TRPC4 TRPC3 TRPC5 ABCG1 ATP2A2 ATP2A3 ATP2A1 CHRNB4 CHRNB3 CHRNB2 CLCN4 KCNJ15 COX11 ATP6V0E1 SLC15A1 SLC15A2 COX10 TSNAX GJA1 KCNJ10 KCNIP2 HVCN1 KCNJ12 KCNJ14 FXN SLC25A3 SLC25A1 COX18 COX15 ATP4A SLC25A4 SLC25A5 ATP4B CYB5A STX1B ATP6V1C1 KCNA10 SLC26A4 BSND SLC27A4 CLDN16 SHROOM2 COX7A2L SLC19A2 BEST1 EIF4ENIF1 COX7A1 ATP1A3 ATP1A4 ATP1A1 ATP1A2 ITPR3 ITPR1 ITPR2 COG3 SLC16A2 SLC16A4 SLC16A7 SLC16A6 SLC16A8 ABCC3 ABCC2 ABCC8 ABCC5 COG1 COG2 SLC22A13 SLC6A2 SLC22A12 SLC22A14 SLC22A11 SFTPA1 CNGB1 COX5A COX5B TAPBP SLC16A1 SLC25A22 MS4A2 SLC4A2 SLC4A1 SLC4A4 SLC4A3 CNGA3 SEC61B FXYD1 FXYD2 FXYD3 SLC38A3 MCL1 COX7B ATP6V1B2 KCNS3 KCNS1 GAR1 SLC30A4 SLC30A5 SLC30A3 COX8A SLC25A12 SLC25A11 SLC4A11 SLC25A13 SLC25A10 SLC25A19 ASNA1 SLC25A15 SLC5A3 SLC5A2 SLC5A5 UQCRC1 SLC5A1 KCNQ5 KCNQ3 CCT8L2 ATP8B1 KCNQ2 KCNQ1 RAMP1 COX4I2 COX4I1 SLC37A4 SLC39A2 GLRB SLC10A2 RHAG SLC10A1 SLC17A7 KCNN4 SLC6A9 SLC17A5 SLC17A3 SLC17A4 SLC6A8 SLC6A5 KCNN3 SLC17A1 KCNN2 SLC6A6 SLC17A2 SLC5A6 SLC5A7 | |
| SPECIFIC_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SPECIFIC_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY HDAC5 NKRF EID1 BMP2 CREBZF PHB2 HDAC10 ZBTB16 HDAC9 HDAC7 UBP1 HDAC6 | |
| METALLOEXOPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/METALLOEXOPEPTIDASE_ACTIVITY METAP1 PEPD METAP2 METAP1D ENPEP CPA2 ERAP1 CPA3 ZMPSTE24 PGCP CPA1 CPB2 DPEP1 | |
| KINASE_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/KINASE_REGULATOR_ACTIVITY ALS2 CDK5R1 FGF13 AFAP1L2 MBIP SFN CXCL10 PRKAR2B AGTR2 CDKN2A CDKN2B HEXIM2 HEXIM1 CDKN2C PPP1R1B CDKN2D CD24 DNAJC3 PIK3R1 RHOH APC ELP4 IKBKAP BCL10 ELP3 CCKBR SOCS3 MADD SOCS1 TAOK3 PKIG MOB1B MALT1 PKIA CAMK2N1 SH3BP5 CDKN1C GMFB CDKN1A CDKN1B GMFG PRKAR1A MAPK8IP2 GHRL MAPK8IP1 IL2 | |
| OXIDOREDUCTASE_ACTIVITY_GO_0016706 http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_GO_0016706 P4HB P4HA2 P4HA1 PLOD2 PLOD3 EGLN2 EGLN1 ASPH KDM4A BBOX1 | |
| PEPTIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PEPTIDE_BINDING F2RL2 OPRM1 MCHR1 F2RL3 CCKAR OPCML TACR3 TACR2 TACR1 SLC7A8 SLC7A9 SLC7A5 SSR1 PEX7 TAPBP AGTR2 KISS1R GALR1 NMUR1 ANG MRGPRX2 GALR3 NMUR2 GALR2 MC5R XCR1 KDELR1 KPNB1 INSR TOMM34 DHCR24 KDELR2 C5AR1 CCKBR CMKLR1 NPBWR1 NPBWR2 NKTR SSTR4 SSTR5 SSTR2 SSTR3 SSTR1 MC2R GPR17 KPNA3 KPNA2 KPNA1 CALCR C3AR1 AVPR2 OPRK1 FPR1 NFKBIA OXTR BDKRB1 NPY6R BDKRB2 HCRTR2 MSLN MAS1 GRPR GP1BA MC3R TNPO2 TNPO1 PIK3R1 BRS3 CXCR2 PPIE PPIH PPIG PPID AVPR1B PPIC BRE AVPR1A FPR3 MC4R FPR2 NMBR SSR2 F2R OPRD1 SSR3 | |
| ADP_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ADP_BINDING ME1 MSH6 MYO6 GCLC MYO3A ACTA1 MSH2 MYO9B MYH9 ABCG1 MYH10 | |
| NUCLEOTIDYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NUCLEOTIDYLTRANSFERASE_ACTIVITY PTGES3 COASY POLR2E POLR2L POLR2J POLR2I POLA1 MED21 POLR2D RNGTT PRIM1 POLE4 DKC1 DNTT POLE2 POLE3 PRIM2 THG1L PCYT1A POLG2 PCYT1B PAPSS1 PCYT2 POLQ PAPSS2 TERT USP14 POLR3G UAP1 POLR3H POLI POLH POLR3K POLG POLE POLR1C POLB POLR3C TRNT1 POLRMT POLD4 POLD1 TEP1 CTDP1 UGP2 NMNAT1 REV3L | |
| CHEMOKINE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CHEMOKINE_ACTIVITY CXCL1 CCL1 CCL3 CCL2 CXCL5 CXCL3 CXCL2 C5 CXCL9 CCL8 PF4 CXCL6 CX3CL1 CCL5 CXCL11 CXCL12 CCL28 CCL4 CCL27 CCL7 CXCL10 CCL26 CCL24 CCL25 CCL22 CCL23 CCL20 CCL21 CKLF IL8 CCL19 CCL16 CCL15 CCL18 CCL17 CCL11 CCL13 CXCL14 CXCL13 CXCL16 XCL1 XCL2 | |
| PROTEIN_N_TERMINUS_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_N_TERMINUS_BINDING NBN HAX1 EIF5A KCNIP2 DAXX CSNK2A2 PGR ERCC5 ERCC6 CSNK2A1 PEX14 ERCC3 ERCC4 NR1H4 GLRX ERCC2 NFE2 RELA SLA2 TP53 ESR1 APTX GTF2H3 DCTN4 GTF2H2 ATM VWF MNAT1 NCOA1 SMARCE1 TSC1 NCOA3 ZWINT SMARCC1 CALM3 SDCBP PARP1 SMARCA4 | |
| PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY CLK1 PRKX PRKY MAP3K7 MAP3K6 MAP3K5 MAP3K4 CLK3 CLK2 MAP3K9 WNK4 ILK MAP3K8 TLK1 TLK2 BCR TNIK ROCK1 ROCK2 PIM1 WNK1 WNK3 WNK2 PIM2 MARK4 MARK1 MARK2 MAPK1 EIF2AK1 MAPK6 MAPK4 MAPK9 MAPK8 MAPK7 NEK4 EIF2AK2 EIF2AK3 NEK6 EIF2AK4 NEK2 STK17B STK17A CHEK2 UHMK1 VRK1 VRK2 TAOK2 TGFBR1 TAOK3 TGFBR2 NIM1 TRIO OXSR1 ATM CDC42BPG CDC42BPA CDC42BPB BCKDK ACVRL1 NUAK2 LATS1 LATS2 PDPK1 SIK3 TAF1L SRPK2 CDK1 PHKG2 SRPK1 GTF2H1 MAST1 SIK2 RIPK1 MAP3K10 BRDT MAP3K13 MAP3K12 MAP3K11 MKNK2 MKNK1 SNRK CSNK1A1 BRD2 NLK CSNK2B MAPK11 MAPK10 RPS6KA5 TP53RK RPS6KA3 MAPK12 RPS6KA1 CSNK1D MAPK13 RPS6KA2 CSNK1E MAPK14 GSK3B MAPK15 CIT SIK1 ZAK STK38 STK36 RPS6KB2 TTK TTN PRKCB DMPK CSNK2A2 PRKACG CSNK2A1 PRKACB CSNK1G2 RPS6KC1 STK4 STK3 MAP4K3 MAP4K4 MAP4K5 CDKL1 RIPK3 TESK1 TESK2 RIPK2 RIPK4 KALRN STK16 PHKA2 STK11 MAPKAPK5 STK10 PHKA1 MAP4K2 MAP4K1 MAPKAPK2 IRAK3 LMTK2 DYRK2 STK19 STK38L TAF1 SMG1 IKBKE PLK4 PLK3 PLK1 ULK1 DYRK1A CPNE3 MYLK PRKAG3 PRKAG1 PINK1 ACVR1C AKT1 ACVR1B PAK2 CDK10 PAK1 CHUK AKT2 IRAK2 IRAK1 SGK1 SGK2 SGK3 LIMK2 LIMK1 PRKCI CDK9 MINK1 PRKCH PRKCG CDK7 PBK DAPK2 PRKCE DAPK3 CDK5 CDK2 NEK11 XRCC6BP1 CDK3 GAK PRKD1 HUNK ACVR2A ACVR2B HIPK3 ERN1 ERN2 PRKD3 ACVR1 PRKCZ BRSK2 BRSK1 EXOSC10 MAP3K3 MAP3K2 TSSK1A TSSK2 TSSK4 TSSK3 TSSK6 | |
| RNA_POLYMERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RNA_POLYMERASE_ACTIVITY POLR3G POLR3H POLR2E POLR3K POLR2L POLR2J POLR2I POLA1 POLR1C MED21 POLR2D POLR3C PRIM1 POLRMT PRIM2 CTDP1 | |
| HISTONE_ACETYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/HISTONE_ACETYLTRANSFERASE_ACTIVITY ELP4 TAF1 TAF5 CREBBP HAT1 BRCA2 EP300 NCOA3 EDF1 KAT7 KAT8 SRCAP GTF3C4 KAT6B TAF1L KAT6A | |
| OXYGEN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/OXYGEN_BINDING CYP3A4 NOX4 CYP3A5 CYP3A7 CYP2F1 CYP1B1 CYP1A1 CYP2C19 CYP11A1 CYP2C18 EGLN2 CYP26A1 CYP1A2 CYP2E1 CYP4B1 CYP17A1 ALB CYP2A6 CYP2A7 CYP8B1 HBB CYP19A1 | |
| RNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/RNA_BINDING HNRNPK RPL18 RPL19 DZIP3 RPL14 RPL13 HNRNPF SURF6 RPL15 RNASEH1 RPLP2 SYNCRIP ZNF638 SRSF4 DDX17 RAE1 RPLP0 RPLP1 LSM5 FAU LSM1 AARS PTBP1 NOP56 PPARGC1A SRSF3 RPS19 PTRF RPS17 SERBP1 RPS14 ZNF239 EIF2S2 RPS12 RPS13 RPS10 GEMIN2 EIF2AK2 FUS NHP2L1 FARS2 PABPC4 IGF2BP2 DUSP11 IGF2BP3 RPS25 RPS26 SNRNP40 RPS27 RPS29 HEXIM2 HEXIM1 TRA2B PABPC3 SUPV3L1 RPS20 PABPC1 RPS21 HNRNPH2 HNRNPH1 RPS23 RPS24 RTCD1 PAIP1 CELF1 CELF2 NXF5 FXR2 RPS6 RPS5 RPS8 HNRNPA0 RPS7 FXR1 OASL RPL18A POP4 CWC15 EIF2A ZNF346 AUH PARN JAKMIP1 ZFP36 MRPL3 EXOSC7 ACO1 SNUPN RBM45 EXOSC2 SF1 APTX HNRPDL EIF4A3 RPL41 ROD1 EIF4A1 RPL3L NOP14 RPL27A RPL35 NUFIP1 RPL38 RPL39 SF3B4 KIN SF3B3 STAU2 NUFIP2 STAU1 RPP14 ZFP36L1 RPL30 MRPL12 RPL31 DDX19B RPL34 SEPSECS DAZL BCAS2 DAZ2 SNRNP70 RPL26 RPL24 ILF3 ELAVL2 ELAVL4 ETF1 RPL28 SF3A3 RPL29 MRPL23 ILF2 PPP1R8 RPL22 RPL21 TXNL4A BARD1 HNRNPAB RALY APOBEC2 NCBP1 SRP14 RNASEL RNMT APOBEC1 RBM3 RBM4 RBM5 SNRPD1 RBM6 EIF5A TLR3 APOBEC3G RBFOX2 APOBEC3F TLR7 TLR8 SMNDC1 TLR9 DDX23 TIA1 RBMS2 SRRM1 PABPN1 CARS HNRNPUL1 HNRNPA2B1 FMR1 NR0B1 HNRNPR HNRNPU HNRNPA3 PSMA1 RBPMS TIAL1 RBMY2BP SLU7 AKAP1 DAZAP1 HNRNPL CWC22 NHP2 TROVE2 RPL7 RPL6 RPL9 NPM1 RPL3 AIMP1 RPL7A RPL4 DDX43 EWSR1 NOVA1 XPOT CSTF3 CSTF2 IREB2 RNPS1 SSB EIF4B RBMY1A1 TRNT1 PPIE EIF4E EIF4H CIRBP CSTF1 EIF4E2 DICER1 MOV10L1 MKI67IP RPS2 RPS3 DKC1 RPS3A PCBP4 ANG PCBP1 PCBP2 LRRFIP1 NOL6 KHDRBS1 NOL4 NOL3 SARS PRPF3 MRPS7 MBNL1 NCL PURB TARBP1 TARBP2 EIF4G3 KHSRP CPSF6 CPSF1 SRSF10 RPS15A ADAT1 A1CF PRPF8 NUDT21 MSI1 SCAF11 GEMIN5 AGFG1 RAD51AP1 ADARB2 GRSF1 RCAN3 CELF4 FBL SLBP ATXN1 HSP90B1 ZRANB2 TEP1 | |
| N_METHYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/N_METHYLTRANSFERASE_ACTIVITY EHMT1 RNMT PNMT SUV39H1 SUV39H2 PRMT1 PRMT7 PRMT8 WHSC1L1 PEMT NSD1 FBXO11 NNMT | |
| GABA_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GABA_RECEPTOR_ACTIVITY GABRR2 GABRD GABRE GABRA1 GABRR1 GABRB3 GABRB2 GABRB1 GABBR1 GABBR2 GABRP | |
| NEUROTRANSMITTER_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/NEUROTRANSMITTER_BINDING CCKAR MCHR1 TSPO TACR3 TACR2 TACR1 KISS1R GALR1 NMUR1 MRGPRX2 GALR3 NMUR2 GALR2 CHRNA5 CHRNA4 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 GABRG2 CCKBR SSTR4 SSTR5 CHRM5 SSTR2 ADRB2 CHRM4 SSTR3 CHRM3 SSTR1 CHRM2 CHRM1 MC2R DRD1 DRD3 DRD2 DRD5 DRD4 NPY6R HCRTR2 ADRB3 ANXA9 GABRA2 GABRA4 GABRA3 GABRA6 BRS3 CHRNB4 CHRNB2 CHRNB1 NMBR CHRNE | |
| 3_5_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/3_5_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY PDE3B PDE4D PDE3A PDE10A PDE4C PDE7B PDE1B PDE2A PDE7A PDE1C PDE4A PDE4B PDE1A | |
| STEROID_HORMONE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/STEROID_HORMONE_RECEPTOR_ACTIVITY PPARD AR NR3C2 NR3C1 NR4A3 ESR2 NR2E1 NR2C1 PGR NR1I3 NR1D1 PGRMC2 NR2F6 | |
| NUCLEOSIDE_TRIPHOSPHATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NUCLEOSIDE_TRIPHOSPHATASE_ACTIVITY XRCC5 ATP1B1 ATP1B3 ATP1B2 XRCC6 RAB1A ATP2B1 ATP2B3 DDX17 ATP2B4 DDX18 DIRAS3 DHX38 RAB28 VPS4B GNG3 RAB27B RAB27A GTPBP2 GTPBP4 OPA1 RAN ABCB11 NCF1 EIF2S3 MYH7 MYH6 MYH9 RND2 RND3 RFC3 ATP2C1 SMARCAL1 AGAP2 RAB13 GNAI3 GNAI2 GNAI1 ARF6 MYO9B ARF5 ATP6V0C THTPA RAC2 RAC3 RAC1 DHX8 DHX9 ATP11B RAB7L1 ABCG1 ABCG2 RERG GNGT1 ARF1 ATP2A2 ATP2A3 ARF3 ATP2A1 ARF4 CCT8 RHEB RAD54B GNAZ ABCF1 ATP6V0E1 RAB5B RAB5C RAB6A TOP2A RAP2A RBBP4 ATP4A ATP4B RAB4A TTF2 RAD51 ATP6V1C1 EIF4A3 GNAL GNAQ GNB2 GNB1 RAB5A RUVBL2 GNAS GNB3 RUVBL1 ARL4D ARL4C RASD1 ARL4A RAB3A RAB3B RAB3D WRNIP1 SKIV2L GNG11 INO80 RAB11B ABCD3 ABCD4 RAB2A UPF1 ATP1A3 ATP1A4 ATP1A1 ATP1A2 TRIM23 RAB31 RAB30 GNG10 RAB35 RAB22A ABCC3 KIF20B ABCC1 PPP2R4 ABCC2 DNM1 ABCC6 SEPT5 GNA13 SEPT4 GNA14 GNA15 RAB9A GNA11 GNA12 SNRNP200 EIF5 RRAD TAPBP DDX23 DDX25 RRAS DDX21 DDX20 MX2 NUDT1 MYO3A EFTUD2 PICK1 CLPX SMARCA5 SMARCA1 DDX39A SEPT9 MYL6 ABCA8 RAB7A FXYD2 MRAS ARFRP1 KATNB1 ABCA2 ATP6V1B2 ABCA3 RRAGC DDX3X KATNA1 RAB6C DDX43 PIF1 MYO1E ABCB7 RAB33A ATP7A PSMC6 DDX56 PSMC5 PSMC4 VCP PSMC1 RAP1A DDX54 MYH10 ATP7B RSF1 PEX6 CDC42 ARHGAP5 PEX1 RASL10A RHOA ATP8B1 RHOB RHOC RHOD RHOG ARL1 RALBP1 G3BP1 RECQL KIF1B BPTF RRAS2 ERCC8 ERCC6 CHD2 CHD1 TGM3 ERCC3 CHD4 CHD3 MSH6 GNAO1 DNM1L MSH2 RABL2A RABL2B GSPT1 | |
| CARBOXYPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBOXYPEPTIDASE_ACTIVITY BLMH AEBP1 PEPD CPE CPA2 ACE2 CPA3 PGCP CPA1 CPD CPB1 CPB2 | |
| NEUROTRANSMITTER_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NEUROTRANSMITTER_RECEPTOR_ACTIVITY CCKAR MCHR1 TSPO TACR3 TACR2 TACR1 KISS1R GALR1 NMUR1 NMUR2 GALR3 GALR2 CHRNA5 CHRNA4 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 GABRG2 CCKBR SSTR4 SSTR5 CHRM5 SSTR2 SSTR3 CHRM4 CHRM3 CHRM2 SSTR1 CHRM1 MC2R DRD1 DRD3 DRD2 DRD5 DRD4 NPY6R HCRTR2 ANXA9 GABRA2 GABRA4 GABRA3 GABRA6 BRS3 CHRNB4 CHRNB2 CHRNB1 NMBR CHRNE | |
| INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY PTGES3 HSD3B2 P4HB EBP GNPDA1 HSD3B1 PDIA3 PDIA2 ERP29 PDIA6 PDIA5 DCT ERP44 TPI1 MPI PTGIS PTGDS DDT IDI1 | |
| N_ACYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/N_ACYLTRANSFERASE_ACTIVITY ELP4 SAT1 TAF1 TAF5 NAT1 CREBBP NAT2 HAT1 BRCA2 CERS5 EP300 ALAS2 SMARCE1 NCOA3 CERS1 AANAT EDF1 KAT7 KAT8 SRCAP GTF3C4 KAT6B KAT6A TAF1L | |
| ANION_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ANION_CHANNEL_ACTIVITY CLCN1 FXYD1 GLRB CLCA2 FXYD3 CLCN3 CLCA1 CLCN2 CLCA4 GLRA1 GLRA2 CLCNKA CLCNKB CFTR BSND BEST1 CCT8L2 NMUR2 PKD2 CLCN4 | |
| PROTEIN_KINASE_INHIBITOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_KINASE_INHIBITOR_ACTIVITY SOCS3 PKIG SOCS1 TAOK3 SFN MBIP PKIA CAMK2N1 CDKN1C SH3BP5 GMFB CDKN1A AGTR2 CDKN1B CDKN2A CDKN2B HEXIM2 PPP1R1B HEXIM1 GMFG CDKN2C CDKN2D MAPK8IP1 DNAJC3 | |
| METHYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/METHYLTRANSFERASE_ACTIVITY RNMT PNMT EZH2 MGMT PRMT1 PRMT7 PRMT8 ATIC PRMT5 METTL1 TRDMT1 PEMT EED GCSH PCMT1 DNMT3B NSUN2 DNMT3A LCMT1 EHMT1 SUV39H1 TPMT SUV39H2 GART SUZ12 COQ3 WHSC1L1 BHMT AS3MT EDF1 DNMT1 GAMT CARM1 NSD1 FBXO11 NNMT | |
| PROTEIN_COMPLEX_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_COMPLEX_BINDING INSL3 PEX6 MLH1 EDIL3 MUTYH PEX1 ADAM2 TGFBI PMS2 SHC1 SYK ADAM9 ADAM11 ICAM4 ACTN4 EGFL6 ICAM2 ICAM3 ACTN1 ACTN2 ACTN3 IRS1 THY1 AMBP ADAMTS8 RPAIN PEX26 DST ADAMTS5 CAV3 ADAMTS13 FCER2 ERCC8 DOCK2 ERCC6 SORBS1 INS ANGPTL3 PIK3R1 MSH6 COL4A3 TNXB MSH2 ADAM23 DMP1 TREX1 ATR COL16A1 ECM2 TRADD VWF ERBB2IP FBLN5 PCNA | |
| MONOSACCHARIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MONOSACCHARIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC2A8 SLC5A2 SLC2A5 SLC2A4 PPBP SLC2A3 SLC2A2 SLC5A1 SLC2A1 SLC37A4 | |
| TELOMERIC_DNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/TELOMERIC_DNA_BINDING SMG6 PIF1 HNRNPA2B1 TERF2IP TINF2 TERT TERF2 POT1 TERF1 PURA | |
| INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_BINDING YWHAG INSL4 YWHAH SOCS2 SOCS1 IGF1 SHC1 IGF2 IRS1 PIK3R1 | |
| PROTEIN_TYROSINE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_TYROSINE_KINASE_ACTIVITY NRP2 NRP1 EFNA3 TTK CLK1 DDR2 SKAP1 CAMKK2 TIE1 INSR EGFR TYRO3 TWF1 LYN EFNB3 ALK TYK2 DDR1 CRKL IGF2R PDGFRL ROR1 PDGFRA ROR2 PDGFRB TXK EFNA4 MST1R FRK FGFR1 FGFR4 ERBB4 ERBB3 ERBB2 PTK7 KIT CCL4 EPHB2 IGF1R EPHB6 MUSK PTK2B PTK6 TEK DYRK2 CRIM1 CSF1R NR4A3 ITK FLT1 LTK FLT3 RYK FLT4 MET TRIM27 AXL KDR EPHA5 NTRK1 DYRK1A TNK2 MERTK | |
| PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY PPP6C PPP2R3B CDC14B CYCS PPM1A TIMM50 PPM1B PTEN PPP1R3D MTMR3 PPM1G PPP1R3C PPM1D PPP1CA PPEF2 PPEF1 PPP2CB LCK CTDNEP1 PPM1M DUSP7 DUSP6 PPP5C PPP2R2A | |
| CARBON_OXYGEN_LYASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBON_OXYGEN_LYASE_ACTIVITY ALAD ECH1 CA14 CA5A EHHADH CA5B ECHS1 HADHA HADHB AUH ENO2 ENO3 PTS APEX1 NTHL1 ENO1 FH GMDS ACO1 CA12 CA11 CA9 CA8 CA7 CA6 CA4 CA3 CA2 OGG1 CA1 CBS | |
| ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY GALNT3 GALNT2 GALNT1 GALNT7 GALNT6 CSGALNACT1 GALNT5 GALNT4 B4GALNT2 GALNT8 EXTL2 B4GALNT1 | |
| SULFURIC_ESTER_HYDROLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SULFURIC_ESTER_HYDROLASE_ACTIVITY ARSB ARSD STS ARSE ARSF ARSG ARSH ARSI ARSJ ARSK GNS SULF2 IDS GALNS SULF1 ARSA | |
| TRANSCRIPTION_COACTIVATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSCRIPTION_COACTIVATOR_ACTIVITY MMS19 MYOD1 MED23 MED21 RFXAP AIP SMARCD2 SMARCD3 MED26 SMARCD1 MED27 PQBP1 RARA TBPL1 CIITA BCL10 POU2AF1 PCBD1 RXRB YY1 RXRA GABPA PPARGC1A PPARGC1B JUNB EP300 SMARCE1 MTF1 MED16 ABT1 TRIM32 MNT TFAP2B RIPK3 VGLL1 EDF1 TFAP2A TGFB1I1 KAT2A NFE2L3 SMARCA2 SMARCA4 TFAP4 CRTC1 NFKBIB MYEF2 NR2C2 ARNT ATF2 TCERG1 TFEC NPM1 TAF9 MAML3 NR1H4 RNF14 NR1H3 TFDP1 TAF4 UTF1 KLF7 NFE2 TRIP4 EPAS1 SUB1 MAML1 CREBBP MAML2 TAF7 SNW1 GTF2A1L PMF1 ATF6 NR1I3 NR1I2 PSMC3 DYRK1B GTF2F1 SMARCC1 SMARCC2 HTATIP2 COPS5 ELF3 PRRX1 ZEB1 NFKB2 MAX GTF2A1 HSF2 E4F1 MKL2 BRD8 NR2F1 SOX10 ZFX GMEB1 ESR2 HMGA1 NRIP1 PRPF6 JMY MED6 MED7 ZMIZ2 NCOA6 BRDT CARM1 SRCAP NFYC HCFC1 HCFC2 CALCOCO1 ECD NFATC4 TRIP11 APEX1 DTX1 TRIM24 YAF2 SP4 KAT2B RBM14 NR5A1 | |
| ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS http://www.broadinstitute.org/gsea/msigdb/cards/ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS FXYD2 ATP6V0E1 ATP1B1 ATP4A ATP1B3 ATP4B ABCB11 ATP1B2 ATP1A3 ATP1A4 ATP1A1 ATP1A2 ATP6V1B2 ATP7A ATP6V1C1 ATP2B1 ATP6V0C ATP2B3 ATP2B4 ATP2A2 ATP2C1 ATP2A3 ATP2A1 ATP7B | |
| ATP_DEPENDENT_RNA_HELICASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ATP_DEPENDENT_RNA_HELICASE_ACTIVITY DHX8 DHX9 UPF1 SKIV2L G3BP1 EIF4A3 DDX56 DDX18 DDX23 DHX38 DDX3X DDX25 DDX21 DDX20 DDX54 DDX43 DDX39A | |
| ACETYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ACETYLTRANSFERASE_ACTIVITY SAT1 HAT1 ACAT1 HADHA NAA16 AANAT KAT7 KAT8 GTF3C4 KAT6B KAT6A TAF1L ELP4 TAF1 TAF5 NAT1 NAT2 CREBBP BRCA2 EP300 NAA15 SMARCE1 NCOA3 EDF1 SRCAP | |
| CARBOHYDRATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBOHYDRATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC5A2 SLC5A1 SLC37A4 SLC35A1 SLC35A2 SLC35A3 SLC2A8 SLC35B1 SLC17A5 SLC2A5 PPBP SLC2A4 SLC2A3 SLC2A2 SLC2A1 SLC35B4 | |
| POTASSIUM_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/POTASSIUM_CHANNEL_ACTIVITY KCNH1 KCNK17 KCNJ15 KCNC1 KCNC4 KCNC3 KCNJ10 KCNIP2 KCNJ12 KCNJ14 KCNK10 KCNQ5 KCNQ3 CCT8L2 KCNK7 KCNK6 KCNK5 KCNQ2 KCNQ1 KCNG2 KCND3 KCNH2 KCNH3 KCNH4 KCNMB3 KCNMB4 KCNA2 KCNA1 KCNA4 KCNA3 KCNA6 KCNA5 KCNJ3 KCNMB1 KCNMB2 KCNJ1 KCNS3 KCNS1 KCNE1 KCNE2 KCNB2 KCNK1 KCNK3 KCNK4 KCNJ5 KCNN4 KCNJ4 KCNJ6 KCNN3 KCNN2 | |
| CHEMOKINE_RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CHEMOKINE_RECEPTOR_BINDING CXCL1 CCL1 CCL3 CCL2 CXCL5 CXCL3 CXCL2 C5 CXCL9 CCL8 PF4 CXCL6 CX3CL1 CXCL11 CCL5 CCL4 CCL28 CXCL12 CCL27 CCL7 CCL26 CXCL10 CCL24 CCL25 CCL22 CCL23 CCL20 CCL21 CKLF IL8 CCL19 CCL16 CCL15 CCL18 CCL17 CCL11 CCL13 CXCL14 CXCL13 CXCL16 CCR2 XCL1 XCL2 | |
| MONOOXYGENASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MONOOXYGENASE_ACTIVITY CYP3A4 CYP2J2 CYP1B1 CYP11B1 CYP2C18 CYP11B2 TH PAH KMO MSMO1 NOS2 TYR NOS2P1 CYP39A1 FMO1 FMO2 NOS3 CYP19A1 NOS1 CYP46A1 CYP26A1 CYP4A11 CYP4F8 CYP7B1 CYP17A1 CYP27A1 DOHH CYP2A6 CYP4F3 CYP4F2 CYP8B1 | |
| RHODOPSIN_LIKE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RHODOPSIN_LIKE_RECEPTOR_ACTIVITY F2RL2 F2RL3 AGTR2 HTR1B HTR1A GALR1 GALR3 GALR2 HTR1D CRY1 HTR1F HTR1E OR2S2 GPR139 C5AR1 GPR135 HTR4 OR1D2 OR1D5 SSTR4 SSTR5 SSTR2 SSTR3 SSTR1 HTR7 PDGFRL HTR6 MC2R PDGFRB C3AR1 DRD1 DRD3 CYSLTR1 DRD2 DRD5 DRD4 TRHR BDKRB1 NPY6R BDKRB2 HCRTR2 ADRB3 CNR1 CNR2 ADRA2A GRPR ADRA2C ADRA2B OR2C1 AVPR1B AVPR1A TBXA2R ADRA1B FPR3 MTNR1B ADRA1A FPR2 GHSR ADRA1D GRK1 MTNR1A OPRM1 MCHR1 TAS2R1 CCKAR TACR3 TAS2R4 OPCML TACR2 TAS2R5 TACR1 TAS2R3 GNRHR TAS1R3 TAS1R1 TAS1R2 KISS1R NMUR1 NMUR2 PAX8 TAS2R9 TAS2R8 MC5R TAS2R7 XCR1 HTR5A PTGER1 PTGER2 PTGER3 CCKBR PTGER4 CMKLR1 NPBWR1 NPBWR2 FSHR TAS2R16 CHRM5 TAS2R13 ADRB2 TAS2R14 ADRB1 CHRM4 CHRM3 OR2H2 CHRM2 CHRM1 GPR17 TSHR PTAFR TAS2R10 AVPR2 OPRK1 FPR1 OXTR HRH1 HRH3 HRH2 MAS1 TAS2R43 GP1BA MC3R HTR3B BRS3 PTGFR CXCR2 OR3A1 MC4R HTR2B NMBR HPGD OPN4 HTR2A F2R OPRD1 | |
| KINASE_INHIBITOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/KINASE_INHIBITOR_ACTIVITY SFN MBIP AGTR2 CDKN2A CDKN2B HEXIM2 PPP1R1B HEXIM1 CDKN2C CDKN2D DNAJC3 RHOH SOCS3 TAOK3 SOCS1 PKIG PKIA CAMK2N1 SH3BP5 CDKN1C GMFB CDKN1A CDKN1B GMFG MAPK8IP1 | |
| TRANSCRIPTION_COREPRESSOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSCRIPTION_COREPRESSOR_ACTIVITY E2F1 ZNF85 ZBTB32 THRB TSG101 E2F6 CBX4 HIRA CTCF PAWR ZEB1 HSBP1 MXI1 RBFOX2 FEV KCNIP3 HOXC6 SAP30 PLRG1 CASP8AP2 CREG1 HSF4 E4F1 NFIL3 NR2F2 ALX1 BATF3 ZNF593 LDB1 YY1 RELB SF1 MECP2 NR0B2 CSDA MXD1 MSC MBD1 DDIT3 JUNB MXD4 NRIP1 PFDN5 ZNF136 NAB2 HIPK2 MNT TGIF1 ZFPM2 PIAS1 SIAH2 NSD1 TDP2 EID1 ZNF274 TFCP2L1 TRIB3 ELK3 SUFU MEIS2 NR1D1 DRAP1 TFEC PEX14 SKIL BCOR APEX1 NR1H4 ENO1 SSX1 ERF KLF12 HTT TRIM28 RYBP SAP18 C19orf2 TRIM22 PPP1R13L UBP1 TONSL ATF5 ATF3 PSMC3 YAF2 DR1 ARHGAP35 JAZF1 ID4 ID3 DDX54 NCOR1 NCOR2 CIR1 | |
| PEPTIDE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PEPTIDE_RECEPTOR_ACTIVITY F2RL2 OPRM1 F2RL3 MCHR1 CCKAR OPCML TACR3 TACR2 TACR1 AGTR2 KISS1R GALR1 NMUR1 NMUR2 GALR3 GALR2 MC5R XCR1 C5AR1 CCKBR CMKLR1 NPBWR1 NPBWR2 SSTR4 SSTR5 SSTR2 SSTR3 SSTR1 MC2R GPR17 AVPR2 C3AR1 OPRK1 FPR1 OXTR BDKRB1 BDKRB2 NPY6R HCRTR2 MAS1 GRPR GP1BA MC3R BRS3 CXCR2 AVPR1B AVPR1A MC4R FPR3 FPR2 NMBR F2R OPRD1 | |
| DEOXYRIBONUCLEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DEOXYRIBONUCLEASE_ACTIVITY EXO1 DFFA DFFB MRE11A TREX2 TREX1 APTX MBD4 DNASE1L2 DNASE1L3 RAD50 DNASE1L1 ISG20 DNASE2 ERCC5 NME1 MAP1S OGG1 APEX1 ERCC4 ERCC1 FEN1 | |
| PHOSPHOINOSITIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOINOSITIDE_BINDING SYT1 WDFY1 CYTH3 CCDC88A EPB41 GPAA1 PIGU EEA1 THY1 PIGK PICALM RAB35 ZFYVE16 ADAP2 SCIN ARAP2 ARAP1 ARAP3 CD24 ZFYVE1 | |
| HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_NOT_PEPTIDEBONDSIN_CYCLIC_AMIDINES http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_NOT_PEPTIDEBONDSIN_CYCLIC_AMIDINES APOBEC2 DCTD GDA APOBEC1 ADARB2 APOBEC3G APOBEC3F AMPD3 ADA GCH1 AMPD1 MTHFD1 ADAT1 MTHFD2 ATIC CDA | |
| ATPASE_ACTIVITY_COUPLED http://www.broadinstitute.org/gsea/msigdb/cards/ATPASE_ACTIVITY_COUPLED ABCF1 XRCC5 ATP6V0E1 ATP1B1 ATP1B3 ATP1B2 SNRNP200 XRCC6 PEX6 TAPBP ATP2B1 DDX17 ATP2B3 ATP2B4 DDX18 DDX23 PEX1 DHX38 DDX25 VPS4B ATP8B1 DDX21 DDX20 TOP2A RBBP4 ATP4A MYO3A ABCB11 ATP4B RALBP1 G3BP1 MYH7 MYH6 MYH9 CLPX TTF2 RAD51 ATP6V1C1 RECQL EIF4A3 RFC3 BPTF ATP2C1 SMARCAL1 RUVBL2 SMARCA1 DDX39A ABCA8 MYL6 FXYD2 SKIV2L KATNB1 ATP6V1B2 ABCA3 ATP6V0C ERCC8 ERCC6 DDX3X KATNA1 CHD2 CHD1 ABCD3 ABCD4 CHD4 DDX43 CHD3 DHX8 DHX9 UPF1 MYO1E PIF1 ATP11B ATP1A3 ATP1A4 ATP1A1 ATP1A2 ABCB7 ABCG1 ABCG2 ATP7A DDX56 ATP2A2 ATP2A3 CCT8 ATP2A1 ABCC3 ABCC1 RAD54B ABCC2 DDX54 MYH10 ATP7B ABCC6 | |
| G_PROTEIN_COUPLED_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/G_PROTEIN_COUPLED_RECEPTOR_ACTIVITY F2RL2 GPR128 F2RL3 GPR126 GPR125 GPR124 GPR123 TMEM11 VIPR1 VIPR2 GHRHR SCTR LPHN2 LPHN3 AGTR2 HTR1B HTR1A GALR1 GALR3 GALR2 ELTD1 GLP2R HTR1D CRY1 HTR1F LPHN1 HTR1E OR2S2 GPR139 C5AR1 GPR133 GPR135 HTR4 OR1D2 OR1D5 SSTR4 CRHR1 CRHR2 SSTR5 SSTR2 SSTR3 SSTR1 HTR7 GPR56 PDGFRL HTR6 MC2R PDGFRB C3AR1 DRD1 GPR144 CYSLTR1 DRD3 DRD2 DRD5 DRD4 TRHR BDKRB1 NPY6R BDKRB2 GPR143 HCRTR2 ADRB3 CNR1 BAI1 CNR2 BAI2 GRPR ADRA2A BAI3 ADRA2C ADRA2B OR2C1 PTH2R CELSR3 EMR1 NPY AVPR1B MTNR1B TBXA2R FPR3 ADRA1B AVPR1A EMR4P ADRA1A EMR3 EMR2 FPR2 GHSR ADRA1D MTNR1A GRK1 OPRM1 CCKAR TAS2R1 MCHR1 TACR3 TAS2R4 OPCML TAS2R5 TACR2 TACR1 TAS2R3 GABBR1 GNRHR TAS1R3 GABBR2 TAS1R1 TAS1R2 CD97 KISS1R NMUR1 NMUR2 PAX8 PTH1R TAS2R9 TAS2R8 MC5R TAS2R7 CALCRL XCR1 HTR5A PTGER1 PTGER2 TPRA1 PTGER3 PTGER4 CCKBR CMKLR1 NPBWR1 NPBWR2 GRM1 FSHR GRM5 TAS2R16 GRM4 GRM3 CHRM5 ADRB2 TAS2R13 TAS2R14 CHRM4 ADRB1 GRM2 CHRM3 OR2H2 CHRM2 XPR1 GRM8 GRM7 CHRM1 GRM6 GPR17 TSHR PTAFR TAS2R10 TAPT1 AVPR2 OPRK1 GPR64 LANCL1 FPR1 OXTR GCGR HRH1 HRH3 HRH2 MAS1 TAS2R43 GP1BA MC3R HTR3B BRS3 PTGFR CXCR2 GPR110 OR3A1 GPR113 MC4R GPR114 GPR111 GPR112 HTR2B NMBR HPGD GPR115 HTR2A OPN4 GPR116 F2R OPRD1 | |
| TRANSCRIPTION_ACTIVATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSCRIPTION_ACTIVATOR_ACTIVITY MMS19 MYOD1 FOXO1 MED24 MED23 FOXO3 MED21 RFXAP TGFB1 AIP EPC1 SMARCD2 SMARCD3 MED26 MED27 SMARCD1 PQBP1 CEP290 RARA TBPL1 KAT6B CIITA BCL10 POU2AF1 RREB1 RXRB PCBD1 RXRA YY1 GABPA KDM5A ARID1A PPARGC1A PPARGC1B JUNB EP300 MTF1 SMARCE1 ABT1 MED16 TRIM32 MNT VGLL1 TFAP2B RIPK3 TFAP2A EDF1 TGFB1I1 KAT2A NFE2L3 SMARCA2 SMARCA4 TFAP4 NFKBIB CRTC1 UBE2V1 MYEF2 NR2C2 CXXC1 ARNT ATF2 FOXH1 TCERG1 TFEC NPM1 NKX2-1 TAF9 MAML3 RUNX1 RUNX2 RNF14 NR1H4 TFDP1 ZNF423 NR1H3 KLF6 UTF1 TAF4 KLF7 NFE2 TRIP4 EPAS1 SUB1 TAF8 PHB MAML1 CREBBP TAF7 MAML2 ESRRG BRCA2 GTF2A1L SMAD2 SNW1 PMF1 ATF6 ATF4 NR1I3 NR1I2 PSMC3 SMARCC1 DYRK1B GTF2F1 SMARCC2 HIVEP3 RSF1 ELF2 HTATIP2 ELF3 COPS5 ELF4 MITF PRRX1 TP63 NFKB2 ZEB1 GLI2 GLI1 MAX FUBP3 GTF2A1 ZNF148 HSF2 PAX8 E4F1 MKL2 NR2F1 BRD8 TAF1L SOX10 ZFX GMEB1 ESR2 HMGA1 PRPF6 JMY NRIP1 MED6 MED7 MED4 ZMIZ2 NCOA6 BRDT CAND2 FOXC2 CARM1 SRCAP GLIS2 NFYC HCFC1 CDH1 HCFC2 CALCOCO1 ECD NFATC4 NFATC2 TRIP11 APEX1 ERCC2 NFATC1 DTX1 ILF3 TRIM24 PSMG4 YWHAH MED30 SP1 YAF2 SP4 KAT2B IRF4 RBM14 NR5A1 | |
| COFACTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/COFACTOR_BINDING NOX4 ME1 HACL1 ALDH6A1 ME3 GCLC AIFM2 PPOX BIRC5 GRHPR AGXT MTRR NDOR1 ACOT7 NNT ALB ABAT SPR BDH2 HPGD WWOX AOC3 | |
| TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING ABCF1 TUFM EIF2C1 COPS5 EIF5A EIF2A PAIP2B EIF3C PET112 EIF3D EIF3B EIF3E EIF3F EEF2K DAZL EIF3J PABPC1 EIF2B2 EIF2B3 EIF2B4 EIF2B5 DAZ1 PAIP1 EIF2S3 GTF2H3 EIF2B1 GTF2H2 BOLL EIF4G1 EIF4B EIF4G2 EIF4E GSPT1 EIF4H MTRF1 EIF4A2 EIF2S1 GSPT2 EIF2S2 | |
| NEUROPEPTIDE_HORMONE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NEUROPEPTIDE_HORMONE_ACTIVITY VIP GRP CALCB UCN PNOC PENK NPY CRH QRFP CORT AGRP ADCYAP1 | |
| ENDORIBONUCLEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ENDORIBONUCLEASE_ACTIVITY RPP38 EXO1 RNASE1 DICER1 RNASE8 POP1 DBR1 RPP30 POP4 APEX1 RPP40 FEN1 POP7 | |
| VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY KCNH1 KCNJ15 KCNC1 KCNC4 KCNC3 KCNJ10 KCNJ12 HVCN1 KCNIP2 KCNJ14 KCNQ5 KCNQ3 KCNK6 SCN7A KCNQ2 KCNQ1 KCNG2 KCND3 SCN2B SCN2A CACNG5 CACNG4 CACNG2 CACNG1 SCN11A KCNH2 KCNH3 KCNH4 SCN1B KCNA2 KCNA1 CACNB1 KCNA4 CACNB2 KCNA3 CACNB3 KCNA6 KCNA5 CACNB4 KCNJ3 KCNJ1 KCNS3 KCNS1 PKD2 KCNE1 SCN9A KCNE2 SCN5A CACNA2D1 KCNB2 NOX1 KCNK1 CACNA1S KCNJ5 KCNJ4 KCNJ6 CACNA1G SCN4B CACNA1H CACNA1E CACNA1F CACNA1C CACNA1D CACNA1A SCN4A CACNA1B | |
| DNA_POLYMERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DNA_POLYMERASE_ACTIVITY PTGES3 POLI POLH POLG POLE POLA1 POLB POLD4 POLE4 DKC1 POLE2 POLE3 POLD1 TEP1 POLG2 POLQ TERT REV3L | |
| ACTIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ACTIN_BINDING MTSS1 LIMA1 PDLIM5 WASF2 CAPZA1 IQGAP2 VCL ANG CXCR4 PLS1 ABRA PARVG EGFR DBNL TWF2 CCDC88A MYO6 ACTN4 NCALD NEXN MYH9 FLNA ARPC1A TNNT2 UXT SMTN CCR5 CGN SCIN FLII DST LRPPRC ADD2 ADD1 SPTB GC ABLIM1 SHROOM1 SHROOM2 SHROOM3 SSH1 CALD1 SSH2 MYO9B ARPC4 ANLN FXYD5 CAPZB ESPN EZR MEFV SORBS1 DMD CNN2 WIPF1 SYNPO IPP GABARAPL2 SPTBN4 COTL1 TNNI3 LSP1 SYNE1 NRAP MAP1S SVIL HPCA MYO16 SPTBN2 SPTBN1 CYFIP1 MARCKS KPTN SPTA1 SPTAN1 MYH10 | |
| ION_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ION_BINDING S100A4 GDA S100A8 S100A7 LTBP4 S100A9 TPD52 DNASE1L2 DNASE1L3 MAP3K6 MAP3K5 DSPP ERAP2 MAP2K7 CDH24 S100A1 CDHR5 CIZ1 YY1 PIM1 PCLO MARK1 MARK2 LETM1 PITPNM3 PRDM4 NME1 PIAS2 NEK6 CDK5R1 FDX1 DUSP12 CALR MYT2 CALU ARIH2 RPS27 RPS29 CDA GPD2 CRIP1 KLF7 HPCAL1 CRIP2 HPCAL4 NIM1 SPHK1 OXSR1 CSRP1 S100A13 S100A12 CBLC CDC42BPG CBLB RNF7 RNF4 RNF5 TRPS1 NOTCH4 ATP2A1 CDC42BPA CDC42BPB NUAK2 ZEB1 KCNIP2 GLI2 CANX LATS1 CAMKK2 KCNIP3 LNPEP MTHFD2 TYR MMP20 ZNF146 SIK3 TCHH SRPK2 ACO2 TP53 MMP17 MMP16 MMP15 MMP14 MMP13 MMP12 GPR98 SRPK1 LRPAP1 MMP10 CHMP1A MAST1 MAST2 SIK2 NCS1 BNIP2 SIAH1 CAPS REPS2 POLR2K POLR2I EEA1 CETN1 HPRT1 SNRK PPP3CB PKD2 LIMD1 PEX12 CERK THBS3 THBS4 PLEK NLK MEX3B CAPN9 TRIM27 BIRC5 SOD1 MT1X MSRB2 ZNF22 MSRB3 RLF MNAT1 LRP1 MAPK12 FBLN2 RASSF1 CALM3 SIK1 APOBEC1 STK38 ZAK ATOX1 MMP9 MMP8 ADH1B APOBEC3G RCVRN CALB1 MMP2 APOBEC3F MMP1 APOA4 NLRC4 ZNF185 TIMM9 TPT1 RGN PRKACB ASPH LOX CIB1 FECH CA12 SCUBE1 HDAC10 STIM1 STK4 STK3 TIMM8B ISCU THBD SLU7 MYNN ME1 GCLC MYL2 STK11 PEF1 IRAK3 ECE2 RNF11 ADAM30 DYRK3 DYRK2 STK38L TESC S100P RABIF PIF1 CPNE6 DMP1 BRCA1 ATP7A SLC25A12 SLC25A13 S100B FLG S100G ABL1 PHEX ABL2 PDCD6 ATP7B SEPX1 FIGNL1 FOXK2 DUOX2 MAN1B1 PINK1 MOV10L1 CTCF MCTP2 ITIH1 GSN ANG KPNB1 MT3 MAN1A1 PDP1 MCTP1 SCIN NUCB2 ERN1 MDM2 ERN2 ZFPM2 PPM1M CA2 MDM4 PRNP AOC3 FKBP9 CABP2 CABP5 SPOCK2 ADAMTS13 CABP1 TIMM10 BRSK2 CABP4 BRSK1 TIMM13 DCT SPRR2C CALML3 PRSS2 COMP RASGRP1 FCN2 FCN1 PRSS3 TGM3 CD4 CCS CALML5 CHD4 HRC MSH6 MSH2 FBN1 ANXA1 MTL5 SIRT6 SPARC MAN1C1 SIRT2 ICK HSP90B1 TSSK1A ANXA10 MEP1B TSSK2 LTA4H TSSK4 TSSK3 RCN1 TSSK6 GCA CSN2 RCN2 | |
| 3_5_EXONUCLEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/3_5_EXONUCLEASE_ACTIVITY EXOSC7 MRE11A EXOSC2 TREX2 TREX1 RAD9A WRN RAD50 ISG20 RAD1 REXO2 APEX1 ERI1 | |
| TRANSCRIPTION_REPRESSOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSCRIPTION_REPRESSOR_ACTIVITY THRB HIRA CBX4 REST HDAC7 RBFOX2 MXI1 HOXC6 EPC1 CASP8AP2 ZNF396 PATZ1 TWIST2 KAT6B ZNF593 KDM5B YY1 RELB HDAC10 MECP2 NR0B2 CSDA FOXN3 DDIT3 JUNB MNT TGIF1 PIAS1 EID1 TFCP2L1 ELK3 MEIS2 HEXIM2 HEXIM1 DRAP1 TFEC DNMT3L SKIL BCOR NKX2-5 NR1H4 ZNF423 SSX1 DMBX1 NKRF IKZF4 BMP2 KLF12 CREBZF HTT PHB RYBP SAP18 C19orf2 FOXP3 UBP1 HDAC5 ATF5 HDAC4 TONSL NR1I2 ATF3 PSMC3 JAZF1 RFX3 DDX54 HDAC9 NCOR1 NCOR2 KLF4 HDAC6 ZNF85 E2F1 ZBTB32 PPARD RSF1 ARID4A ELF3 TSG101 E2F6 TP63 CTCF PAWR ZEB1 HSBP1 FEV KCNIP3 SAP30 ZNF350 PLRG1 CREG1 E4F1 HSF4 NFIL3 NR2F2 ALX1 BATF3 KHDRBS1 ZNF282 ARID5B LDB1 ARID5A SF1 RING1 IFI16 MXD1 MSC MBD1 NRIP1 MXD4 ZNF136 PFDN5 NAB2 HIPK2 ZFPM2 SIAH2 NSD1 TDP2 ZNF274 BCLAF1 PML TRIB3 ZBTB16 SUFU NR1D1 GATAD2A PEX14 BCL6 APEX1 KDM4A ENO1 ERF ZBTB7A TBX3 TBX2 TRIM28 ZNF24 ILF3 PHF12 TRIM22 PPP1R13L ATXN1 ID2 YAF2 ID1 PHB2 DR1 RBAK ARHGAP35 ID4 ID3 CIR1 | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_ALKYL_OR_ARYLOTHER_THAN_METHYLGROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_ALKYL_OR_ARYLOTHER_THAN_METHYLGROUPS SRM LTC4S GSTM5 PDSS1 PDSS2 RABGGTA GSTM1 FNTB GSTM2 GSTM3 FNTA GSTM4 AGPS MAT1A GGPS1 CHM GSTZ1 PGGT1B GSTA2 GSTA3 GSTA4 MAT2A HMBS GSTT1 GSTT2 MGST3 SMS MGST1 TRIT1 MGST2 | |
| COLLAGEN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/COLLAGEN_BINDING ACHE MMP9 LUM ITGA1 ITGA11 ITGA2 ITGA10 SPARC NID2 MAGI2-IT1 VWF DSPP GP6 USH2A | |
| SEQUENCE_SPECIFIC_DNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SEQUENCE_SPECIFIC_DNA_BINDING HNRNPAB NR6A1 FOXK2 FOXO1 RORB FOXO3 MLH3 TERF2IP GLI2 KIF2C ORC4 FOXF1 FOXF2 TERT ZW10 HNRNPA2B1 LEF1 MBD4 MBD2 NR0B1 HMGA2 HMGA1 PURA BPTF TFAP2B FOXC2 ORC5 FOXC1 FIGLA ELK3 POT1 CXXC1 FOXH1 ORC2 BCL6 TINF2 FOXD1 FOXD4 TERF2 TERF1 DMBX1 SREBF1 FOXL1 SMG6 TBX3 TBX2 CEBPG TBX5 PIF1 TRIM28 SMAD4 SMAD3 TBX1 FOXP3 GCM2 ORC3 SP1 NR5A2 | |
| CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY PDE3B PDE3A CNP PDE4D PDE10A PDE4C PDE7B PDE1B PDE2A PDE1C PDE7A PDE4A PDE4B PDE1A | |
| NUCLEAR_HORMONE_RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/NUCLEAR_HORMONE_RECEPTOR_BINDING MMS19 MED24 DAXX SMARCD3 TRIP12 MED12 MED14 MED13 HMGA1 PPARGC1B NRIP1 PRPF6 TACC2 MED4 OASL MED30 YWHAH NUP62 MED16 MED17 NCOA6 THRAP3 JMJD1C TGFB1I1 DDX54 NSD1 ZNHIT3 MED1 | |
| KINASE_ACTIVATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/KINASE_ACTIVATOR_ACTIVITY ALS2 BCL10 CDK5R1 MADD MAPK8IP2 MOB1B GHRL MALT1 FGF13 AFAP1L2 CD24 IL2 | |
| PROTEIN_DEACETYLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_DEACETYLASE_ACTIVITY HDAC5 HDAC3 HDAC2 HDAC1 HDAC10 HDAC11 HDAC7 HDAC8 SIRT2 HDAC6 | |
| GUANYL_NUCLEOTIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/GUANYL_NUCLEOTIDE_BINDING SEPHS1 HBS1L RRAGA ARF6 RRAGB RRAGC CLP1 NMUR2 RALB RALA RHOB TGM3 SCG5 RAB26 MX1 EIF2B2 GNL1 RHOH GNL3 RAP2B GTPBP1 EEF1A1 GTPBP4 GTPBP6 NCF1 RAN ARHGEF5 ARFIP2 TPX2 DRG2 GEM TRIM23 ARL3 RERG RND3 NME1 ARF3 RAB22A RHEB RIT1 ARL8A RIT2 ARL8B SEPT6 SEPT7 GBP2 GBP1 | |
| DEAMINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DEAMINASE_ACTIVITY APOBEC2 DCTD GDA APOBEC1 GNPDA1 ADARB2 APOBEC3G APOBEC3F AMPD3 ADA AMPD1 ADAT1 CDA CRYM | |
| DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY POLI POLH POLG POLE POLA1 POLB POLD4 POLE4 POLE2 POLE3 POLD1 POLG2 POLQ REV3L | |
| ENZYME_INHIBITOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ENZYME_INHIBITOR_ACTIVITY SNCB TNFSF14 IQGAP2 MBIP IQGAP1 APP AGTR2 APOA2 LPA CDKN2A CDKN2B CDKN2C PPP1R1B PPP1R1A CDKN2D DNAJC3 TWIST1 RECK SOCS3 PKIG SOCS1 CST3 CST2 CST1 SERPING1 PKIA SAG CST8 RENBP CST6 SERPINF1 CST7 ARRB1 TNFAIP8 CST5 ATPIF1 PPME1 SERPINA10 CDC42SE1 TIMP2 SERPINH1 TIMP1 OAZ2 OAZ3 GCKR OAZ1 HEXIM2 HEXIM1 LMTK2 ANGPTL3 SPP2 ANGPTL4 TESC TAOK3 PRPSAP1 SERPINI1 PDE6H PDE6G CAMK2N1 SERPINI2 PRPSAP2 HSPBP1 CDKN1C LCN1 CDKN1A CDKN1B PI3 TNK2 PDZD3 SPINK5 GPX1 TRIAP1 SERPINA7 SERPINA6 SPINT2 SERPINA5 IPO5 SERPINA4 SERPINA2 RHOH ARL2 ABCE1 ANP32E SPINT1 AMBP SERPINB9 SERPINB6 SERPINB8 SERPINB7 SERPINB3 PROS1 CABP1 RNH1 RTKN SFN STUB1 SET AGT SERPINB10 PTN SCG5 SERPINB12 THBS1 CD27 GPS1 BIRC5 XIAP ANXA5 GPS2 ANXA2 SH3BP5 GMFB PPP1R2 PPP1R8 GMFG PDC FAF1 MAPK8IP1 CSN2 | |
| TUBULIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/TUBULIN_BINDING RABGAP1 VAPB HOOK3 TUBGCP3 NDE1 TUBGCP6 TUBGCP5 RAE1 KATNA1 TARDBP MAPT CEP290 CLASP1 CLASP2 CDK5RAP2 DCX APC DYNC1I1 GABARAPL2 GABARAPL1 ARHGEF2 CCDC88A KIF5B NCALD HTT BRCA2 BIRC5 POLB RACGAP1 MARK4 CENPJ SUN2 GABARAP RAB11FIP5 UXT ATG4D ATG4C MAP1S TPPP ATG4A CLIP1 ARL8A MAPRE1 ARL8B STMN1 PRNP LRPPRC | |
| PRIMARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PRIMARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ABCA8 ABCF1 FXYD2 ATP6V0E1 ATP1B1 ATP1B3 ATP1B2 ATP6V1B2 ABCA3 TAPBP ATP2B1 ATP6V0C ATP2B3 ATP2B4 ATP8B1 ABCD3 ABCD4 ATP4A ATP4B ABCB11 ATP11B ATP1A3 ATP1A4 ATP1A1 ATP1A2 ABCB7 ABCG1 ABCG2 ATP7A ATP6V1C1 SEC61B ATP2A2 ATP2C1 ATP2A3 ATP2A1 ABCC3 ABCC1 ABCC2 ATP7B ABCC6 | |
| PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY F2RL2 C3AR1 CASR ENPP7 PDIA3 ENPP2 ENPP3 PDE3B CNP BDKRB2 EDNRA PDE1B PDE1C PDE4A PLCH1 PDE4B PDE1A PLCD1 APEX1 PLCB2 PLD3 GDE1 PLD2 PLD1 CCKBR PDE4D PDE10A PDE3A PDE4C PDE7B CHRM5 PLCE1 PDE2A CCR5 CHRM3 PDE7A CHRM1 SMPD1 SMPD4 SMPD2 | |
| RNA_DEPENDENT_ATPASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RNA_DEPENDENT_ATPASE_ACTIVITY DHX8 DHX9 UPF1 SKIV2L G3BP1 EIF4A3 DDX17 DDX56 DDX18 DHX38 DDX3X DDX23 DDX25 DDX21 DDX20 DDX54 DDX43 DDX39A | |
| INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHATASE_ACTIVITY MTMR2 INPP1 MTMR14 IMPA2 IMPA1 SYNJ1 INPP4B INPP5E INPP5D OCRL PTEN INPP5K | |
| NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC29A1 SLC23A1 SLC29A2 SLC25A4 AQP9 SLC25A5 SLC35B2 SLC23A2 SLC25A19 SLC28A2 | |
| LIPID_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/LIPID_KINASE_ACTIVITY PIKFYVE PIK3CG PIK3CB PIK3C2A SPHK1 PIK3C3 PIK3CA CERK PIK3R3 ATM PIK3R2 PIP4K2B | |
| ENDOPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ENDOPEPTIDASE_ACTIVITY MASP1 MASP2 THOP1 LGMN MMP9 MMP8 IDE RCE1 MMP3 MMP2 HTRA2 HTRA1 FAP CFI CFD F11 F12 CAPNS1 F10 USP1 F9 F7 F2 ADAMTS2 ACR CTSL2 CELA3A KEL CTSL1 ECE2 KLKB1 CELA2B FURIN TINAG APEH ASPRV1 SOLH SPG7 CORIN PDIA3 UCHL1 MMP28 MMP24 MMP20 CASP3 CASP9 TPP2 CASP8 LTF USP11 CASP1 USP16 PRSS36 USP15 USP14 USP13 GZMA MMP17 MMP16 GZMB CTSS MMP15 MMP14 MMP13 MMP12 PROC MMP11 BLMH CTSK SENP1 ATG4D ATG4C CAPN11 PSEN1 CTSO CTSE CTSD CTSB PMPCA CTSH CTSG USP7 USP6 PREP USP8 USP2 USP5 USP9X USP4 PRSS1 C1R C1S PCSK2 REN PRSS2 PRSS3 PITRM1 TOR1A PCSK9 PGA4 PCSK6 HGFAC CAPN6 KLK8 MBTPS2 CAPN5 KLK2 CAPN9 KLK1 TMPRSS6 CAPN3 PLG CASP10 MMP23B CASP14 MEP1A ELANE | |
| MAGNESIUM_ION_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/MAGNESIUM_ION_BINDING SIK1 ZAK STK38 NUAK2 FIGNL1 FOXK2 PINK1 MOV10L1 LATS1 MAP3K6 MTHFD2 MAP3K5 NLRC4 SIK3 PRKACB MAP2K7 SRPK2 STK4 SRPK1 STK3 MARK1 MARK2 MAST1 SIK2 MAST2 NME1 ERN1 ERN2 NEK6 GCLC STK11 BRSK2 BRSK1 HPRT1 IRAK3 SNRK TGM3 DYRK3 CERK DYRK2 STK38L MSH6 TESC S100P MSH2 NLK PIF1 SPHK1 NIM1 OXSR1 ICK CDC42BPG MAPK12 TSSK1A CDC42BPA TSSK2 TSSK4 ABL1 TSSK3 ABL2 TSSK6 CDC42BPB | |
| STRUCTURAL_MOLECULE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/STRUCTURAL_MOLECULE_ACTIVITY RPL18 MRPL41 RPL19 RPL14 RPL13 CROCC RPL15 RPLP2 PLEC CD2AP DSPP RPLP0 RPLP1 PLS1 FAU RPL11 INA OPTC MATN3 MRPL52 MRPL51 STRN4 MATN1 MYH7 MYH6 DCTN3 PRELP KRT19 RPS18 PGM5 RPS19 RPS16 KRT17 ACTL7A RPS17 ACTL7B LAMC3 SPAG4 KRT15 RPS14 RPS15 KRT14 RPS12 RPS13 RPS10 LAMC1 RPS11 ADD3 LMNB1 TUBB7P RPS25 RPS26 RPS27 RPS28 RPS29 IMPG1 DMD KAL1 IMPG2 MRPL55 AGRN RPS20 RPS21 LAMB1 RPS23 HIP1 RPS24 CHI3L1 KRT31 RPS9 RPS6 RPS5 RPS8 RPS7 LAMA2 KRT38 BFAR LAMA1 LAMA4 KRT37 RPL18A MAP4 MAP7 GFAP MYBPC2 MYBPC1 MYBPC3 VILL MAPT ACTA1 RPL41 RPL3L SPRR3 RPS4Y1 RPL27A RPL35 RPL37 RPL38 EPB41L4B RPL39 MRPL10 NUMA1 SORBS3 RPL30 MRPL12 MYOM2 RPL31 SORBS2 RPL34 ACTL6B MYOM1 ACTC1 RPL26 RPL27 RPL24 RPL28 RPL29 CYLC2 MRPL23 FBLN1 RPL22 FBLN2 RPL21 SEPT5 LOR SEPT4 MPZL1 TTN KLHL3 ANK1 ASPH TUBG1 TUBG2 KRT85 TFPI2 LAD1 MGP ACTN2 ACTN3 MEPE BICD1 NEBL CCDC6 ARPC1B DSP CSTA MFAP5 DST SEPT7 MYL6 CAV1 MYL5 MRPS14 MYL2 MYL3 MRPS12 ARPC4 ARPC5 LLGL1 MYL9 RPL7 ARPC3 ARPC2 RPL6 RPL9 PPL RPL8 RPL3 TUBE1 RPL5 RPL4 RPL7A IVL MUC2 EPB41 MRPS22 EPB42 EFEMP2 MRPS24 SPTBN4 BFSP1 BFSP2 MYLPF RPL23A CORO1A CDC42SE2 SPTBN2 MYH11 SPTBN1 SPTA1 RPS2 RPS3 DES RPS3A MSN MRPS7 RPS4X EVPL SMTN MATR3 KRT6B TCAP VIM RPS15A SPRR2G SPRR2F SPRR2E TPM2 TPM1 TPM4 MYOT KRT9 KRT5 SPRR2C MYL6B SPRR2D SPRR2A COMP MYBPH SPRR2B KRT1 ACAN KRT2 KRT3 ODF2 FBN2 NEFL MYOC NEFM ACTB COL4A4 COL4A2 PLP1 FBN1 ANXA1 MAL KRT75 TMEM48 NEB RPL13A SPRR1A SPRR1B MAPK8IP2 SPTAN1 | |
| SIALYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SIALYLTRANSFERASE_ACTIVITY ST3GAL1 ST6GALNAC6 ST6GAL1 ST3GAL3 ST6GAL2 ST3GAL2 ST3GAL5 ST3GAL4 ST3GAL6 ST8SIA2 | |
| DOUBLE_STRANDED_RNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/DOUBLE_STRANDED_RNA_BINDING ADARB2 DICER1 APTX TLR3 ILF3 MBNL1 ZNF346 TLR7 TLR8 STAU2 STAU1 TARBP2 OASL A1CF ILF2 LRRFIP1 EIF2AK2 | |
| IONOTROPIC_GLUTAMATE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/IONOTROPIC_GLUTAMATE_RECEPTOR_ACTIVITY GRIK1 GRIN2B GRIA2 GRIK2 GRIN2C GRIA1 GRIK3 GRIK4 GRIN2A GRIK5 | |
| ACETYLGLUCOSAMINYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ACETYLGLUCOSAMINYLTRANSFERASE_ACTIVITY MGAT4B MGAT4A GCNT4 GCNT3 GCNT2 EXTL2 B3GNT8 MGAT2 POMGNT1 LARGE B3GNT5 A4GNT OGT EXT1 GCNT1 PIGA | |
| RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/RECEPTOR_BINDING SYT1 CGA EDN3 UTS2 CGB CADM1 EFNA1 PGF EFNA2 BTC TUBB4B EDN1 GDF5 STOML2 MED24 EDIL3 APP BDNF MYD88 ADAM2 APOF IFNG ERAP1 GDF9 IFNK QRFP FIZ1 PRLH ADAM9 SYK CRTAM YARS STC2 EFNB3 EFNB1 EFNB2 MED12 MED14 MED13 PPARGC1B THY1 PITPNM3 ADAMTS8 MED16 CD40LG MED17 VEGFA CCR2 F2 STC1 EFNA5 TGFBRAP1 TGFB1I1 CHGB ADAMTS5 ZNHIT3 GLG1 SIVA1 RTP2 ERBB2 RTP1 FCER2 GAST POMC CD72 ADCYAP1 IL17C ALCAM IFNA2 IL17A IL17B IFNA7 INS IFNA5 CKLF IL17F IFNA4 IFNA8 AGRP BMP4 NTF4 IL1RN MSTN COL16A1 ECM2 GAS6 APOL2 GH2 GH1 OASL PENK NUP62 NPY PYY AREG ASIP NCOR2 FGF6 FGF7 FGF9 DAXX TNFRSF11B IL4 SAA1 TGFA SPG21 ANGPT1 FGF1 ANGPT2 FGF3 LAG3 FGF4 JAKMIP1 ADAM11 GIP ICAM4 EGFL6 ICAM2 ICAM3 CD160 SLIT2 LRPAP1 INHBB PROK2 INHBA MED4 IL18BP EREG NCK1 INHBC IL12A NPPB IL12B SEMA4D NSD1 MED1 CSF3 BID CXCL1 CSF2 CXCL5 C3 CSF1 CXCL3 CXCL2 C5 CXCL9 LANCL1 NMB CXCL6 CCL28 NAMPT CCL27 MIF CCL26 CCL24 CCL25 CCL22 CCL23 SORBS1 CCL20 CCL21 SQSTM1 PCSK9 TRIP12 RASA1 NMU FYB IL3 IL5 IL8 IL7 CCL19 IGF1 IGF2 TRIM24 CCL16 CCL15 CLEC11A GABARAP CCL18 CCL17 CCL11 YWHAG CCL13 CNTF YWHAH DKK1 ERBB2IP GLA EPGN FBLN5 GFRA1 HBEGF IL36RN GFRA3 IL2 MMS19 BMP10 MTSS1 FGF18 FGF14 FGF17 IL19 ARNT2 F2RL1 FGF16 JAG2 FGF11 TGFB3 FGF10 FGF13 OSGIN1 CSPG5 FGF12 CXCL11 CXCL12 TGFB1 TAPBP CXCL10 TGFB2 APOA1 RLN1 CASP8AP2 SMARCD3 APOA5 TGFBI TDGF1 SPRED2 PDGFC SPRED1 IL29 ACTN4 SOCS2 PLXNB1 MADD NUDT6 IL27 SOCS1 PICK1 IL25 ACTN1 FADD ACTN2 DLL1 ACTN3 IL21 IRS1 IL20 TACC2 PTHLH DLL4 SDCBP EDA DST WNT5A SRI CCL1 PPY CCL3 PLXNC1 DERL1 CCL2 GRB2 DIAPH2 CYTL1 CCL8 GIPC1 CX3CL1 ENSA TRH CCL5 CCL4 CCL7 TUBB DOCK2 DNAJA1 ANGPTL1 AIMP1 ANGPTL3 EGF ANGPTL2 GABARAPL2 GABARAPL1 UCN TRIP4 GNRH1 ADAM23 GNRH2 DMP1 SNW1 REEP1 WIPI1 MUC4 PSMC5 CXCL14 CXCL13 CXCL16 GLMN DDX54 XCL1 CORT PCSK1N TRIP6 XCL2 SST INSL3 IFNA21 INSL4 PIDD CLCF1 ANG SHC1 MSN PRL NPFF KNG1 INHA SLC9A3R1 HMGA1 CDK5 NRIP1 PRPF6 OSM GRP AMH GHRH GRN LCK NCOA6 GHRL JMJD1C ICOSLG VIP MBL2 TNF ADAMTS13 CTF1 NDP AKAP9 PF4 TSHB ARPP19 TAC3 CALCA CALCB TYMP REN TMED1 PTH FIGF PIK3R1 SCG2 THPO COL4A3 SECTM1 TNXB DTX1 ANXA1 BZRAP1 DBI VWF HSP90B1 MED30 PNOC THRAP3 CRH BRE GDF10 JAK2 IFNA14 IFNA13 GDF15 IFNA16 CHRNA10 F2R IFNA17 | |
| SERINE_HYDROLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SERINE_HYDROLASE_ACTIVITY ACR PREP ACHE CELA3A MASP1 CORIN MASP2 PRSS1 C1R C1S PCSK2 HTRA2 HTRA1 TPP1 KLKB1 PRSS2 TPP2 TOR1A PRSS3 LTF PCSK9 CFI PRSS36 PCSK6 CFD HGFAC DPP4 F11 F12 KLK8 F10 CELA2B KLK2 GZMA F9 GZMB KLK1 F7 TMPRSS6 FURIN PLG PROC APEH F2 CPD CTSG | |
| NF_KAPPAB_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/NF_KAPPAB_BINDING BCL10 CDKN2A TP53BP2 PIAS3 RELA TAF4B GSK3B NPM1 NFKBIA FAF1 COMMD7 | |
| RECEPTOR_SIGNALING_PROTEIN_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RECEPTOR_SIGNALING_PROTEIN_ACTIVITY GNAZ ACVRL1 ZAK CSPG4 DAXX ACVR1C MAP3K7 ACVR1B MAP3K6 BAG4 MAP3K5 MAP3K4 BAG1 MAP3K9 IL4R SHC1 NSMAF FRS2 INSR IRAK2 TYRO3 IRAK1 SOCS2 LYN CD3E ALK CDK5 IRS1 NCR1 PPARGC1B TRAT1 ACVR2A MAPK1 PLCE1 ACVR2B IL18BP MAPK4 MAP3K10 MAPK9 MAPK8 MAPK7 MAP3K13 MAP3K11 ACVR1 IFITM1 ERBB2 MAP4K1 KIT SP110 CCL4 ARNT MAP3K3 FCGR1A SH2B2 SKIL DCLK1 BLNK TYROBP AMHR2 TBL3 SMAD7 IL1RL1 TGFBR1 SMAD6 NLK TGFBR2 IL1RN MAPK11 MAPK10 STAT1 STAT3 STAT2 IKBKE CDKN1B CD19 MAPK12 ARF1 MAPK13 MAPK14 MAPK15 IL36RN PIP4K2B | |
| CARBON_CARBON_LYASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBON_CARBON_LYASE_ACTIVITY BCKDHA ALDOA GGCX DDC ODC1 HACL1 MVD ALDOC BCKDHB ALDOB ACMSD PCK1 UMPS MLYCD HDC AMD1 UROD GAD1 | |
| LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS http://www.broadinstitute.org/gsea/msigdb/cards/LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS YARS NARS DARS FARS2 SARS GARS QARS VARS SARS2 KARS FARSB MARS2 FARSA MARS | |
| PROTEIN_BINDING_BRIDGING http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_BINDING_BRIDGING LOR RUSC1 FCRL2 ITSN2 SKAP2 SKAP1 SLA ARHGAP4 SHB ARHGAP6 ARHGAP1 GAB1 SH3BGR CNTNAP1 STAM KHDRBS1 IRS4 SOCS2 SLA2 RAD50 ST13 SH2D2A SH2D3C GRB10 EVPL CRKL SH2D3A DSP CSTA GRAP2 GRB14 SNX9 GRAP GRB2 FKBP4 ABI2 ARPC4 STUB1 SRC GATAD2A BCL3 SH2B2 IVL BLNK CNKSR1 VAV3 TP53BP2 ANXA1 SH3BGRL LAT EPS8 SPRR1A LASP1 SPRR1B CHN1 CHN2 GRB7 SH3BP2 TOB1 | |
| RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RECEPTOR_ACTIVITY KLRC2 KLRC3 IL9R OSMR MED24 LPHN2 PGR LPHN3 HTR1B AGTR2 CUL5 HTR1A GRIN2B GRIN2C INTS6 HTR1D KLRD1 ROS1 HTR1F HTR1E LPHN1 PTPRJ KLRB1 OR2S2 TYRO3 PTPRK PTPRM PTPRF RXRB PTPRG PTPRH RXRA PTPRR RXRG LIFR MED12 GRIN2A PTPRS MED14 PTPRT COLEC12 MED13 PTPRU PTPRN PTPRO HLA-DQA1 SSTR4 SSTR5 SSTR2 SSTR3 SSTR1 MED16 MED17 MC2R ROR1 ROR2 MST1R UNC13B KLRC1 TNFRSF6B IL1R1 ERBB4 ERBB3 HLA-DRB3 NPY6R HCRTR2 ADRB3 MUSK PVRL1 PROCR PVRL2 HLA-DRB4 HLA-DRB5 HLA-DPB1 KLRF1 HLA-DOA HLA-DOB GUCY2F RPSA PTH2R TGFBR1 TGFBR2 CD300C GUCY2D AVPR1B AVPR1A FPR3 FPR2 CHRNE P2RX6 OPRM1 MSR1 SLC20A1 LDLR SLC20A2 KISS1R NMUR1 NMUR2 IL4R MC5R GUCY1A3 HTR5A BRD8 IL13RA2 GHR AR ZP2 CMKLR1 NPBWR1 NPBWR2 IL6R LRPAP1 KLRG1 XPR1 GUCY1B3 NPY2R OPRK1 GPR64 FPR1 IL7R MAS1 MC3R HTR3B ATRN TRIM27 AXL STAB2 LRP1 P2RY11 STAB1 MC4R LRP6 GFRA1 LRP8 NMBR HTR2B HPGD GFRA2 HTR2A GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 PGLYRP1 NR2E1 MARCO PGLYRP4 GALR1 PGLYRP2 GALR3 PGRMC2 PGLYRP3 GALR2 IL15RA UNC5C INSR EGFR RET PTPRN2 HLA-E HLA-G HLA-F GABRR2 GABRR1 GPR56 RNF139 KIR3DL1 C3AR1 DRD1 DRD3 CYSLTR1 DRD2 DRD5 DRD4 PTK7 CNTFR ABCA1 NR2C1 IL12RB2 VDR IL12RB1 P2RY2 BTN1A1 TEK P2RY1 ADRA2A GRPR ADRA2C ADRA2B GABRQ GABRP MRC1 GABRD GABRE TLR10 CUBN TNFRSF13B MET NR4A3 P2RX5 P2RX7 P2RX1 CXCL16 ADRA1B TBXA2R MTNR1B ADRA1A MERTK ADRA1D MTNR1A CLDN4 CLDN3 GABBR1 GABBR2 CXADR SLC1A5 PAX8 CSF2RB TIE1 CSF2RA PTGER1 PTGER2 PTGER3 PTGER4 ESR2 M6PR TAS2R16 CHRM5 TAS2R13 ADRB2 TAS2R14 ADRB1 CHRM4 CHRM3 CHRM2 SIGLEC8 CHRM1 IGF2R SIGLEC7 MCC GPR17 TREM1 TREM2 TSHR PTAFR TAS2R10 ACVR1 TAPT1 CRLF1 FKBP3 NR3C2 OXTR NR3C1 SEC63 IGF1R HRH1 ANXA9 HRH3 HRH2 DNER TAS2R43 CD4 KLRAP1 CD7 AMHR2 EBP FLT1 FLT3 FLT4 FZD10 MED30 EPOR OPRD1 DMBT1 PVR GPR128 GPR126 GPR125 IL6ST GPR124 GPR123 EFNA3 OR1E2 TMEM11 LILRA1 LILRA2 LILRA3 CD46 CHRNA5 CLEC4A CHRNA4 CHRNA7 RARA CHRNA6 RARB CRY1 CHRNA1 CHRNA3 CHRNA2 CD3G RARG GPR139 C5AR1 EFNB3 GPR133 GPR135 HTR4 OR1D2 OR1D5 CRHR1 CCR8 LILRB2 CRHR2 CCR6 CCR5 LILRB5 TACSTD2 CD33 LILRB3 HTR7 HTR6 LILRB4 PDGFRL PDGFRA PDGFRB AMFR EFNA4 SIVA1 GPR144 TRHR MMD FCGRT BDKRB1 BDKRB2 GPR143 EPHB2 LGALS3BP EPHB6 CD69 BAI1 BAI2 BAI3 TRAM1 OR2C1 CELSR3 SLAMF1 AGER KDR EPHA5 NR1I3 NPY NTRK1 CHRNB4 CHRNB2 IL5RA LGTN CLEC7A CHRNB1 GHSR GRK1 NRP2 MCHR1 TAS2R1 CCKAR PPARD ACVRL1 NRP1 TAS2R4 IL27RA TAS2R5 TAS2R3 TAS1R3 ANPEP TAS1R1 TAS1R2 ASGR1 SEC62 ASGR2 TNFRSF11B TNFRSF11A NR2F6 TAS2R9 TAS2R8 TAS2R7 XCR1 ICAM1 TPRA1 CCKBR LY96 CD160 NFAM1 GRM1 GRM5 CLEC1A TNFRSF10A GRM4 MED4 TNFRSF10C GRM3 GRM2 OR2H2 GRM8 TNFRSF10D GRM7 GRM6 GPA33 TOMM22 SEMA4D MED1 CLEC1B AVPR2 OPN1LW LANCL1 FKBP1A GCGR NR1D1 IL10RB IL10RA CLEC2D CD28 FZD9 LY75 FZD8 CYTH3 PTPRZ1 RRBP1 LRRN2 OPN1MW NPR2 FZD3 BRS3 NPR3 FZD2 PTGFR ITPR3 FZD5 FZD4 ITPR1 FZD7 ITPR2 FZD6 ABCC9 GRIA2 GRIA1 PTCH1 ABCC8 CD14 VLDLR OPN4 F2RL2 F2RL3 TSPO THRA THRB PLXNA1 GABRB3 GABRB2 GABRB1 F2RL1 TLR2 PRKCB VIPR1 VIPR2 GHRHR IL31RA SCTR GP6 ROBO1 ROBO4 CSF3R ELTD1 GLP2R SPN PLXNB1 TNFRSF17 TNFRSF14 APLNR AHR IGSF6 IGSF1 KIR2DL1 KIR2DL3 KIR2DL4 FGFR1 FGFR4 IL22RA1 ADCYAP1R1 KLRK1 ITGAX FOLR1 CNR1 CNR2 SCARB1 CSF1R GABRA2 GABRA1 GABRA4 RYK GABRA3 GABRA6 EMR1 EMR4P EMR3 SCARA3 EMR2 IL3RA IL22RA2 OPCML TACR3 TACR2 TACR1 SORL1 GNRHR BCAM DDR2 ACVR1C CD97 ACVR1B CXCR4 CXCR6 PTH1R CNTNAP1 CALCRL IFNGR2 IFNGR1 GABRG2 NRXN3 PRKCI PRKCH PRKCG NRXN1 ALK NCR2 PRKCE FSHR IFNAR1 PRKD1 SMO ACVR2A IFNAR2 DDR1 TNFRSF9 ACVR2B PRKD3 PRKCZ CD244 RTN4RL1 TNFRSF25 TNFRSF8 TNFRSF4 SCARF1 TNFRSF1A TNFRSF1B TNFRSF18 IL2RG GP1BA RTN4RL2 MR1 PLA2R1 CRIM1 TNPO3 PTPRB PTPRC PTPRD IL2RB PTPRE IL2RA LTK PTPRA EDA2R CXCR2 GPR110 OR3A1 OR3A2 THRAP3 GPR113 GPR114 GPR111 GPR112 GPR115 F2R GPR116 | |
| DEACETYLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DEACETYLASE_ACTIVITY HDAC5 AADAC HDAC3 HDAC2 HDAC1 HDAC10 HDAC11 HDAC7 HDAC8 SIRT2 HDAC6 | |
| TRANSMEMBRANE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSMEMBRANE_RECEPTOR_ACTIVITY KLRC2 KLRC3 IL9R OSMR LPHN2 LPHN3 AGTR2 HTR1B HTR1A GRIN2B GRIN2C INTS6 HTR1D KLRD1 HTR1F HTR1E LPHN1 KLRB1 PTPRJ TYRO3 OR2S2 PTPRK PTPRM PTPRF PTPRG PTPRH LIFR PTPRR GRIN2A PTPRS COLEC12 PTPRT PTPRU PTPRN PTPRO HLA-DQA1 SSTR4 SSTR5 SSTR2 SSTR3 SSTR1 MC2R ROR1 ROR2 MST1R KLRC1 IL1R1 ERBB4 ERBB3 HLA-DRB3 NPY6R HCRTR2 ADRB3 MUSK HLA-DRB4 HLA-DRB5 KLRF1 HLA-DPB1 HLA-DOA HLA-DOB RPSA PTH2R TGFBR1 TGFBR2 CD300C AVPR1B FPR3 AVPR1A FPR2 CHRNE P2RX6 OPRM1 MSR1 LDLR KISS1R NMUR1 NMUR2 IL4R MC5R HTR5A IL13RA2 GHR CMKLR1 NPBWR1 NPBWR2 IL6R LRPAP1 XPR1 OPRK1 GPR64 FPR1 IL7R MAS1 MC3R HTR3B TRIM27 AXL STAB2 STAB1 MC4R LRP6 GFRA1 LRP8 NMBR HTR2B HPGD GFRA2 HTR2A GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 GALR1 GALR3 GALR2 IL15RA UNC5C INSR EGFR PTPRN2 HLA-E HLA-G HLA-F GABRR2 GABRR1 GPR56 KIR3DL1 C3AR1 DRD1 DRD3 CYSLTR1 DRD2 DRD5 DRD4 PTK7 CNTFR IL12RB2 IL12RB1 TEK ADRA2A GRPR ADRA2C ADRA2B GABRQ GABRP GABRD GABRE TLR10 MET P2RX5 P2RX1 CXCL16 MTNR1B ADRA1B TBXA2R ADRA1A MERTK ADRA1D MTNR1A CLDN4 CLDN3 GABBR1 GABBR2 PAX8 CSF2RB TIE1 PTGER1 PTGER2 PTGER3 PTGER4 M6PR TAS2R16 CHRM5 TAS2R13 ADRB2 TAS2R14 ADRB1 CHRM4 CHRM3 CHRM2 SIGLEC8 IGF2R CHRM1 GPR17 TSHR PTAFR ACVR1 TAS2R10 TAPT1 OXTR IGF1R HRH1 ANXA9 HRH3 HRH2 DNER TAS2R43 CD4 KLRAP1 EBP FLT1 FLT3 FLT4 FZD10 EPOR DMBT1 OPRD1 GPR128 GPR126 GPR125 GPR124 IL6ST GPR123 EFNA3 TMEM11 LILRA1 CLEC4A CHRNA5 CHRNA4 CHRNA7 CHRNA6 CRY1 CHRNA1 CHRNA3 CHRNA2 C5AR1 CD3G GPR139 EFNB3 GPR133 GPR135 HTR4 OR1D2 OR1D5 CRHR1 CRHR2 LILRB5 LILRB3 HTR7 HTR6 PDGFRL PDGFRA PDGFRB EFNA4 GPR144 TRHR BDKRB1 BDKRB2 GPR143 EPHB2 LGALS3BP EPHB6 CD69 BAI1 BAI2 BAI3 OR2C1 CELSR3 AGER SLAMF1 KDR EPHA5 NPY NTRK1 CHRNB4 CHRNB2 IL5RA CHRNB1 GHSR GRK1 NRP2 TAS2R1 MCHR1 CCKAR NRP1 ACVRL1 TAS2R4 IL27RA TAS2R5 TAS2R3 TAS1R3 TAS1R1 TAS1R2 ASGR1 ASGR2 TAS2R9 TAS2R8 TAS2R7 XCR1 ICAM1 TPRA1 CCKBR CD160 NFAM1 GRM1 GRM5 TNFRSF10A CLEC1A GRM4 TNFRSF10C GRM3 GRM2 OR2H2 TNFRSF10D GRM8 GRM7 GRM6 CLEC1B AVPR2 LANCL1 GCGR IL10RB IL10RA CLEC2D FZD9 FZD8 PTPRZ1 NPR2 BRS3 FZD3 PTGFR FZD4 FZD7 FZD6 ABCC9 GRIA2 GRIA1 ABCC8 OPN4 VLDLR F2RL2 F2RL3 PLXNA1 GABRB3 GABRB2 GABRB1 VIPR1 VIPR2 GHRHR IL31RA SCTR GP6 ROBO1 ELTD1 GLP2R SPN PLXNB1 TNFRSF14 IGSF6 KIR2DL4 FGFR1 FGFR4 IL22RA1 CNR1 CNR2 CSF1R GABRA1 RYK EMR1 EMR4P EMR3 EMR2 SCARA3 IL3RA IL22RA2 OPCML TACR3 TACR2 TACR1 SORL1 BCAM GNRHR DDR2 ACVR1C CD97 ACVR1B PTH1R CALCRL IFNGR2 IFNGR1 ALK NCR2 FSHR IFNAR1 DDR1 IFNAR2 ACVR2A ACVR2B TNFRSF25 TNFRSF8 TNFRSF4 SCARF1 TNFRSF1A TNFRSF1B TNFRSF18 IL2RG GP1BA MR1 CRIM1 PTPRB PTPRC IL2RB PTPRD PTPRE LTK IL2RA PTPRA CXCR2 GPR110 OR3A1 GPR113 GPR114 GPR111 GPR112 GPR115 GPR116 F2R | |
| VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY SCN1B SCN2B SCN2A PKD2 SCN9A SCN4B SCN11A SCN7A CACNA1S SCN5A SCN4A | |
| PROTEIN_KINASE_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_KINASE_REGULATOR_ACTIVITY ALS2 CDK5R1 FGF13 AFAP1L2 SFN MBIP CXCL10 PRKAR2B AGTR2 CDKN2A CDKN2B HEXIM2 CDKN2C HEXIM1 PPP1R1B CDKN2D CD24 DNAJC3 APC ELP4 ELP3 IKBKAP SOCS3 MADD TAOK3 PKIG SOCS1 PKIA CAMK2N1 SH3BP5 CDKN1C GMFB CDKN1A CDKN1B GMFG PRKAR1A MAPK8IP2 GHRL MAPK8IP1 | |
| PHOSPHOLIPASE_C_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOLIPASE_C_ACTIVITY F2RL2 C3AR1 CASR PDIA3 CCKBR BDKRB2 EDNRA CHRM5 PLCE1 CHRM3 CCR5 CHRM1 PLCH1 PLCD1 PLCB2 | |
| LIGAND_GATED_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/LIGAND_GATED_CHANNEL_ACTIVITY ORAI1 SHROOM2 GLRA1 GLRA2 CNGB1 ZACN CHRNA4 CHRNA7 SCNN1G CHRNA6 SCNN1B HTR3A CHRNA1 HTR3B SCNN1D CHRNA3 CHRNA2 TRPC1 TRPC4 GLRB TRPC3 TRPC5 CFTR CNGA3 STX1B KCNA10 ACCN1 P2RX4 P2RX7 P2RX1 P2RX3 RYR3 P2RX2 CHRNB4 RYR1 CHRNB3 RYR2 CHRND CHRNB2 CHRNE | |
| RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY ALS2 ARHGEF3 ARHGEF2 DOCK2 ARHGEF1 TIAM1 PREX1 SOS1 PREX2 FARP1 ARHGEF11 FARP2 | |
| DOUBLE_STRANDED_DNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/DOUBLE_STRANDED_DNA_BINDING XRCC5 HLF HMGB2 MRE11A XRCC6 MLH1 ZNF638 KIN YBX1 ERCC5 CGGBP1 SAFB PMS2 NTHL1 FEN1 RBMS1 TERF1 MSH6 SATB1 RAD51AP1 MTERF MSH3 MSH2 TP53 APTX SMAD2 IFI16 CSDA RAD51 PURA HNRPDL PNKP | |
| SMALL_GTPASE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SMALL_GTPASE_BINDING FGD2 ALS2 FGD1 RAB3GAP1 RTKN ABCA1 CDC42EP2 RANBP9 DMXL2 IPO5 RAPGEF6 RANBP3 RANBP1 RANBP2 GOLGA5 FGD5 FGD6 CDC42EP5 FGD4 PARD6A RILP ARHGEF2 RALBP1 ARFIP2 IPO9 IPO8 DOCK4 PLCE1 SGSM3 IPO7 CYFIP1 GGA2 GGA3 | |
| PATTERN_RECOGNITION_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PATTERN_RECOGNITION_RECEPTOR_ACTIVITY MARCO PGLYRP4 PGLYRP2 PGLYRP3 PGLYRP1 TLR2 COLEC12 CLEC7A CD14 DMBT1 | |
| OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS ACOX2 GCDH ACADSB ACADM PPOX DECR1 ACADL ACOX3 SDHA ACADVL BLVRA AKR1C2 IVD CPOX DHCR7 BLVRB SDHD ACAD8 SRD5A2 MECR AKR1C1 DHCR24 RETSAT | |
| ATP_DEPENDENT_DNA_HELICASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ATP_DEPENDENT_DNA_HELICASE_ACTIVITY XRCC5 DHX9 RECQL PIF1 G3BP1 XRCC6 CHD2 CHD1 RUVBL2 CHD4 CHD3 | |
| TRANSCRIPTION_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSCRIPTION_FACTOR_ACTIVITY SLC2A4RG CDX2 STAT5A MORF4 STAT5B HIRA RORB PTTG1 CITED2 TAF5L FLI1 PHTF1 FOXS1 PITX2 PHOX2B ZNF45 NKX2-6 KDM5B RXRA YY1 KDM5A ZHX1 ZHX2 ZHX3 HNF4G TBR1 UHRF1 NME2 MTF1 HNF4A ZNF238 JUN FOXG1 MNT TGIF1 SHOX PRDM1 SUPT6H ZNF132 ZNF133 TFCP2L1 MYEF2 MYBL2 MYT2 DRAP1 LHX6 MAML3 TCF4 TCF3 NKX2-5 TCF25 NR1H4 PLAGL2 PLAG1 DMBX1 IKZF4 ZBTB48 YEATS4 KLF7 IKZF3 KLF12 KLF9 KLF10 CREBBP KLF11 TFCP2 UBP1 GAS7 USF2 DLX3 DLX2 NR1I3 ZNF217 RNF4 DLX6 TRPS1 AIRE TCF19 RBPJ KLF1 ZNF219 FOXI1 ZFHX3 TCF15 BACH1 HNF1B ELF1 LZTS1 HNF1A EVX1 FOXA3 TBX22 TBX21 PPARG SPI1 ZNF155 NFKB1 ZEB1 NFKB2 GLI2 GLI3 YBX1 ZBTB38 HSF1 HSF2 HSF4 MYC MSL3 NR2F1 BATF3 SNAPC5 AR SNAPC2 SNAPC4 GTF2H4 ZNF142 TP53 MXD1 MBD1 ZNF140 ZBTB25 MYCN SLC26A3 TAF13 PFDN1 ZNF137P CLOCK ZNF274 MECOM SCML2 SCML1 ZNF367 ZNF35 EHF ZBTB17 ZNF175 ZNF174 STAT6 ZFP36L2 STAT4 XBP1 TADA2A GBX2 ETV1 AATF SUPT4H1 FOXD2 ETV6 FOXD1 ETV5 FOXD4 SIM1 FOXD3 SIM2 ZNF263 MYF6 LZTR1 LMX1B TRIM29 HCLS1 TBX5 TRIM28 TBX4 MYF5 AFF4 TBX1 TRIM25 AFF1 STAT1 TRIM22 MSRB2 STAT3 TP73 RLF ZNF157 TADA3 PPBPL2 BNC1 NEUROD2 FOXE1 PHF5A NR5A2 ZNF256 FOXE3 CIR1 HNRNPAB MYOD1 LMO1 THRA LMO4 ARNT2 FOXO3 FOXO4 ZIC1 CNOT7 CBFB GATA1 BATF GATA2 ATOH1 TARDBP GATA3 HOXC5 GABPB2 POU5F1B RELA RELB GABPA ZNF189 FOXN2 HES6 TRERF1 SP140 AHR HHEX PA2G4 HIF1A EP300 TCFL5 ZNF197 TFAP2B EDF1 NFE2L1 NFE2L2 TFAP2C NFE2L3 MYNN SMARCA4 CNBP HMGB2 CCRN4L TFAP4 SOX5 ELK1 SOX4 ATF1 NR2C2 ARNT TFEC HOXA7 RUNX1 ATF6B RUNX3 CREBL2 TFDP1 SREBF1 NFE2 EPAS1 TAF5 FOXA1 NEUROG1 GSC2 FOXP3 VAV1 ATF6 ATF4 GCM1 ATF3 HDAC2 HDAC1 PHF1 SALL1 RFX1 RFX3 MAFA SCMH1 E2F1 ZNF85 POU6F1 SOLH AEBP1 E2F3 FOSL2 CELF3 E2F4 ARID4A POU6F2 PAX6 CTCF ZNF202 PAX3 BUD31 FEV FUBP1 MAX PCGF2 HEY1 POU5F1 PCGF6 PAX7 HEY2 PAX8 POU4F3 POU4F2 POU4F1 E4F1 NFIL3 RBPJL FOSL1 ALX1 NFX1 EGR1 NANOG EGR3 EGR2 SOX13 SOX14 DMRT1 RUNX1T1 DMRT2 ESR2 RB1 MSC HMGA1 UBN1 PURA NR3C2 NFYC NFIX NFYB NR3C1 NFYA POU1F1 HIC1 NPAS1 TFAM NPAS2 TSC22D3 HAND1 HAND2 POU2F2 POU2F1 POU3F4 NFAT5 POU3F3 POU3F2 MYOG POU3F1 NFATC2 ENO1 NFATC1 FOXL2 FOXL1 CREB1 CBL RCAN1 CREB5 IRF9 SP1 IRF8 ZRANB2 NFIC SCAND1 NFIB | |
| ENDONUCLEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ENDONUCLEASE_ACTIVITY RPP38 MRE11A DICER1 N4BP2 ERCC5 ANG RNASE8 DBR1 RPP30 ERCC4 APEX1 NTHL1 ERCC1 FEN1 EXO1 RNASE1 MBD4 RAD50 DNASE2 POP1 ERN2 POP4 OGG1 POP7 RPP40 | |
| PDZ_DOMAIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PDZ_DOMAIN_BINDING CLCN3 CADM1 NOS1AP SLC22A12 CCDC88C TBC1D10A USHBP1 CFTR PTEN DOCK4 SSTR2 GRM7 PDZK1 USH2A | |
| TRANSMEMBRANE_RECEPTOR_PROTEIN_PHOSPHATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSMEMBRANE_RECEPTOR_PROTEIN_PHOSPHATASE_ACTIVITY PTPRB PTPRJ PTPRK PTPRC PTPRD PTPRE PTPRM PTPRF PTPRG PTPRZ1 PTPRN2 PTPRH PTPRA PTPRR PTPRS PTPRT PTPRU PTPRN PTPRO | |
| EXONUCLEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/EXONUCLEASE_ACTIVITY EXO1 EXOSC7 ENPP2 ENPP3 MRE11A EXOSC2 TREX2 APTX TREX1 RAD9A WRN RAD50 ISG20 RAD1 REXO2 APEX1 XRN2 FEN1 ERI1 | |
| ACTIN_FILAMENT_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ACTIN_FILAMENT_BINDING SHROOM1 LIMA1 SHROOM2 ARPC4 ESPN EZR PLS1 EGFR MYO6 ACTN4 NEXN MYH9 FLNA UXT MAP1S SVIL SCIN MYO16 CYFIP1 MARCKS SPTA1 DST LRPPRC MYH10 SPTB | |
| CALCIUM_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CALCIUM_CHANNEL_ACTIVITY ORAI1 TRPV1 CACNB1 CACNB2 CACNB3 CACNB4 CUL5 TRPV5 MS4A2 TRPV6 TRPC1 TRPC4 CACNA2D1 TRPC3 TRPC5 CACNG5 CACNG4 CACNG2 CACNG1 CACNA1S TRPM2 TRPM1 RYR3 CACNA1G RYR1 RYR2 CACNA1H CACNA1E CACNA1F CACNA1C CACNA1D CACNA1A CACNA1B | |
| ACETYLCHOLINE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ACETYLCHOLINE_BINDING CHRM5 CHRM4 ANXA9 CHRM3 CHRM2 CHRM1 CHRNB4 CHRNA5 CHRNA4 CHRNA7 CHRNB2 CHRNA6 CHRNB1 CHRNA1 CHRNE CHRNA3 CHRNA2 | |
| STRUCTURE_SPECIFIC_DNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/STRUCTURE_SPECIFIC_DNA_BINDING XRCC5 HLF XRCC6 MLH1 TERF2IP ZNF638 YBX1 FUBP1 IGHMBP2 CGGBP1 PCBP1 PMS2 RBMS1 SATB1 MTERF HNRNPA2B1 TP53 APTX IFI16 NR0B1 CSDA PURB PURA RAD51 HNRPDL PNKP XPC FOXC2 RAD23B HMGB2 MRE11A RAD23A WBP11 KIN POT1 RPA4 MYT2 RPA3 RPA1 RPA2 ERCC5 SAFB NTHL1 ERCC4 ERCC1 TERF2 FEN1 TERF1 MSH6 RAD51AP1 MSH3 SUB1 MSH2 TREX1 SMAD2 HNRNPA1 | |
| CYTOSKELETAL_PROTEIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CYTOSKELETAL_PROTEIN_BINDING MTSS1 TNNC1 VAPB CROCC PDLIM5 CAPZA1 IQGAP2 MYLIP TTN HOOK3 VCL NRCAM ANK1 PACSIN3 RAE1 APOE TARDBP PLS1 ABRA CEP290 EGFR DBNL MYO6 TWF2 ACTN4 KIF5B NCALD BAIAP2 ACTN1 ACTN2 POLB CTNNA1 MYH9 MARK4 SUN2 PKD2L1 JUP ARPC1A TNNT2 UXT TNNT1 CCR5 RHCG CGN CLIP1 FLII ARL8A ARL8B STMN1 DST LRPPRC ADD2 ADD1 SPTB GC SSH1 SSH2 MYO9B ANLN ARPC4 FXYD5 CAPZB ARFGEF1 PXN KATNA1 DMD CLASP1 CLASP2 CDC42EP3 GABARAPL2 GABARAPL1 HTT SPTBN4 BRCA2 MYOZ1 TNNI3 TRIM63 SYNE1 S100B HPCA SPTBN2 MYO16 TMOD2 TMOD3 SPTBN1 CYFIP1 MARCKS TMOD4 SPTA1 MYH10 TLN1 LIMA1 MYBPC1 WASF2 MYBPC3 NDE1 CXCR4 ANG MAPT CDK5RAP2 DLG1 PARVG DYNC1I1 ARHGEF2 CCDC88A ACTA1 RPH3AL PALLD NEXN FLNA RAB11FIP5 KIF1B ATG4D SMTN ATG4C ATG4A TPPP SCIN MAPRE1 PRNP ABLIM1 SHROOM1 SHROOM2 SHROOM3 RABGAP1 CALD1 ABI2 ABI1 ESPN TUBGCP3 SORBS3 TUBGCP6 EZR TUBGCP5 SORBS1 MEFV SORBS2 PKD2 CNN2 WIPF1 DCX SYNPO APC IPP BIRC5 RACGAP1 COTL1 CENPJ RHAG GABARAP LSP1 NRAP MAP1S SVIL MAPK8IP2 MAPK8IP3 KPTN MAPK8IP1 SPTAN1 | |
| DNA_DEPENDENT_ATPASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/DNA_DEPENDENT_ATPASE_ACTIVITY XRCC5 DHX9 RBBP4 PIF1 G3BP1 XRCC6 TTF2 RAD51 RECQL ERCC8 RFC3 ERCC6 BPTF SMARCAL1 CHD2 CHD1 RAD54B RUVBL2 SMARCA1 TOP2A CHD4 CHD3 | |
| AUXILIARY_TRANSPORT_PROTEIN_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/AUXILIARY_TRANSPORT_PROTEIN_ACTIVITY SRI KCNAB3 KCNAB2 KCNAB1 NPY2R NNAT ARPP19 ENSA KCNJ12 KCNMB1 KCNMB2 KCNS3 KCNS1 ADRA2A KCNE1 CHRNA7 NEDD4L CHP SGK2 SMAD3 TNNI3 KCNV1 TMPRSS3 NPY PDZD3 RSC1A1 | |
| POTASSIUM_CHANNEL_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/POTASSIUM_CHANNEL_REGULATOR_ACTIVITY SGK2 KCNAB3 KCNAB2 KCNAB1 ARPP19 KCNJ12 KCNV1 KCNMB1 KCNMB2 KCNS3 KCNS1 ADRA2A KCNE1 CHP | |
| PHOSPHOLIPASE_A2_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOLIPASE_A2_ACTIVITY PLA2G10 PNPLA3 PNPLA8 PRDX6 PLA2G1B PLA2G2A PLA2G6 PLA2G2E PLA2G4C PLA2G3 PLA2G4B PLA2G2D PLA2G5 | |
| MOTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MOTOR_ACTIVITY KIF23 MYL6 BBS4 KIF22 KIF4A MYO9B KIFC3 KIF2C DNALI1 DNAI1 MYL6B APPBP2 DYNC1I1 KIF3B MYO6 KIF11 MYO3A KIF5B MYO1E KIF5C GRIN1 MYH2 CENPE MYH9 DNAI2 KIF1B MYH13 MYH10 | |
| NUCLEOTIDE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NUCLEOTIDE_KINASE_ACTIVITY MPP1 MPP2 AK1 MPP3 DTYMK AK2 CASK AK5 PNKP TJP2 GUK1 DLG2 DLG1 | |
| AMINOPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/AMINOPEPTIDASE_ACTIVITY METAP1 METAP2 TRHDE METAP1D ANPEP NPEPPS ENPEP XPNPEP1 LNPEP BLMH TPP1 C9orf3 ERAP1 ERAP2 | |
| STEROID_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/STEROID_BINDING GC SHBG TSPO OSBP CAV1 ESR2 STARD3 SYP ALDH1A1 NPC2 APOA1 PGRMC1 APOF PGRMC2 CETP HSD17B4 AKR1D1 SCP2 | |
| STEROID_HORMONE_RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/STEROID_HORMONE_RECEPTOR_BINDING MMS19 YWHAH NCOA6 TGFB1I1 DDX54 NSD1 DAXX PPARGC1B NRIP1 PRPF6 | |
| PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY CDC14B PTPN22 TIMM50 PTPN21 PTEN DLGAP5 DLG1 PTPRJ PTPRK PTPRM PTPRF PTPRG PPAP2C PTPRN2 PTPRH CYCS PTPRR CILP PTPRS PTPRT PTPRU PTPRN PTPRO TPTE PPM1G PPP1CA PPM1D SBF1 PPEF2 PPEF1 LCK PPM1M CTDP1 PPP5C PPP2R2A PPP6C PPP2R3B PPM1A DUSP12 DUSP11 PPM1B MTMR3 PPP1R3D PPP1R3C DUSP13 PPP2CB PTPLA CTDNEP1 MTMR7 PPAP2B PTPRB PTPN7 PTPRC PTPN6 PTPRD PTPN9 PTPRE PTPN18 PTPN3 PTPN2 PTPRZ1 PTPN5 PTPN4 EPM2A PTPRA PTPN14 CDKN3 PTPN12 CDC25B PTPN11 DUSP5 DUSP4 DUSP3 DUSP2 DUSP1 PTP4A3 PTP4A2 PTPN1 DUSP8 DUSP7 DUSP6 | |
| EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY GLRB GLRA1 GLRA2 STX1B P2RX4 P2RX7 P2RX1 P2RX3 ZACN CHRNB4 CHRNA4 CHRNB3 CHRND CHRNB2 CHRNA7 CHRNA6 HTR3A CHRNA1 HTR3B CHRNE CHRNA3 CHRNA2 | |
| HORMONE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/HORMONE_ACTIVITY VIP CGA PPY CGB UTS2 EDN1 GAST NMB TSHB POMC TRH ADCYAP1 CCL25 CALCB RLN1 PTH QRFP AGRP PRLH UCN GIP STC2 GNRH1 GNRH2 IGF1 INHA INHBB GRP PTHLH GH2 INHBA GH1 AMH NPY PNOC PENK CRH NPPB GHRL STC1 PYY CORT SST CHGB | |
| SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY SERPINA10 SPINK5 SERPINH1 APP SERPINA7 SERPINA6 SPINT2 SERPINA5 AGT SERPINA4 SERPINB10 SERPINA2 SERPINB12 SPINT1 SERPING1 SERPINI1 SERPINI2 AMBP SERPINB9 SERPINB6 SERPINF1 SERPINB8 PI3 SERPINB7 SERPINB3 | |
| PROTEIN_SERINE_THREONINE_TYROSINE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_SERINE_THREONINE_TYROSINE_KINASE_ACTIVITY MAP2K1 EPGN MAPKAPK5 MAP2K3 MAPK14 MAPKAPK3 TGFA MAPK10 MAP2K7 MAP2K6 | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS RNMT PNMT EZH2 MGMT PRMT1 PRMT7 PRMT8 ATIC PRMT5 METTL1 TRDMT1 PEMT EED GCSH PCMT1 NSUN2 DNMT3B LCMT1 DNMT3A EHMT1 GATM SUV39H1 TPMT GART SUV39H2 SUZ12 COQ3 BHMT WHSC1L1 AS3MT DNMT1 EDF1 GAMT CARM1 NSD1 NNMT FBXO11 | |
| OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NADH_OR_NADPH http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NADH_OR_NADPH CYB5R3 CYB5R4 CYB5R2 DUOX2 PRDX3 NDUFS7 NDUFS4 NDUFS8 NDUFS3 NQO1 NDUFS2 NDUFS1 NQO2 NOX4 NOX5 NDUFA9 NOX1 NDUFA13 ECSIT GMPR CYB561 DHDH POR NNT CRYZL1 | |
| CARBOHYDRATE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBOHYDRATE_KINASE_ACTIVITY PFKL GNE PFKFB2 PFKFB1 HK2 PFKP HK1 PFKM KHK GALK2 GALK1 GCK PRPS2 XYLB PRPS1 | |
| CHLORIDE_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CHLORIDE_CHANNEL_ACTIVITY FXYD1 CLCN1 GLRB CLCN3 CLCA2 FXYD3 CLCA1 CLCN2 CLCA4 GLRA1 GLRA2 CLCNKA CLCNKB CFTR BSND BEST1 NMUR2 PKD2 CLCN4 | |
| HEMATOPOIETIN_INTERFERON_CLASSD200_DOMAIN_CYTOKINE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/HEMATOPOIETIN_INTERFERON_CLASSD200_DOMAIN_CYTOKINE_RECEPTOR_ACTIVITY IL1R1 IL22RA1 IL9R OSMR IL6ST CNTFR IL7R IL31RA IL12RB2 IL12RB1 IL10RB IL10RA IL4R CSF2RB IL15RA IL2RG IFNGR2 IFNGR1 GHR IL13RA2 IL2RB IL2RA LIFR IL6R IFNAR1 IFNAR2 CXCR2 GFRA1 EPOR IL5RA GFRA2 IL3RA IL22RA2 | |
| CARBOXYLESTERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBOXYLESTERASE_ACTIVITY PNLIP ACHE PPME1 APOC2 AOAH PLA2G1B PLA1A MGLL CES1P1 LPL PNLIPRP1 CES2 PNLIPRP2 CES1 PLA2G10 PLA2G15 LGALS13 LYPLA1 PNPLA3 PNPLA8 PRDX6 LIPG PLA2G2A PON2 PLA2G6 PLA2G3 PLA2G4C PLA2G2E PLA2G2D PLA2G4B LIPE PLA2G5 LIPF | |
| RHO_GTPASE_ACTIVATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/RHO_GTPASE_ACTIVATOR_ACTIVITY RALBP1 PREX1 ARHGAP27 MYO9B ARHGAP29 PREX2 THY1 DOCK4 ARHGAP4 CDC42EP2 ARHGAP5 GMIP SOS1 OPHN1 ARAP1 ARAP3 ERRFI1 ARHGEF10L ARHGAP10 | |
| STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON http://www.broadinstitute.org/gsea/msigdb/cards/STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON LOR GFAP CD2AP VILL ANK1 DES MAPT PLS1 MSN TUBG1 INA ACTA1 BICD1 CCDC6 ARPC1B KRT19 KRT17 ACTL7A ACTL7B KRT15 KRT14 DSP DST ADD3 KRT6B VIM ARPC4 ARPC5 EPB41L4B KRT9 SORBS3 ARPC3 KRT5 ARPC2 SORBS2 DMD PPL KRT1 TUBE1 KRT2 ACTL6B AGRN NEFL NEFM HIP1 ACTB EPB41 EPB42 SPTBN4 BFSP1 KRT31 BFSP2 CYLC2 SPTBN2 SPTBN1 SPTA1 SPTAN1 | |
| PATTERN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PATTERN_BINDING CHIA PGLYRP1 HDGF TLR2 FGF10 POSTN FSTL1 PF4 MDK CHIT1 NOD2 NOD1 PGLYRP4 ANG PGLYRP2 SERPINA5 IMPG2 PGLYRP3 ZNF146 APOA5 ACAN ODZ1 FGFBP1 THBS2 THBS4 LPL TNXB COL13A1 CHODL COL25A1 STAB2 NLRP3 RPL29 LRPAP1 TNFAIP6 PODXL2 LAYN VEGFA AAMP HBEGF TGFBR3 VCAN EPYC CD14 HABP2 | |
| INTERLEUKIN_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/INTERLEUKIN_RECEPTOR_ACTIVITY IL2RB IL1R1 IL9R IL2RA IL6ST IL6R IL7R IL12RB2 CXCR2 IL12RB1 IL10RB IL4R IL10RA CSF2RB IL15RA IL2RG IL5RA IL3RA IL22RA2 IL13RA2 | |
| TRANSCRIPTION_FACTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/TRANSCRIPTION_FACTOR_BINDING HIRA MED24 MED23 HDAC7 MED21 MXI1 RFXAP MED26 MED27 PQBP1 RARA TBPL1 PITX2 PHOX2B PCBD1 RXRB YY1 TAF4B RXRA MECP2 MED12 MED14 MED13 PPARGC1A PPARGC1B MTF1 MED16 PIAS3 ABT1 MED17 VGLL1 MNT TGIF1 PIAS1 TGFB1I1 KAT2A MYBBP1A ZNHIT3 TRAPPC2 ENPP2 CRTC1 TFCP2L1 NFKBIB FIGLA NFKBIA MYEF2 DRAP1 PIR MAML3 BCOR NR1H4 NR1H3 MDFI UTF1 KLF7 KLF12 TP53BP2 SUB1 MAML1 CREBBP MAML2 RYBP SMAD2 C19orf2 PMF1 UBP1 TONSL OASL NR1I3 NR1I2 NUP62 JAZF1 NCOR1 NCOR2 ZBTB32 HTATIP2 COPS5 ELF3 TSG101 NFKB2 ZEB1 HSBP1 KCNIP3 HSF2 GPX3 CREG1 BRD7 HSF4 NR2F2 NR2F1 BRD8 BATF3 CTBP1 GMEB1 SF1 TLE1 FOSB MXD1 MBD1 FLNA MXD4 JMY MED6 SLC26A3 MED7 MED4 NAB2 ZNF136 PFDN5 BRDT FOXC1 SIAH2 SRCAP NSD1 MED1 YWHAZ ZNF274 NMI SUFU NR1D1 TADA2A BCL3 PEX14 TRIP11 TRIP12 TRIP13 RNF19A TRIM28 TRIM24 TRIM22 STAT3 YAF2 GSK3B APBB2 RBM14 APBB1 CIR1 NR5A1 MMS19 MYOD1 THRB STK36 LMO4 ARNT2 CBX4 FOXO4 RBFOX2 AIP HOXC6 CDKN2A MYOCD SMARCD2 CASP8AP2 MDFIC SMARCD3 SND1 SMARCD1 TFB2M KAT8 KAT6B KAT6A CIITA BCL10 POU2AF1 ZNF593 RELA GABPA RELB HDAC11 NR0B2 HES6 CSDA TRERF1 STK4 DDIT3 JUNB EP300 SMARCE1 TRIM32 TFAP2B RIPK3 TFAP2A EDF1 NFE2L1 NFE2L3 SMARCA2 SMARCA4 EID1 HMGB1 TFAP4 ELK3 TRRAP SRF NR2C2 ATF2 ARNT TCERG1 MEIS2 ELK4 TFEC NPM1 TFDP2 TAF9 SKIL RNF14 TFDP1 SSX1 PARD6A TAF4 NFE2 TRIP4 EPAS1 HTT MAFB TAF7 SAP18 GTF2A1L SNW1 FOXP3 ATF6 HDAC5 ATF5 HDAC4 HDAC3 PSMC5 GCM1 ATF3 HDAC2 HDAC1 PSMC3 DYRK1B SMARCC1 GTF2F1 SMARCC2 HDAC9 DDX54 HDAC8 ZNF85 E2F1 NBN E2F6 PRRX1 CTCF PAWR FEV TMF1 SAP30 MAX PLRG1 GTF2A1 E4F1 MKL2 NRG1 NFIL3 ALX1 SOX10 LDB1 ZFX LDB2 ESR2 HMGA1 MSC PURB PRPF6 PURA NRIP1 BPTF ZMIZ2 HIPK2 NCOA6 ZFPM2 JMJD1C CARM1 COMMD7 TDP2 NFYC HCFC1 TRIB3 HCFC2 CALCOCO1 ECD NFATC4 ERCC3 APEX1 ENO1 CEBPA ERF PDCD11 VHL DTX1 CEBPG CREB1 CENPF DRG1 PPP1R13L SIRT2 MED30 DR1 THRAP3 SP4 ARHGAP35 KAT2B ID4 IRF3 ID3 FAF1 NFIA | |
| PROTEIN_KINASE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_KINASE_BINDING BCAR1 HINT1 PDLIM5 FOXO3 PRDX3 LATS1 NOD2 CDKN2A CEP250 CDKN2B CDKN2C CDKN2D CDK5RAP2 TOP2B FIZ1 MAP2K7 TOP2A DLG1 ADAM9 KIF13B BCL10 IRAK1 ADAM10 ZC3HC1 CCDC88A RELA SOCS1 PICK1 PTPRR RAD9A SPDYC SPDYA CCND3 LAX1 LCK AKAP5 AKAP7 MAP3K13 MAP3K12 AKAP3 AKAP4 AKAP12 TRIB3 ITGB2 AKAP11 LLGL1 SQSTM1 CD4 CD24 TPRKB APC PTPRC CAMK2N1 YWHAG RPS6KA4 AVPR1B MAPK8IP2 AVPR1A MAPK8IP3 GRK5 MAPK8IP1 FAF1 | |
| TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY NRP2 FGFR1 FGFR4 NRP1 ERBB4 ERBB3 EFNA3 PTK7 DDR2 EPHB2 IGF1R EPHB6 MUSK TEK TIE1 INSR CRIM1 CSF1R EGFR TYRO3 FLT1 LTK EFNB3 FLT3 RYK FLT4 MET AXL TRIM27 ALK KDR EPHA5 DDR1 NTRK1 IGF2R PDGFRL ROR1 PDGFRA ROR2 PDGFRB EFNA4 MST1R MERTK | |
| PHOSPHOLIPASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOLIPASE_ACTIVITY F2RL2 C3AR1 CASR ENPP7 PDIA3 BDKRB2 EDNRA PLCH1 PLA2G1B MGLL PLA1A PLCD1 PLCB2 PLD3 LPL PLD2 PLD1 PLA2G10 CCKBR PLA2G15 LGALS13 LYPLA1 PNPLA3 PNPLA8 PLCE1 CHRM5 CHRM3 CCR5 PRDX6 CHRM1 SMPD1 PLA2G2A LIPG PLA2G6 PLA2G2E PLA2G4C PLA2G3 SMPD4 PLA2G4B PLA2G2D PLA2G5 SMPD2 | |
| PROTEIN_HETERODIMERIZATION_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_HETERODIMERIZATION_ACTIVITY RAB3GAP2 VAPA VAPB HEXA HEXB ARNT2 BNIP3 SAE1 SDCBP2 TPD52 TGFB2 BAK1 APOB APOA2 TYR APOE PRMT8 TOP2B SUPT5H TOP2A EGFR PPP2R1B PPP2R1A CD3G CD3D CD3E SCUBE1 TP53 TARBP2 HIF1A EREG TIMELESS IL12A SDCBP IL12B TYRP1 CLCN3 MCL1 ERBB4 ERBB3 ERBB2 KATNB1 APOC2 RRAGA PDSS1 PDSS2 RRAGC DGKD ROPN1B TAP2 KATNA1 BCL2 PPP2CA NPM1 TAP1 SUPT4H1 CEBPG CENPF BIRC5 TPD52L1 SMC2 ABCG4 SMC3 ABCG1 SMC4 CD1D NAE1 ABCG8 ABCG5 BAX NOTCH4 UBA3 BNIP3L TRPC4AP PPP2R4 SMC1A BARD1 | |
| OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS ALDH8A1 BCKDHA ALDH6A1 ALDH5A1 BCKDHB ADH5 ALDH3B2 OGDH ALDH3B1 PDHB ALDH3A2 ALDH3A1 GAPDHS ALDH1A1 ALDH1A2 ALDH7A1 ALDH1A3 AOX1 ALDH2 ALDH4A1 PDHA2 ALDH9A1 | |
| ATPASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ATPASE_ACTIVITY XRCC5 ATP1B1 ATP1B3 ATP1B2 SNRNP200 XRCC6 TAPBP ATP2B1 ATP2B3 DDX17 DDX18 ATP2B4 DDX23 DHX38 DDX25 VPS4B DDX21 DDX20 MYO3A ABCB11 PICK1 MYH7 MYH6 MYH9 CLPX RFC3 ATP2C1 SMARCAL1 SMARCA5 SMARCA1 DDX39A MYL6 ABCA8 FXYD2 KATNB1 MYO9B ABCA2 ATP6V1B2 ABCA3 ATP6V0C DDX3X KATNA1 DDX43 DHX8 DHX9 PIF1 MYO1E ATP11B ABCB7 ABCG1 ABCG2 ATP7A PSMC6 DDX56 PSMC5 ATP2A2 PSMC4 VCP ATP2A3 PSMC1 ATP2A1 CCT8 RAD54B DDX54 ATP7B MYH10 ABCF1 ATP6V0E1 RSF1 PEX6 PEX1 ATP8B1 TOP2A RBBP4 ATP4A ATP4B RALBP1 G3BP1 TTF2 RAD51 ATP6V1C1 RECQL EIF4A3 KIF1B BPTF RUVBL2 RUVBL1 SKIV2L WRNIP1 INO80 ERCC8 ERCC6 CHD2 CHD1 ABCD3 ABCD4 ERCC3 CHD4 CHD3 MSH6 UPF1 MSH2 ATP1A3 ATP1A4 ATP1A1 ATP1A2 ABCC3 KIF20B ABCC1 PPP2R4 ABCC2 ABCC6 | |
| METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY KCNC1 SLC9A7 KCNC4 KCNC3 ATP2B1 ATP2B3 CUL5 ATP2B4 KCNK7 KCNK6 KCNK5 CHRNA4 MS4A2 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 KCND3 SCN2B ABCB11 SCN2A ATP2C1 RYR3 RYR1 RYR2 SLC40A1 KCNMB3 KCNMB4 ORAI1 SCN1B KCNA2 KCNA1 KCNA4 CACNB1 KCNA3 CACNB2 CACNB3 KCNA6 CACNB4 KCNA5 KCNJ3 KCNMB1 KCNMB2 KCNJ1 KCNS3 SLC11A2 KCNS1 GAR1 SCN9A SLC30A4 SLC30A5 SLC30A3 SLC31A2 SLC31A1 TRPC1 CACNA2D1 TRPC4 TRPC3 KCNB2 TRPC5 KCNK1 CACNA1S KCNK3 KCNK4 KCNJ5 KCNJ4 P2RX4 P2RX7 KCNJ6 SLC4A11 P2RX1 ATP2A2 ATP2A3 P2RX3 ATP2A1 CACNA1G CHRNB4 CACNA1H CHRNB3 CHRND CHRNB2 CACNA1E CACNA1F SLC13A4 CACNA1C CACNA1D CHRNE CACNA1A CACNA1B KCNH1 KCNK17 KCNJ15 TRPV1 KCNJ10 KCNIP2 KCNJ12 KCNJ14 KCNK10 KCNQ5 KCNQ3 FXN CCT8L2 TRPV5 SCN7A TRPV6 KCNQ2 KCNQ1 KCNG2 CACNG5 CACNG4 CACNG2 CACNG1 TRPM2 TRPM1 KCNA10 SCN11A KCNH2 KCNH3 KCNH4 CLDN16 SHROOM2 PKD2 KCNE1 KCNE2 CCS SCNN1G HTR3A SCNN1B SCN5A HTR3B SLC39A2 SCNN1D SLC8A1 NOX5 ITPR3 ITPR1 TRAPPC10 ITPR2 KCNN4 ACCN1 ACCN4 KCNN3 KCNN2 SCN4B ABCC8 SCN4A | |
| HYDROGEN_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/HYDROGEN_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ATP6V0E1 COX11 SLC9A7 SLC9A6 UQCRC1 SLC9A5 COX10 SLC9A3 SLC9A2 COX7B ATP6V1B2 COX7A2L COX5A COX5B ATP6V0C COX15 ATP4A COX7A1 ATP4B COX8A COX4I2 COX4I1 CYB5A ATP6V1C1 NNT UQCRH SURF1 | |
| PROTEIN_C_TERMINUS_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_C_TERMINUS_BINDING ITGB3BP XRCC4 HRAS CADM1 PEX6 SAE1 SDCBP2 CTNNB1 DFNB31 DAB2 TRIM3 PEX1 DLG4 TOP2B CSK TOP2A DLG1 BCL10 CTBP1 MAGI1 BAIAP3 BAIAP2 PICK1 TOPBP1 PFKM OPTN LIG4 CDK7 LDLRAP1 SLC9A3R2 NCL PRKCD RAD51 EFHC1 EP300 ITGB1BP1 LCK HSPB7 PEX26 SIAH1 MAPRE1 DST USP7 CAV3 SNX17 MRE11A COIL HIC2 ERCC6 PEX16 PKD2 TAF9 PEX12 PABPC1 ERCC3 ERCC4 NEFL MLLT4 ERCC1 ERCC2 YEATS4 MSH2 CENPF ATXN1 ATXN2 SP1 SMARCC1 RBFOX1 SMARCC2 ABL1 PDZK1 PDZD3 CACNA1B | |
| GTPASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GTPASE_ACTIVITY GNA13 SEPT5 SEPT4 GNA14 GNA15 RAB9A GNA11 GNA12 EIF5 RRAD RAB1A DIRAS3 RAB28 RRAS GNG3 RAB27B MX2 RAB27A GTPBP2 GTPBP4 NUDT1 OPA1 NCF1 RAN EFTUD2 EIF2S3 RND2 RND3 AGAP2 RAB13 SEPT9 RAB7A GNAI3 GNAI2 GNAI1 MRAS ARFRP1 ARF6 ARF5 RRAGC RAC2 RAC3 RAC1 RAB6C RAB7L1 RAB33A RERG GNGT1 ARF1 ARF3 ARF4 RAP1A RHEB GNAZ RAB5B RAB5C CDC42 ARHGAP5 RASL10A RHOA RHOB RHOC RAB6A RHOD RHOG ARL1 RAP2A RAB4A GNAL GNAQ GNB2 GNB1 RRAS2 RAB5A GNAS GNB3 ARL4D RASD1 ARL4C ARL4A RAB3A RAB3B RAB3D GNG11 RAB11B TGM3 RAB2A GNAO1 DNM1L TRIM23 RABL2A RABL2B RAB31 RAB30 GSPT1 GNG10 RAB35 RAB22A DNM1 | |
| INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC9A7 ATP6V0E1 COX11 UQCRC1 SLC9A6 SLC9A5 COX10 SLC9A3 SLC9A2 COX5A COX5B ATP2B1 ATP2B3 ATP2B4 FXN SLC22A3 COX15 ATP4A ATP4B ABCB11 COX4I2 COX4I1 CYB5A ATP6V1C1 NNT RHCG ATP2C1 UQCRH SURF1 SLC40A1 CLDN16 KCNA1 COX7B COX7A2L ATP6V1B2 SLC11A2 ATP6V0C SLC30A4 SLC30A5 CCS SLC30A3 SLC31A2 SLC31A1 SLC39A2 SLC8A1 COX7A1 COX8A ITPR3 RHAG ITPR1 TRAPPC10 ITPR2 ACCN4 ATP2A2 ATP2A3 ATP2A1 SLC13A4 ABCC8 | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS SGMS2 SGMS1 CLK1 MED21 MAP3K7 MAP3K6 MAP3K5 MAP3K4 CLK3 CLK2 MAP3K9 ILK MAP3K8 PIK3C3 PIK3CA TLK1 TLK2 MAP2K7 MAP2K6 PIK3CG TYRO3 TNIK ROCK1 ROCK2 PIK3CB DPAGT1 MARK4 MARK1 NME6 MARK2 NME4 MAPK1 NME5 NME2 EIF2AK1 MAPK6 NME1 MAPK4 ROR1 MAPK9 ROR2 MAPK8 MST1R MAPK7 EIF2AK2 EIF2AK3 EIF2AK4 ERBB4 ERBB3 ERBB2 MUSK MAP2K1 TAOK2 MAP2K3 TGFBR1 NIM1 TAOK3 TGFBR2 SPHK1 DUSP21 ATM STRADA CDC42BPG CDC42BPA TNK2 CDC42BPB BCKDK NUAK2 PMVK LATS1 LATS2 USP14 TAF1L SRPK2 LYN PIK3C2A CDK1 PHKG2 PI4KA PI4KB DGUOK SRPK1 GTF2H1 MAST1 SIK2 RIPK1 BRDT TXK CMPK1 MKNK2 HK2 POLA1 MKNK1 HK1 DGKA SNRK DGKE DGKD PTK2B CKMT2 DGKG CERK PAPSS1 PAPSS2 PDK1 PDK2 BRD2 DGKQ PDK3 PDK4 TRIM27 CSNK2B AXL DGKK NADK DGKI RPS6KA5 RPS6KA3 CSNK1D RPS6KA1 RPS6KA2 CSNK1E EPGN GSK3B DGKZ SIK1 ZAK STK38 STK36 RPS6KB2 CSNK2A2 CSNK2A1 INSR EGFR TWF1 PDXK RPS6KC1 TESK1 TESK2 NMNAT1 PHKA2 STK16 CCL2 STK11 STK10 MAPKAPK5 PHKA1 MAPKAPK3 PTK7 MAPKAPK2 CCL4 POLE4 POLE2 POLE3 PTK6 TEK PCYT1A DYRK2 PCYT1B STK19 NR4A3 TAF1 MET SMG1 GLYCTK TRNT1 IKBKE POLD4 PLK4 PLK3 PLK1 POLD1 DYRK1A MERTK PTGES3 PINK1 SKAP1 DKC1 TIE1 POLG2 PCYT2 DLG2 DLG1 SGK1 SGK2 SGK3 LIMK2 LIMK1 CDK9 CDK7 PBK CDK5 NEK11 CDK2 CDK3 GAK HUNK IGF2R PKM2 PKLR ERN1 ERN2 UGP2 ACVR1 XYLB PGS1 BRSK2 DCK BRSK1 IGF1R FLT1 FLT3 FLT4 TSSK1A GCK IPPK EFNA3 PRKX PRKY PRIM1 WNK4 COL4A3BP PRIM2 BCR POLI EFNB3 POLH POLG POLE PIM1 WNK1 POLB WNK3 PIM2 WNK2 PNKP PDGFRL PDGFRA PDGFRB EFNA4 NEK4 NEK6 CHKA COASY TAB1 CDK5R1 NEK2 PFKFB2 PFKFB1 STK17B PXK STRADB CHEK2 STK17A TK2 UHMK1 TK1 EPHB2 EPHB6 VRK1 VRK2 POLQ UAP1 TRIO OXSR1 KDR EPHA5 POLRMT CKMT1A NTRK1 NRP2 NRP1 ACVRL1 ARSG CAMKK2 RNGTT CKB PDPK1 FXN TGFA SIK3 POLR1C CDS1 CKM ADK MAP3K10 CTDP1 MAP3K13 MAP3K12 MAP3K11 REV3L PIKFYVE POLR2E POLR2L POLR2J POLR2I KIT POLR2D GALK2 GALK1 THG1L CSNK1A1 POLR3G POLR3H POLR3K NLK MAPK11 MAPK10 POLR3C KHK TP53RK MAPK12 MAPK13 MAPK14 MAPK15 PGK1 CIT TJP2 PGK2 DTYMK TTK CASK ITPKB TTN PRKCB ITPKA DMPK PRKACG DNTT PRKACB MTOR CSNK1G2 CHPT1 STK4 STK3 MAP4K3 MAP4K4 MAP4K5 CDKL1 PI4K2A RIPK3 RIPK2 MVK RIPK4 PRPS2 KALRN PRPS1 FGFR1 FGFR4 GNE MAP4K2 MAP4K1 IRAK3 CEPT1 LMTK2 STK38L CSF1R ITK RYK AK1 AK2 AK5 ULK1 CPNE3 GUK1 MYLK PIP4K2B PRKAG3 PRKAG1 DDR2 ACVR1C AKT1 ACVR1B PIGF PAK2 PIGG CDK10 PAK1 CHUK TERT AKT2 IRAK2 IRAK1 PFKL MPP1 MPP2 MPP3 PFKP PRKCI PRKCH MINK1 PRKCG PFKM PRKCE ALK DAPK2 DAPK3 XRCC6BP1 PRKD1 TYK2 ACVR2A DDR1 ACVR2B CRKL HIPK3 PRKD3 FRK PRKCZ TRIB2 TRIB1 N4BP2 EXOSC10 MAP3K3 MAP3K2 ETNK1 PIK3R3 CRIM1 PIK3R2 LTK TEP1 TSSK2 TSSK4 TSSK3 TSSK6 | |
| NUCLEOBASENUCLEOSIDENUCLEOTIDE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NUCLEOBASENUCLEOSIDENUCLEOTIDE_KINASE_ACTIVITY CMPK1 DTYMK DCK CASK TK2 TK1 N4BP2 DLG2 DLG1 MPP1 MPP2 AK1 MPP3 AK2 AK5 DGUOK NME6 NME4 NME5 PNKP NME2 NME1 ADK TJP2 GUK1 | |
| GTPASE_ACTIVATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GTPASE_ACTIVATOR_ACTIVITY DLC1 RAB3GAP2 PREX1 RAB3GAP1 RANGAP1 ARHGAP4 ARHGAP5 RAPGEF2 ERRFI1 BCR RALBP1 ARHGAP27 ARHGAP29 PREX2 THY1 BNIP2 OPHN1 ARFGAP3 RABGAP1 RAP1GAP PTPLAD1 SIPA1 MYO9B ARFGEF1 ALDH1A1 RASAL2 RASAL1 RGS11 CDC42EP2 RGS12 DOCK1 RASGRP3 GMIP SOS1 ARAP1 ARAP3 RASA3 RASA4 ARHGEF10L RASA1 RASA2 ABR VAV3 NF1 RACGAP1 RGS16 RGS14 DOCK4 RGS20 RGS1 RGS2 RGS3 ADAP1 RGS4 TSC2 RGS5 RGS6 CHN2 RGS9 ARHGAP10 | |
| PEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PEPTIDASE_ACTIVITY MASP1 MASP2 MMP9 THOP1 LGMN MMP8 PPP2R5C IDE RCE1 ENPEP MMP3 MMP2 USP53 HTRA2 HTRA1 PAPPA FAP CPA2 ERAP1 CPA3 ERAP2 CPA1 CFI CFD F11 F12 CAPNS1 F10 USP1 F9 F7 NPEPPS CPE TMPRSS11D F2 CLPP BACE1 CPD PGCP ADAMTS2 ACR CTSL2 CELA3A CELA3B KEL MME CTSL1 ACE ECE2 CTRC KLKB1 ZMPSTE24 CELA2B GGH FURIN TINAG APEH C9orf3 PAPPA2 CPB1 CPB2 ASPRV1 SOLH SPG7 KYNU AEBP1 METAP1 METAP2 CORIN PDIA3 UCHL1 ANPEP MMP28 MMP24 LNPEP CASP5 CASP6 LONP1 CASP3 MMP20 CASP9 TPP1 TPP2 CASP7 CASP8 USP12 USP11 LTF PRSS36 CASP1 USP16 USP15 USP14 DPP4 DPEP1 VCPIP1 USP13 PEPD GZMA UFD1L MMP17 GZMB MMP16 CTSS MMP15 MMP14 MMP13 MMP12 MMP11 PROC USP29 SENP2 CTSK CHMP1A BLMH SENP1 ATG4D PSEN1 CAPN11 ATG4C ATG4B ATG4A CTSO CTSE USP21 CTSD UCHL3 CTSB CTSH PMPCA CTSG USP7 PREP USP6 USP8 ECEL1 USP9Y USP2 USP5 USP9X SHFM1 APH1B USP4 PRSS1 C1R C1S PCSK2 REN PRSS2 PRSS3 TOR1A PITRM1 PCSK9 PGA4 PCSK7 PCSK6 HGFAC CAPN6 KLK8 CAPN5 MBTPS2 TRHDE KLK2 METAP1D CAPN9 KLK1 CAPN3 TMPRSS6 PLG XPNPEP1 CASP10 MMP23B CASP14 MEP1A ACE2 ELANE | |
| ION_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ION_CHANNEL_ACTIVITY KCNC1 KCNC4 KCNC3 CNGB1 CUL5 KCNK7 KCNK6 KCNK5 CHRNA4 MS4A2 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 KCND3 CLCA2 CLCA1 CLCA4 SCN2B SCN2A CNGA3 RYR3 RYR1 RYR2 FXYD1 KCNMB3 CLCN1 ORAI1 KCNMB4 FXYD3 CLCN3 CLCN2 SCN1B KCNA2 KCNA1 CACNB1 KCNA4 KCNA3 CACNB2 KCNA6 CACNB3 CACNB4 KCNA5 KCNJ3 KCNMB1 KCNJ1 KCNMB2 KCNS3 KCNS1 GAR1 ZACN SCN9A TRPC1 CACNA2D1 TRPC4 TRPC3 KCNB2 TRPC5 KCNK1 CACNA1S KCNK3 KCNK4 KCNJ5 P2RX5 KCNJ4 P2RX4 P2RX7 SLC4A11 KCNJ6 P2RX1 P2RX3 P2RX2 CHRNB4 CACNA1G CACNA1H CHRNB3 CACNA1E CHRND CHRNB2 CACNA1F CACNA1C CACNA1D CHRNE CLCN4 CACNA1A CACNA1B KCNK17 KCNH1 KCNJ15 KCNK15 GLRA1 TRPV1 TRPV2 GLRA2 KCNJ10 HVCN1 KCNIP2 KCNJ12 KCNJ14 KCNK10 KCNQ5 KCNQ3 CCT8L2 NMUR2 TRPV5 SCN7A TRPV6 KCNQ2 KCNQ1 KCNG2 TRPM5 CACNG5 CACNG4 CFTR CACNG2 CACNG1 STX1B TRPM2 TRPM1 KCNA10 BSND SCN11A KCNH2 KCNH3 KCNH4 SHROOM2 CLCNKA CLCNKB BEST1 PKD2 KCNE1 KCNE2 SCNN1G HTR3A SCNN1B SCN5A HTR3B SCNN1D GLRB NOX5 NOX1 KCNN4 ACCN1 ACCN4 KCNN3 KCNN2 SCN4B SCN4A | |
| SMALL_PROTEIN_CONJUGATING_ENZYME_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SMALL_PROTEIN_CONJUGATING_ENZYME_ACTIVITY DZIP3 RNF217 MYLIP WWP2 WWP1 FBXO22 ANAPC2 ANAPC5 ANAPC4 UBR3 UBE2H UBE2C BRAP UHRF2 HUWE1 UBE2K UBR5 UBE2M UBL4A DDB2 MDM2 FBXL6 AMFR ZER1 FBXL2 ANAPC10 ANAPC11 UBE3C STUB1 ERCC8 UBE2D3 UBE2D2 FBXW2 FBXO3 TRAF7 TRAF6 FBXO7 RNF144B CBL FBXO2 UBE2L6 CDC23 MALT1 PARK2 TRIM23 UBE2L3 BIRC3 ATG3 SMURF2 SMURF1 UBE2E2 UBE2E1 | |
| CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY USP7 CTSL2 USP6 SOLH USP8 PDIA3 USP2 USP9X USP5 LGMN UCHL1 USP4 CTSL1 CASP3 CASP9 CASP8 USP11 USP16 CASP1 USP15 USP14 USP13 CAPN6 CAPN5 CAPNS1 USP1 CAPN9 CTSS CAPN3 TINAG CASP10 BLMH CTSK ATG4D CAPN11 ATG4C CASP14 CTSO CTSB CTSH | |
| PROTEIN_DIMERIZATION_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_DIMERIZATION_ACTIVITY ALS2 RAB3GAP2 S100A6 SLC9A7 CADM3 NRBP1 CADM1 VAPA VAPB ARNT2 SAE1 TPD52 GDNF AGXT TGFB2 APOA4 BAK1 APOB NLRC4 APOA2 MAP3K5 PLOD1 APOE MAP3K9 CHRNA7 SUPT5H WWOX S100A1 EGFR CD3G CD3D ACTN4 CD3E NCF4 SCUBE1 KIAA1804 CST3 ACTN2 ACTN3 MYH9 STK4 STK3 HIF1A EIF2AK1 TIMELESS IGSF1 TFAP2B SDCBP TFAP2A CLIP1 ABAT ATPIF1 TFAP2C CAV2 CLCN3 SNX6 MCL1 ERBB4 ERBB3 ERBB2 KATNB1 APOC2 DSCAML1 RRAGA MYO9B PDSS1 PDSS2 RRAGC ADRB3 PVRL1 UPK1A KATNA1 PVRL3 NPM1 PVRL2 IL17F CDA GYS2 AIMP1 TCF3 CARD8 CUBN MLL CARD9 TAF5 SMAD4 S100A11 SMAD3 CIDEA TREX1 TPD52L1 FOXP3 ABCG4 ABCG1 ABCG2 FOXP2 ABCG8 ABCG5 S100B TSC2 NOTCH4 UBA3 MAFA SMC1A HEXA HEXB HPS4 NR6A1 HPS1 BNIP3 SDCBP2 CDSN TYR BOK PRMT8 TOP2B GOLGA5 TOP2A PPP2R1B PPP2R1A CCDC88A HSP90AA1 ADAM10 GZMA LDB1 TP53 AMBP INHBB XPA TARBP2 ADRB2 EREG IL12A MAP3K10 IL12B MAP3K13 MAP3K12 CLN6 AOC3 MAP3K11 TYRP1 NFS1 EEA1 ZBTB16 HPRT1 MOAP1 ERCC5 ANXA9 CEP57 SPRR2C SH3GLB1 ROPN1B DGKD TAP2 BCL2 PPP2CA TAP1 PYCARD CD4 SUPT4H1 MSH6 CR2 MSH3 MSH2 CEBPG CENPF BIRC5 TBX1 SMC2 SMC3 NAE1 CD1D SMC4 VWF SP1 GLA BAX BNIP3L TRPC4AP PPP2R4 HPGD BARD1 | |
| CHANNEL_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CHANNEL_REGULATOR_ACTIVITY SRI SGK2 KCNAB3 KCNAB2 KCNAB1 NPY2R ARPP19 ENSA TNNI3 KCNJ12 KCNMB1 TMPRSS3 KCNV1 KCNMB2 KCNS3 KCNS1 NPY ADRA2A KCNE1 CHRNA7 NEDD4L CHP PDZD3 RSC1A1 | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS SIRT4 UPP1 SIRT5 UPP2 SIRT6 QTRT1 HPRT1 PNP SIRT1 ART1 PPAT SIRT3 APRT ART3 TYMP UMPS XYLT1 QPRT TNKS PARP1 | |
| SIGNAL_SEQUENCE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SIGNAL_SEQUENCE_BINDING KDELR2 NFKBIA SSR1 PEX7 BRE KPNA3 TNPO2 KPNA2 KDELR1 KPNB1 TNPO1 KPNA1 SSR2 SSR3 TOMM34 | |
| MONOVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MONOVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY ATP6V0E1 SLC9A7 COX11 UQCRC1 SLC9A6 SLC9A5 COX10 SLC9A3 SLC9A2 COX7B KCNA1 COX7A2L ATP6V1B2 COX5A COX5B ATP6V0C COX15 SLC8A1 COX7A1 ATP4A ATP4B ABCB11 COX8A COX4I2 COX4I1 CYB5A TRAPPC10 ATP6V1C1 ACCN4 NNT UQCRH SLC13A4 ABCC8 SURF1 | |
| STRUCTURAL_CONSTITUENT_OF_MUSCLE http://www.broadinstitute.org/gsea/msigdb/cards/STRUCTURAL_CONSTITUENT_OF_MUSCLE MYL6 MYL5 TCAP MYBPC2 MYL2 MYBPC1 MYL3 MYBPC3 TPM2 PLEC TTN TPM1 MYOT TPM4 MYL9 MYOM2 MYL6B SORBS2 DMD MYBPH MYOM1 ASPH ACTC1 MYLPF MYH7 ACTN2 ACTN3 MYH6 NEBL KRT19 SMTN NEB MYH11 | |
| L_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/L_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC38A3 SLC7A10 SLC7A9 SLC3A1 SLC7A11 SLC25A12 SLC1A2 SLC25A13 SLC1A3 SERINC1 SLC1A6 SLC1A7 SLC25A22 CTNS SLC1A1 SLC25A15 OCA2 | |
| PROTEIN_PHOSPHATASE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_PHOSPHATASE_BINDING LILRB1 PPME1 SMG5 BCAR1 PPP6R3 SMG7 PPP2R4 AKAP11 SOD1 PIK3R1 | |
| OXIDOREDUCTASE_ACTIVITY_ACTING_ON_CH_OH_GROUP_OF_DONORS http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_ACTING_ON_CH_OH_GROUP_OF_DONORS LDHC LDHB D2HGDH LDHA EHHADH ADH1B HSD3BP4 AKR1C3 RDH8 IDH3G AKR1C4 MIOX AKR7A2 AKR7A3 SPR HADH IMPDH1 IMPDH2 AKR1C1 DHRS9 GRHPR CBR3 RDH5 HAO1 DHRS2 H6PD AKR1B10 HAO2 MDH1 HSD3B2 ME1 HSD17B10 ME3 HSD3B1 ME2 HSD17B14 UGDH ADH6 ADH7 HADHA ALDH3A1 HADHB CBR1 AKR1A1 ADH4 IDH1 BDH2 HSD17B4 TSTA3 BDH1 HSD17B7 NSDHL GPD2 GPD1 tAKR IDH3B RDH12 RDH11 RDH10 L2HGDH AKR1B1 PHGDH RDH16 HPGD | |
| COENZYME_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/COENZYME_BINDING ME1 NOX4 HACL1 ALDH6A1 GCLC AIFM2 PPOX GRHPR MTRR NDOR1 ACOT7 NNT SPR BDH2 HPGD WWOX | |
| GTPASE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/GTPASE_BINDING FGD2 ALS2 FGD1 RAB3GAP1 RTKN ABCA1 CDC42EP2 RANBP9 DMXL2 IPO5 RAPGEF6 RANBP3 RANBP1 RANBP2 GOLGA5 FGD5 FGD6 RASA1 FGD4 CDC42EP5 PARD6A RILP ARHGEF2 RALBP1 ARFIP2 IPO9 IPO8 DOCK4 PLCE1 IPO7 SGSM3 CYFIP1 GGA2 GGA3 | |
| GROWTH_FACTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/GROWTH_FACTOR_BINDING A2M IL1R1 ACVRL1 IL9R HAX1 IL6ST IL7R IGF1R ACVR1B CEP57 IL10RB INS CTGF IL10RA IL4R CSF2RB IL2RG API5 IL2RB IL2RA TGFBR1 IGFALS NRD1 IL6R NTRK3 ACVR2B NTRK1 NTRK2 IGFBP1 IL5RA IL3RA ACVR1 | |
| ENZYME_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ENZYME_BINDING ALS2 A2M VAPB PDLIM5 RAB3GAP1 FOXO3 UBQLN1 FOXO4 CDKN2A ANK1 DMXL2 CDKN2B PACSIN3 CDKN2C CDKN2D APOA5 SERPINE1 RAPGEF6 SUPT5H MAP2K7 INSR FIZ1 S100A1 KIF13B ADAM9 CUTA BCL10 MAGI2 ZC3HC1 DFFB RELA PICK1 SOCS1 PTPRR HDAC10 RAD9A CD40 IRS1 PLAUR LILRB1 PLCE1 HIF1A NPC2 SGSM3 PPP6R3 AKAP5 ABAT AKAP7 ATPIF1 KAT2A AKAP3 SUDS3 AKAP4 FGD2 FGD1 EID1 PPME1 ADAMTSL4 AKAP12 APOC2 NFKBIA ITGB2 AKAP11 ABCA1 GCLM LLGL1 CDC42EP2 DNMT3L HAUS7 BCOR FGD5 FGD6 CDC42EP5 FGD4 PARD6A RILP EPAS1 SMG5 SMG7 AKAP8L MOB1B ARFIP2 TREX2 UBE2L3 ATG3 CAMK2N1 BRCA1 DOCK4 HDAC2 HDAC1 AVPR1B AVPR1A CYFIP1 GRK5 PARP4 TRIP6 HDAC6 PREX1 BCAR1 HINT1 PAWR PRDX3 LATS1 RANBP9 NOD2 CEP250 MAPT SERPINA5 IPO5 RANBP3 RANBP1 CDK5RAP2 RANBP2 TOP2B GOLGA5 CASP2 TOP2A DHCR24 DLG1 IRAK1 ARHGEF2 SIT1 CCDC88A ADAM10 NOS1AP ZP2 RALBP1 ZP3 ZP4 TP53 IPO9 RB1 TOPORS IL6R IPO8 PRKCD NLRP1 SPDYC SPDYA MAST2 CCND3 LAX1 IPO7 LCK MDM2 MAP3K13 MAP3K12 CSF3 TRIB3 RTKN IGF1R SQSTM1 BCL2 CD4 CD24 TPRKB RASA1 PIK3R1 APC PTPRC ZBTB7A UBE4B COTL1 SOD1 YWHAE SIRT2 SELS VWF YWHAG RPS6KA4 MAPK8IP2 MAPK8IP3 KAT2B PPP2R4 FAF1 MAPK8IP1 GGA2 GGA3 | |
| CHROMATIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CHROMATIN_BINDING PAM ING2 EZH1 POLA1 CBX3 CBX1 RCC1 TOP1 ERCC6 CENPA ACTL6A BCL6 TOP2B CDCA5 TOP2A UPF1 RAN POLE TP53 SUV39H1 APTX KLHDC3 SMARCE1 POLD1 NCOA6 FOXC2 MPO CHAF1A VCX SMC1A CHAF1B NSD1 | |
| LIPID_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/LIPID_TRANSPORTER_ACTIVITY CDIPT PITPNA SFTPA1 ABCA1 SLCO2A1 APOA4 APOA1 CFHR4 APOD APOC4 APOF ATP8B1 PITPNC1 CETP HSD17B4 APOM PCTP ATP11B GLTP ABCG1 PLSCR1 PITPNM1 APOL3 NPC1 LRP1 PITPNM3 APOL1 SLC27A4 | |
| PURINE_RIBONUCLEOTIDE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PURINE_RIBONUCLEOTIDE_BINDING BTK MAP3K6 MAP3K5 DHX38 WNK4 VPS4A TLK1 TLK2 RAB26 EIF2B2 GTPBP1 GTPBP4 GTPBP6 RAN ABCB11 NCF1 PIM1 WNK1 OLA1 WNK3 WNK2 GEM MYH9 SARS2 MARK1 MARK2 RND3 RFC1 NME1 RFC2 ARL8A ARL8B NEK6 STK17B MYO9B ARF6 PXK STK17A TGFBR1 NIM1 SPHK1 ARFIP2 OXSR1 ABCG1 ABCG2 RERG CDC42BPG ARF3 CDC42BPA RHEB TNK1 RIT1 RIT2 CDC42BPB ABCF1 BCKDK SEPHS1 ACVRL1 ABCF2 NUAK2 LATS1 LATS2 NMUR2 SIK3 RAP2B SRPK2 ACTA1 ARHGEF5 TPX2 TP53 CFTR SRPK1 RAD51 EIF4A3 MAST1 SIK2 MAST2 MKNK2 MKNK1 GALK1 DGKE SNRK ABCD2 ABCD4 PDS5B NLK TRIM23 APRT RPS6KA5 RPS6KA4 RAB22A ABCC3 HSPA4L DGKZ ABCC1 PPP2R4 PGK1 ABCC8 ABCC5 ABCC6 PGK2 SIK1 ZAK STK38 STK36 HBS1L TTN DMPK NLRC4 DDX25 CLP1 RALB RALA PRKACB MX1 GNL1 GNL3 TWF2 MYO6 MYO3A STK4 CDKL5 STK3 MAP4K3 NVL MAP4K4 MAP4K5 SMARCA5 SEPT6 SEPT7 GBP2 GBP1 ME1 ABCA7 GCLC STK11 MAP4K2 RRAGA MAP4K1 ABCA2 ABCA4 ABCA3 RRAGB RRAGC IRAK3 DYRK3 DYRK2 STK38L EEF1A1 GABARAPL2 ABCB8 EPB42 PIF1 ABCB1 ABCB7 ABCB6 TRNT1 ATP7A ABL1 ATP7B MYH10 PC PEX6 PINK1 MOV10L1 ACVR1B PEX1 RHOB RHOH HSP90AA1 PRKCI MINK1 DAPK2 DAPK3 NEK11 NLRP1 DAPK1 ARL3 ERN1 ERN2 DMC1 ACVR1 BRSK2 TRIB1 N4BP2 ERCC6 CDK11A CDK11B TOR1A TGM3 SCG5 MSH6 MSH2 DRG2 GSG2 SMC4 ICK GCK TSSK1A TSSK2 BMPR1B TSSK4 TSSK3 TSSK6 BMPR1A | |
| AMINE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/AMINE_BINDING GLRB GCLC GLRA1 GLRA2 ADRB3 CHRM5 ADRB2 ANXA9 CHRM4 CHRM3 CHRM2 CHRM1 CHRNB4 CHRNA5 CHRNA4 CHRNB2 CHRNA7 CHRNB1 CHRNA6 CHRNA1 CHRNE CHRNA3 CHRNA2 | |
| ORGANIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ORGANIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC38A3 AQP9 SLC22A12 SLC7A8 SLC7A9 SLC7A4 SLC7A5 SLC7A6 SLC1A4 SLC1A5 SLC1A2 SLC16A1 AKR1C4 SLC1A3 SLC1A6 SERINC1 SLC25A22 SLC1A7 SLC25A1 SLC43A1 SLC1A1 OCA2 PDPN ABCB11 SLC6A14 SLC7A10 SLC3A1 SLC10A2 SLC7A11 SLC10A1 SLC25A12 SLC16A2 SLC6A9 SLC16A4 SLC25A13 SLC16A7 SLC16A6 SLC7A2 SLC6A5 SLC25A10 SLC16A8 SLC6A6 SLC13A2 CTNS SLC25A15 | |
| UNFOLDED_PROTEIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/UNFOLDED_PROTEIN_BINDING PTGES3 GRPEL1 SPG7 RP2 CCT3 HSPA1B LMAN1 NAP1L4 CDC37 AIP TAPBP TTC1 UGGT1 CCT6B HSPA2 NPM1 TOR1A TOR1B MKKS SCG5 DNAJA3 HSPA9 CLN3 AIPL1 TCP1 APCS CCT6A AFG3L2 LRPAP1 CCT7 CLGN CCT4 PPIB PPIA PPIC TOMM20 DNAJB2 RUVBL2 HSPD1 CHAF1A DNAJB4 CHAF1B | |
| TRANSITION_METAL_ION_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/TRANSITION_METAL_ION_BINDING GDA APOBEC1 ATOX1 MMP9 MMP8 ADH1B APOBEC3G MMP2 APOBEC3F MMP1 APOA4 ZNF185 TIMM9 ERAP2 LOX FECH CIZ1 CA12 YY1 HDAC10 PIM1 TIMM8B ISCU PRDM4 SLU7 PIAS2 MYNN ME1 FDX1 DUSP12 MYT2 ARIH2 RPS27 ECE2 RPS29 CDA RNF11 ADAM30 DYRK2 KLF7 CRIP1 RABIF CRIP2 CSRP1 BRCA1 S100A12 ATP7A CBLC CBLB RNF7 S100B RNF4 RNF5 TRPS1 PHEX ABL1 ABL2 ATP7B SEPX1 CTCF ZEB1 GLI2 LNPEP TYR MMP20 ANG ZNF146 KPNB1 MT3 ACO2 TP53 MMP17 MMP16 MMP15 MMP14 MMP13 MMP12 MMP10 CHMP1A MDM2 ZFPM2 SIAH1 CA2 PPM1M MDM4 PRNP AOC3 ADAMTS13 POLR2K POLR2I TIMM10 EEA1 TIMM13 DCT CD4 CCS LIMD1 PEX12 CHD4 SIRT6 BIRC5 SOD1 ZNF22 MSRB2 SIRT2 MSRB3 RLF MNAT1 RASSF1 MEP1B LTA4H | |
| OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORSNAD_OR_NADP_AS_ACCEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORSNAD_OR_NADP_AS_ACCEPTOR ALDH8A1 ALDH6A1 ALDH5A1 ADH5 ALDH3B2 ALDH3A2 ALDH3B1 ALDH3A1 GAPDHS ALDH1A1 ALDH1A2 ALDH7A1 ALDH1A3 ALDH2 ALDH4A1 ALDH9A1 | |
| SH3_SH2_ADAPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SH3_SH2_ADAPTOR_ACTIVITY SNX9 GRAP GRB2 RUSC1 FCRL2 ABI2 ITSN2 SKAP2 SKAP1 SRC SLA ARHGAP4 SHB ARHGAP6 ARHGAP1 GAB1 SH3BGR STAM SH2B2 CNTNAP1 BLNK KHDRBS1 IRS4 VAV3 SOCS2 TP53BP2 SLA2 SH3BGRL LAT SH2D2A SH2D3C GRB10 CRKL SH2D3A EPS8 LASP1 CHN1 CHN2 GRAP2 GRB7 GRB14 SH3BP2 TOB1 | |
| SMALL_CONJUGATING_PROTEIN_LIGASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SMALL_CONJUGATING_PROTEIN_LIGASE_ACTIVITY DZIP3 RNF217 MYLIP WWP2 WWP1 FBXO22 ANAPC2 ANAPC5 ANAPC4 UBR3 UBE2H UBE2C BRAP UHRF2 HUWE1 UBE2K UBR5 UBE2M DDB2 MDM2 FBXL6 AMFR ZER1 FBXL2 ANAPC10 UBE3C ANAPC11 STUB1 ERCC8 ARIH1 UBE2D3 UBE2D2 FBXW2 TRAF7 FBXO3 TRAF6 RNF14 FBXO7 RNF144B FBXO2 CBL UBE2L6 CDC23 MALT1 PARK2 TRIM23 BIRC3 UBE2L3 SMURF2 SMURF1 UBE2E1 | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_SULFUR_CONTAINING_GROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_SULFUR_CONTAINING_GROUPS GAL3ST2 TPST1 TPST2 HS3ST6 HS3ST5 NFS1 SULT2B1 CHST10 OXCT1 CHST12 CHST11 CHST14 CHST13 SULT1C2 HS6ST1 SULT1E1 SULT1A4 GAL3ST1 UST CHST2 CHST3 CHST4 CHST5 CHST1 TST CHST7 CHST6 CHST9 CHST8 CHST15 HS3ST3B1 MPST | |
| GLYCOSAMINOGLYCAN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/GLYCOSAMINOGLYCAN_BINDING HDGF FGF10 FSTL1 POSTN PF4 MDK ANG SERPINA5 IMPG2 APOA5 ZNF146 ACAN ODZ1 FGFBP1 THBS2 THBS4 LPL TNXB COL13A1 CHODL COL25A1 STAB2 RPL29 LRPAP1 TNFAIP6 PODXL2 LAYN VEGFA AAMP HBEGF TGFBR3 VCAN EPYC HABP2 | |
| PHOSPHATASE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHATASE_BINDING PPME1 MAGI2 SMG5 BCAR1 SMG7 AKAP11 SOD1 LILRB1 MAST2 PPP6R3 PPP2R4 PIK3R1 DLG1 | |
| CARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC38A3 AQP9 SLC7A8 SLC7A9 SLC7A4 SLC7A5 SLC7A6 SLC1A4 SLC1A5 SLC16A1 SLC1A2 AKR1C4 SLC1A3 SLC1A6 SERINC1 SLC25A22 SLC1A7 SLC25A1 SLC1A1 SLC43A1 OCA2 ABCB11 PDPN SLC6A14 SLC7A10 SLC3A1 SLC10A2 SLC7A11 SLC10A1 SLC25A12 SLC16A2 SLC6A9 SLC25A13 SLC16A4 SLC16A7 SLC16A6 SLC7A2 SLC25A10 SLC6A5 SLC6A6 SLC16A8 SLC13A2 CTNS SLC25A15 | |
| NICOTINIC_ACETYLCHOLINE_ACTIVATED_CATION_SELECTIVE_CHANNEL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NICOTINIC_ACETYLCHOLINE_ACTIVATED_CATION_SELECTIVE_CHANNEL_ACTIVITY CHRNB4 CHRNB3 CHRNA4 CHRNB2 CHRND CHRNA7 CHRNA6 CHRNA1 CHRNE CHRNA3 CHRNA2 | |
| PHOSPHATASE_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHATASE_REGULATOR_ACTIVITY PPP2R3B PPP2R3A PPME1 PPP2R5B PPP2R5A PPP2R5D SET PPP1R1B PPP1R1A LMTK2 PTN PPP2R2B FRS2 PPP2R1A TESC ANP32E SAG PPP1R2 PPP1R7 PPP1R8 IGBP1 PPP2R4 PPP2R5E EIF2AK2 IGFBP3 PPP2R2A | |
| CALMODULIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CALMODULIN_BINDING IQCB1 MYO7A CALD1 MYO9B TTN IQGAP1 CAMKK2 TRPV4 TRPV6 MYO6 MYO3A STRN4 SPHK1 DAPK2 RGS16 DAPK1 RGS1 RGS2 RGS4 RIT1 ATPIF1 MARCKS RIT2 NRGN CACNA1C | |
| GLUTATHIONE_TRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GLUTATHIONE_TRANSFERASE_ACTIVITY GSTA2 GSTA3 GSTA4 GSTT1 GSTT2 LTC4S GSTM5 GSTM1 MGST3 GSTM2 GSTM3 GSTM4 GSTZ1 MGST1 MGST2 | |
| TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSMEMBRANE_TRANSPORTER_ACTIVITY ATP1B1 SLC9A7 SLC9A6 AQP9 ATP1B3 SLC9A5 ATP1B2 AQP8 SLC9A3 SLC9A2 AQP5 AQP7 AQP6 SLC35A1 SLC35A2 SLC35A3 AQP2 ATP2B1 CUL5 ATP2B3 ATP2B4 KCNK7 KCNK6 KCNK5 CHRNA4 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 SLC12A7 CLCA2 SLC12A9 CLCA1 CLCA4 SCN2B ABCB11 PDPN SCN2A TRPA1 NNT ADAMTS8 RHCG PPBP ATP2C1 RYR3 RYR1 RYR2 SURF1 KCNMB3 CLCN1 ORAI1 KCNMB4 CLCN3 SCN1B CLCN2 CACNB1 CACNB2 CACNB3 CACNB4 KCNJ3 KCNMB1 KCNMB2 KCNJ1 SLC29A1 SLC11A2 ATP6V0C SLC29A2 SERINC1 SLC31A2 SLC28A2 SLC31A1 TRPC1 TRPC4 TRPC3 TRPC5 ATP11B KCNK1 KCNK3 ABCG1 KCNK4 ABCG2 KCNJ5 KCNJ4 KCNJ6 ATP2A2 LASP1 ATP2A3 ATP2A1 CHRNB4 CHRNB3 CHRNB2 CHRND CHRNB1 CHRNE P2RX6 CLCN4 CHRNG SLC9A1 ABCF1 KCNH1 GJA8 KCNK17 KCNJ15 COX11 KCNK15 ATP6V0E1 GLRA1 SLC20A1 SLC15A1 TRPV1 SLC20A2 COX10 SLC15A2 TRPV2 GLRA2 GJA1 KCNJ10 KCNIP2 HVCN1 KCNJ12 KCNJ14 KCNK10 SLC23A1 FXN SLC23A2 NMUR2 SLC22A4 TRPV5 SLC25A3 SLC22A3 SLC22A6 SLC25A1 TRPV6 SLC22A2 COX15 KCNG2 SLC22A1 SLC25A4 ATP4A SLC25A5 ATP4B SLC22A7 SLC22A8 CACNG5 SLC3A2 CACNG4 CFTR CYB5A CACNG2 SLC3A1 CACNG1 STX1B ATP6V1C1 SLC26A4 KCNA10 BSND SCN11A KCNH2 STEAP1 KCNH3 KCNH4 CLDN16 SHROOM2 COX7A2L SLC19A2 BEST1 KCNE1 PKD2 KCNE2 ABCD3 ABCD4 HTR3A HTR3B SLC8A1 COX7A1 ATP1A3 ATP1A4 ATP1A1 ATP1A2 ITPR3 ITPR1 TRAPPC10 ITPR2 ACCN1 SLC16A2 ACCN4 SLC16A4 SLC16A7 SLC16A6 SLC16A8 ABCC3 ABCC1 ABCC2 CTNS ABCC8 ABCC5 ABCC6 KCNC1 KCNC4 SLC44A1 SLC44A2 KCNC3 SLC22A13 SLC22A12 SLC6A2 SLC6A3 SLC6A4 SLC22A14 SLC7A8 SLC7A9 SLC22A11 CNGB1 SLC7A4 COX5A COX5B SLC7A5 SLC7A6 TAPBP SLC2A8 SLC16A1 SLC2A5 SLC2A4 SLC2A3 SLC2A2 SLC25A22 SLC2A1 MS4A2 SLC4A2 SLC4A1 SLC4A4 SLC4A3 KCND3 SLC34A1 CNGA3 SLC34A3 SLC34A2 SEC61B SLC40A1 ABCA8 FXYD1 FXYD2 SLC38A3 FXYD3 MCL1 KCNA2 COX7B KCNA1 KCNA4 KCNA3 KCNA6 ATP6V1B2 KCNA5 ABCA3 KCNS3 KCNS1 GAR1 ZACN SCN9A SLC30A4 SLC30A5 SLC30A3 CACNA2D1 KCNB2 COX8A SLC6A14 ABCB7 CACNA1S ANKH ATP7A P2RX5 SLC25A12 SLC25A11 P2RX4 P2RX7 SLC25A13 SLC4A11 P2RX1 SLC7A2 SLC25A10 P2RX3 P2RX2 CACNA1G SLC13A2 CACNA1H SLC25A19 CACNA1E CACNA1F SLC13A4 CACNA1C ASNA1 SLC25A15 CACNA1D CACNA1A CACNA1B ATP7B SLC5A3 SLC5A2 SLC5A5 UQCRC1 SLC5A1 SLC1A4 SLC1A5 KCNQ5 SLC1A2 AKR1C4 SLC1A3 KCNQ3 CCT8L2 SLC1A6 SLC1A7 ATP8B1 SCN7A KCNQ2 SLC1A1 SLC43A1 KCNQ1 OCA2 TRPM5 COX4I2 SLC7A10 COX4I1 SLC7A11 TRPM2 TRPM1 UQCRH SLC37A4 CLCNKA CLCNKB SLC35B1 SLCO1A2 SLC35B2 SLC35B4 CCS SCNN1G SCNN1B SCN5A SCNN1D SLC39A2 PLP2 GLRB NOX5 SLC12A1 SLC12A2 SLC12A3 SLC12A4 NOX1 MAL SLC10A2 RHAG SLC10A1 SLC17A7 KCNN4 SLCO1B3 SLC6A9 SLC17A5 SLC17A3 SLC17A4 SLC6A8 SLC17A1 SLC6A5 KCNN3 SLC6A6 SLCO1B1 SLC17A2 KCNN2 SLC18A2 SCN4B SLC18A3 SLC5A6 SLC18A1 SLC5A7 SLC14A1 SCN4A SLC14A2 | |
| PYROPHOSPHATASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PYROPHOSPHATASE_ACTIVITY XRCC5 FHIT ATP1B1 ATP1B3 ATP1B2 XRCC6 RAB1A ATP2B1 ATP2B3 DDX17 ATP2B4 DDX18 DHX38 DIRAS3 RAB28 VPS4B GNG3 RAB27B RAB27A GTPBP2 GTPBP4 OPA1 RAN NCF1 ABCB11 EIF2S3 MYH7 NUDT10 NUDT11 MYH6 MYH9 RND2 RND3 RFC3 ATP2C1 SMARCAL1 AGAP2 RAB13 GNAI3 GNAI2 ENPP1 GNAI1 ENPP2 ENPP3 ARF6 MYO9B ARF5 ATP6V0C THTPA RAC2 RAC3 RAC1 DHX8 DHX9 ATP11B RAB7L1 ABCG1 PPA1 ABCG2 RERG GNGT1 ARF1 ATP2A2 ATP2A3 ARF3 ATP2A1 CCT8 ARF4 RHEB RAD54B GNAZ ABCF1 ATP6V0E1 RAB5B RAB5C RAB6A TOP2A RAP2A RBBP4 ATP4A ATP4B RAB4A TTF2 RAD51 ATP6V1C1 GNAL EIF4A3 GNAQ GNB2 GNB1 RAB5A RUVBL2 GNAS RUVBL1 GNB3 ARL4D DOLPP1 RASD1 ARL4C ARL4A RAB3A RAB3B RAB3D WRNIP1 SKIV2L GNG11 INO80 RAB11B ABCD3 ABCD4 RAB2A UPF1 ATP1A3 ATP1A4 ATP1A1 ATP1A2 TRIM23 RAB31 RAB30 RAB35 GNG10 RAB22A ABCC3 KIF20B PPP2R4 ABCC1 ABCC2 DNM1 ABCC6 SEPT5 GNA13 SEPT4 GNA14 GNA15 RAB9A GNA11 SNRNP200 GNA12 EIF5 RRAD TAPBP DDX23 DDX25 RRAS DDX21 DDX20 MX2 NUDT2 NUDT1 MYO3A NUDT4 NUDT3 EFTUD2 NUDT5 PICK1 CLPX SMARCA5 SMARCA1 SEPT9 DDX39A MYL6 ABCA8 RAB7A FXYD2 MRAS ARFRP1 KATNB1 ABCA2 ATP6V1B2 ABCA3 RRAGC DDX3X KATNA1 ENTPD4 RAB6C DDX43 PIF1 MYO1E ABCB7 RAB33A ATP7A DDX56 PSMC6 PSMC5 VCP PSMC4 PSMC1 RAP1A DDX54 MYH10 DUT ATP7B RSF1 PEX6 CDC42 ARHGAP5 PEX1 RASL10A ATP8B1 RHOA RHOB RHOC RHOD RHOG ARL1 RALBP1 G3BP1 RECQL KIF1B BPTF RRAS2 ERCC8 ERCC6 CHD2 CHD1 TGM3 ERCC3 CHD4 CHD3 MSH6 DNM1L GNAO1 MSH2 RABL2A RABL2B GSPT1 | |
| THYROID_HORMONE_RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/THYROID_HORMONE_RECEPTOR_BINDING MED12 MED24 MED14 MED13 MED4 OASL MED30 NUP62 MED16 MED17 NCOA6 THRAP3 JMJD1C NSD1 TRIP12 ZNHIT3 MED1 | |
| CYTOKINE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/CYTOKINE_BINDING A2M IL9R ACVRL1 IL6ST IL4R IL15RA CSF2RB XCR1 IFNGR2 IFNGR1 EBI3 IL13RA2 CMKLR1 TNFRSF14 IL6R IFNAR1 IFNAR2 IL18BP IL12A GPR17 ACVR1 IL1R1 IL22RA1 HAX1 TNFRSF25 CRLF1 CNTFR IL7R TNFRSF4 CD74 IL12RB2 TNFRSF1A TNFRSF1B IL12RB1 IL10RB IL10RA IL17F TNFRSF18 IL2RG PLP2 IL2RB IL2RA TGFBR1 CXCR2 IL5RA ELANE IL3RA IL22RA2 | |
| HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_NOT_PEPTIDEBONDSIN_LINEAR_AMIDES http://www.broadinstitute.org/gsea/msigdb/cards/HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_NOT_PEPTIDEBONDSIN_LINEAR_AMIDES AGA ACR ACY1 PDF DARS UPB1 HDAC10 HDAC11 HDAC7 SIRT2 HDAC5 GLS2 HDAC3 ASPA HDAC2 HDAC1 PGLYRP2 FAAH ASRGL1 HDAC8 HDAC6 | |
| SERINE_TYPE_ENDOPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SERINE_TYPE_ENDOPEPTIDASE_ACTIVITY ACR PREP MASP1 CELA3A CORIN MASP2 PRSS1 C1R C1S PCSK2 HTRA2 HTRA1 KLKB1 PRSS2 PRSS3 TOR1A PCSK9 LTF CFI PRSS36 PCSK6 CFD HGFAC F11 F12 KLK8 F10 CELA2B KLK2 GZMA F9 GZMB KLK1 F7 FURIN TMPRSS6 PLG PROC APEH F2 CTSG | |
| TRANSLATION_INITIATION_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSLATION_INITIATION_FACTOR_ACTIVITY EIF2C1 COPS5 EIF5A EIF2S3 EIF2A EIF2B1 EIF3C EIF4G1 EIF4B EIF4G2 EIF3D EIF3B EIF4E EIF4A2 EIF2S1 EIF3E EIF4H EIF3F EIF2S2 EIF3J EIF2B2 EIF2B3 EIF2B4 EIF2B5 | |
| TRANSITION_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSITION_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC11A2 FXN SLC30A4 SLC30A5 CCS SLC30A3 SLC31A2 SLC31A1 SLC40A1 SLC39A2 | |
| NUCLEASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/NUCLEASE_ACTIVITY RPP38 DICER1 RNASEH1 DNASE1L2 DNASE1L3 DNASE1L1 ISG20 ANG RNASE7 RNASE8 DBR1 RPP30 DFFA EXOSC7 PGAP1 DFFB TP53 EXOSC2 APTX RAD9A MBD4 RNASEH2A RAD50 RAD1 NME1 ERN2 XRN2 ENPP2 ENPP3 MRE11A N4BP2 ERCC5 REXO2 APEX1 ERCC4 NTHL1 ERCC1 FEN1 EXO1 RNASE1 RNASE2 RNASE3 RNASE6 TREX2 TREX1 WRN DNASE2 PPP1R8 MAP1S POP1 POP4 OGG1 POP7 RPP40 ERI1 | |
| SECRETIN_LIKE_RECEPTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/SECRETIN_LIKE_RECEPTOR_ACTIVITY CRHR1 CRHR2 TAPT1 PTH2R BAI1 BAI2 PTH1R VIPR1 GHSR GCGR SCTR | |
| RIBONUCLEOPROTEIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/RIBONUCLEOPROTEIN_BINDING PRPF31 NAA15 NAA16 SRPR TIMM50 EIF2A MTIF2 RPS21 ETF1 MTIF3 SRP9 NAA10 | |
| ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES http://www.broadinstitute.org/gsea/msigdb/cards/ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES ABCA8 ABCF1 FXYD2 ATP1B1 ATP6V0E1 ATP1B3 ATP1B2 ATP6V1B2 ABCA3 TAPBP ATP2B1 ATP6V0C ATP2B3 ATP2B4 ATP8B1 ABCD3 ABCD4 ATP4A RALBP1 ABCB11 ATP4B ATP11B ATP1A3 ATP1A4 ATP1A1 ATP1A2 ABCB7 ABCG1 ABCG2 ATP7A ATP6V1C1 ATP2A2 ATP2C1 ATP2A3 ATP2A1 ABCC3 ABCC1 ABCC2 ABCC6 ATP7B | |
| GENERAL_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GENERAL_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY TAF1C TAF1A CNOT2 MED24 TBP MED20 GTF2A1 MED26 TAF9 TCEA1 TAF4 TAF6 TAF7 MED12 MED14 MED13 PPARGC1A GTF2B PPARGC1B GTF2H1 TAF11 MED4 TAF13 TAF12 MED30 GTF2I ABT1 MED17 GTF2F1 THRAP3 GTF2F2 MED1 | |
| TRANSFERASE_ACTIVITY_TRANSFERRING_GROUPS_OTHER_THAN_AMINO_ACYL_GROUPS http://www.broadinstitute.org/gsea/msigdb/cards/TRANSFERASE_ACTIVITY_TRANSFERRING_GROUPS_OTHER_THAN_AMINO_ACYL_GROUPS SAT1 CERS5 ALAS2 NAA16 GNPAT KAT7 KAT8 KAT6B AGPAT2 KAT6A TAF1L ELP4 SPTLC1 SPTLC2 PNPLA3 ZDHHC17 EP300 LRAT DGAT1 DGAT2 NCOA3 SMARCE1 EDF1 SRCAP CROT HAT1 ACAT1 HADHA HADHB LPCAT1 AANAT ACSL3 GTF3C4 SOAT1 SOAT2 CPT1B TAF1 TAF5 NAT1 NAT2 CREBBP MCAT BRCA2 CPT1A OXSM GLYAT NAA15 CERS1 YKT6 | |
| DNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/DNA_BINDING XRCC5 XRCC4 SLC2A4RG SURF6 XRCC6 RORB ZNF638 MXI1 CITED2 TAF5L FLI1 FOXF1 FOXF2 PQBP1 PHTF1 ZNF395 FOXS1 ZNF43 PHOX2B IKBKAP ZNF45 KDM5B RXRA LIG1 KDM5A ZHX1 MECP2 LIG3 ZHX2 ZHX3 LIG4 LHFP HNF4G ORC1 NME2 ZNF238 HNF4A JUN FOXG1 ZNF239 TGIF1 SHOX RAD23B ZNF132 ZNF133 RAD23A MYEF2 MYBL2 FOXH1 LYL1 ZNF124 TCF4 NTHL1 TCF3 DMBX1 YEATS4 DNMT3A KLF12 KLF10 SPHK1 KLF11 TFCP2 GAS7 USF2 ZNF217 TRPS1 PARP4 PARP1 FOXI1 ZNF219 BACH1 HLF HNF1B ELF1 LZTS1 HNF1A TSG101 FOXA3 EZH2 ZNF155 SPI1 YBX1 ZNF350 HSF1 HSF2 ZNF146 SERPINA3 HSF4 MYC BATF3 AR MTERF AIFM2 PTF1A ZNF142 GTF2H4 TP53 MXD1 ZNF140 MYCN PFDN1 TAF13 ZNF137P FOXC2 FOXC1 CLOCK ZNF274 MECOM ZBTB6 SCML2 SCML1 POLA1 ABI2 ZNF367 ZNF35 SPO11 INO80 POT1 ZNF175 ZNF174 TADA2A GBX2 SUPT4H1 FOXD2 FOXD1 SIM1 FEN1 FOXD4 FOXD3 SIM2 ZNF263 MYF6 SSRP1 LZTR1 LMX1B TRIM29 MYF5 TRIM28 TRIM26 TNP1 TRIM25 TRIM22 TP73 ZNF22 RLF ZNF157 TADA3 PPBPL2 BNC1 FOXE1 PHF5A OGG1 NR5A2 ZNF256 FOXE3 REPIN1 LMO1 LMO4 RBM5 RBM6 ZIC1 CNOT7 CBFB BATF IGHMBP2 PMS2 PMS1 MCM3AP RELA RELB HNRNPA2B1 GABPA ZNF7 ARID1A HES6 ARID1B CSDA HNRNPU HHEX PA2G4 EP300 HIF1A TCFL5 TFAP2B SMARCA5 EDF1 NFE2L1 NFE2L2 TFAP2C NFE2L3 SMARCA4 HMGB1 HMGB2 CNBP CCRN4L HMGB3 SYCP1 NR2C2 ATF1 CXXC1 ARNT RPL6 TFEC TRAF4 TFDP1 EPAS1 SMG6 TAF5 FOXA1 NEUROG1 VAV1 DNASE2 ATF6 ATF4 ATF3 HDAC2 HDAC1 POLD1 TDG HIVEP2 HIVEP1 E2F1 E2F3 SOLH FOSL2 CELF3 E2F4 ARID4A DEDD PAX6 ZNF202 CTCF PAX3 PAX2 FEV MAX KIF2C ORC4 HEY1 PAX7 PAX8 HEY2 E4F1 NFIL3 FOSL1 LBR RBPJL NFX1 ARID5B DDB1 KIF15 ZFX ARID5A CDK9 IFI16 RB1 ESR2 TOPORS HMGA2 HLTF HMGA1 PURB PURA CDK2AP1 DDB2 ORC5 DMC1 BCLAF1 RAG1 NR3C2 NFYC NFYB WBP11 NR3C1 NFYA HIC1 TFAM TSC22D3 ORC2 CEBPZ GTF3C6 CHD2 NFATC2 GTF3C2 TERF2 CHD4 NFATC1 CHD3 TERF1 EXO1 CREB1 CEBPG CBL CREB5 RCAN1 ORC3 ZRANB2 ALKBH3 ALKBH2 SCAND1 HMGN1 RAD51C CDX2 STAT5A MORF4 STAT5B HIRA PTTG1 DNASE1L2 DNASE1L3 DNASE1L1 CRY1 PITX2 POLH NKX2-6 YY1 POLE TAF6L TBR1 PPARGC1A HES1 PNKP RFC3 UHRF1 HUWE1 MTF1 MNT PRDM1 SUPT6H LENEP TFCP2L1 MRE11A FIGLA MYT2 TAL2 PLAGL1 TAL1 DRAP1 SUPV3L1 LHX6 MAML3 WDHD1 POLQ NKX2-5 TCF25 NR1H4 PLAGL2 PLAG1 IKZF4 ZBTB48 KLF7 IKZF3 IKZF1 KLF9 SUB1 CREBBP SMAD4 TREX1 SMAD3 SMAD2 UBP1 HNRNPA1 DLX3 DLX2 NR1I3 OASL RNF4 DLX6 AIRE RAD54B TCF19 RBPJ ZFHX3 KLF1 TCF15 EVX1 TBX22 TBX21 CCNT1 PPARG MLH1 NFKB1 MLH3 TERF2IP NFKB2 ZEB1 GLI2 GLI3 PMS2P1 CDT1 KCNIP3 GLI1 ZBTB38 FANCG TOP2A MSL3 NR2F1 ZBTB22 SNAPC5 SNAPC2 SNAPC4 SNAPC3 APTX MBD4 MBD3 RAD52 MBD2 MBD1 RAD50 ZBTB25 RAD51 HNRPDL SLC26A3 EHF ZBTB17 KIN POLR2B MLF1 STAT6 ZFP36L2 STAT4 XBP1 ETV1 MLLT1 AATF BCL6 ETV6 ETV5 PDS5B TBX3 TBX2 HCLS1 TBX5 TBX4 AFF4 TBX1 ILF3 AFF1 STAT1 MSRB2 STAT3 ILF2 NEUROD2 CIR1 HNRNPAB MYOD1 THRA ARNT2 FOXO1 ANKRD1 FOXO3 FOXO4 TLR8 GATA1 TOP1 GATA2 ATOH1 CGGBP1 GATA3 TARDBP HOXC5 RC3H2 GABPB2 RBMS1 CIITA SATB1 POU5F1B ZNF189 FOXN2 NR0B1 TRERF1 SP140 AHR ZNF197 MYNN TFAP4 SOX3 SOX5 ELK1 SOX4 SP110 ELK3 RAD51B ALB CENPC1 HOXA7 RNF11 RAD51D ATF6B RUNX1 RUNX3 CREBL2 SREBF1 NFE2 ZMYM4 ZMYM3 PIF1 ZMYM6 GSC2 WRN FOXP3 BRCA1 GCM2 GCM1 PHF1 SALL1 RFX1 RFX3 MAFA RFX2 SCMH1 ZNF85 POU6F1 HIST4H4 AEBP1 POU6F2 NR6A1 FOXK2 BUD31 FUBP1 PCGF2 MCM7 POU5F1 PCBP1 PCGF6 POU4F3 POU4F2 POU4F1 TERT ALX1 ZW10 KHDRBS1 EGR1 ELP3 ELP2 EGR3 NANOG REV1 EGR2 SOX13 SOX14 RUNX1T1 DMRT1 DMRT2 LEF1 MCM2 MCM3 UBN1 MSC NUCB1 XPA XPC BPTF NUCB2 C1D ING2 MGMT NFIX POU1F1 RPA4 RPA3 RPA1 RPA2 NPAS1 NPAS2 ERCC5 ERCC6 HAND1 HAND2 SAFB POU2F2 POU2F1 NFAT5 POU3F4 POU3F3 MYOG POU3F2 POU3F1 TINF2 APEX1 ERCC4 ERCC1 ENO1 ZBTB7A MSH6 FOXL2 FOXL1 RAD51AP1 MSH3 MSH2 MSH4 IRF9 MPG SON SP1 MAP1S IRF8 ARHGAP35 PRM1 PRM2 NFIC NFIB | |
| UBIQUITIN_PROTEIN_LIGASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/UBIQUITIN_PROTEIN_LIGASE_ACTIVITY DZIP3 RNF217 MYLIP WWP2 WWP1 FBXO22 ANAPC2 ANAPC5 ANAPC4 UBR3 UBE2H UBE2C BRAP UHRF2 HUWE1 UBE2K UBR5 UBE2M DDB2 MDM2 FBXL6 AMFR ZER1 FBXL2 ANAPC10 UBE3C ANAPC11 STUB1 ERCC8 UBE2D3 UBE2D2 FBXW2 FBXO3 TRAF7 TRAF6 FBXO7 RNF144B FBXO2 CBL CDC23 UBE2L6 MALT1 PARK2 UBE2L3 TRIM23 BIRC3 SMURF2 SMURF1 UBE2E1 | |
| GALACTOSYLTRANSFERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GALACTOSYLTRANSFERASE_ACTIVITY B4GALT1 ITGA2B B4GALT3 B4GALT2 A4GALT B3GALT2 B3GALT5 B3GALT4 B3GALNT1 B3GNT6 UGT8 B4GALT6 B4GALT7 C1GALT1 B4GALT4 B4GALT5 | |
| CYCLASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CYCLASE_ACTIVITY GUCY2F ADCY9 ADCY7 ADCY8 RTCD1 GUCY1A2 GUCY1A3 GUCY1B3 GUCY2C ADCY10 GUCY2D | |
| SINGLE_STRANDED_RNA_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/SINGLE_STRANDED_RNA_BINDING ZFP36 ADARB2 PABPC4 TLR7 TLR8 HNRPDL ATXN1 EIF4A3 A1CF TIA1 PABPC3 PABPC1 HNRNPH1 | |
| GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY FGD2 ALS2 FGD1 PREX1 RCC1 RCBTB2 DOCK2 GBF1 TIAM2 RASGRP4 TIAM1 SOS1 RAPGEF6 RAPGEF5 RAPGEF4 RAPGEF3 EIF2B2 RAPGEF2 FGD5 EIF2B3 FGD6 EIF2B4 FGD4 EIF2B5 NET1 CYTH1 ARHGEF3 SERGEF ARHGEF2 CYTH2 ARHGEF1 CYTH3 MADD TRIO ARHGEF17 HERC1 PREX2 EIF2B1 FARP1 ARHGEF11 FARP2 ANKRD27 PLCE1 CYTH4 RAPGEFL1 KALRN | |
| ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY SLC9A7 ATP1B1 SLC9A6 ATP1B3 SLC9A5 ATP1B2 SLC9A3 SLC9A2 ATP2B1 ATP2B3 CUL5 ATP2B4 KCNK7 KCNK6 KCNK5 CHRNA4 CHRNA7 CHRNA6 CHRNA1 CHRNA3 CHRNA2 SLC12A7 CLCA2 CLCA1 SLC12A9 SCN2B CLCA4 ABCB11 SCN2A NNT ADAMTS8 RHCG ATP2C1 RYR3 RYR1 RYR2 SURF1 KCNMB3 CLCN1 KCNMB4 ORAI1 CLCN3 SCN1B CLCN2 CACNB1 CACNB2 CACNB3 CACNB4 KCNJ3 KCNMB1 KCNJ1 KCNMB2 SLC11A2 ATP6V0C SLC31A2 SLC31A1 TRPC1 TRPC4 TRPC3 TRPC5 KCNK1 KCNK3 KCNK4 KCNJ5 KCNJ4 KCNJ6 ATP2A2 ATP2A3 LASP1 ATP2A1 CHRNB4 CHRNB3 CHRND CHRNB2 CHRNE CLCN4 SLC9A1 KCNK17 KCNH1 KCNJ15 ATP6V0E1 KCNK15 COX11 GLRA1 SLC20A1 SLC15A1 COX10 TRPV1 SLC20A2 SLC15A2 TRPV2 GLRA2 GJA1 KCNJ10 KCNIP2 KCNJ12 HVCN1 KCNJ14 KCNK10 FXN NMUR2 TRPV5 SLC22A4 SLC25A3 SLC22A3 SLC22A6 TRPV6 SLC22A2 COX15 KCNG2 SLC22A1 ATP4A ATP4B SLC22A7 SLC22A8 SLC3A2 CACNG5 CACNG4 CYB5A CFTR CACNG2 CACNG1 STX1B SLC26A4 KCNA10 ATP6V1C1 BSND SCN11A KCNH2 KCNH3 KCNH4 CLDN16 SHROOM2 COX7A2L BEST1 PKD2 KCNE1 KCNE2 HTR3A HTR3B SLC8A1 COX7A1 ATP1A3 ATP1A4 ATP1A1 ATP1A2 ITPR3 TRAPPC10 ITPR1 ITPR2 ACCN1 ACCN4 ABCC3 ABCC2 ABCC8 ABCC5 KCNC1 KCNC4 KCNC3 SLC22A13 SLC6A2 SLC22A14 SLC22A11 CNGB1 COX5A COX5B MS4A2 SLC4A2 SLC4A1 SLC4A4 SLC4A3 KCND3 SLC34A1 CNGA3 SLC34A3 SLC34A2 SLC40A1 FXYD1 FXYD2 FXYD3 KCNA2 COX7B KCNA1 KCNA4 KCNA3 KCNA6 ATP6V1B2 KCNA5 KCNS3 KCNS1 GAR1 ZACN SLC30A4 SCN9A SLC30A5 SLC30A3 CACNA2D1 KCNB2 COX8A ANKH CACNA1S ATP7A P2RX5 P2RX4 SLC25A11 P2RX7 SLC4A11 P2RX1 P2RX3 P2RX2 CACNA1G SLC13A2 CACNA1H CACNA1E SLC13A4 CACNA1F ASNA1 CACNA1C CACNA1D CACNA1A ATP7B CACNA1B SLC5A3 SLC5A2 SLC5A5 UQCRC1 SLC5A1 KCNQ5 KCNQ3 CCT8L2 SCN7A KCNQ2 KCNQ1 TRPM5 COX4I2 COX4I1 TRPM2 TRPM1 UQCRH CLCNKA CLCNKB SLCO1A2 CCS SCNN1G SCNN1B SCN5A SLC39A2 SCNN1D PLP2 GLRB NOX5 SLC12A1 SLC12A2 SLC12A3 SLC12A4 NOX1 SLC10A2 RHAG SLC10A1 SLC17A7 SLCO1B3 KCNN4 SLC17A5 SLC6A9 SLC17A3 SLC6A8 SLC17A4 SLC17A1 KCNN3 SLC6A5 SLCO1B1 KCNN2 SLC6A6 SLC17A2 SCN4B SLC5A6 SLC5A7 SCN4A | |
| PHOSPHOLIPID_TRANSPORTER_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/PHOSPHOLIPID_TRANSPORTER_ACTIVITY PITPNM1 PLSCR1 CDIPT PITPNM3 PITPNA PCTP ATP11B ATP8B1 PITPNC1 CETP ABCA1 ABCG1 | |
| LOW_DENSITY_LIPOPROTEIN_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/LOW_DENSITY_LIPOPROTEIN_BINDING APOA4 CDH13 LDLR ANKRA2 STAB1 CXCL16 SORL1 LRP6 COLEC12 STAB2 SCARF1 VLDLR | |
| HORMONE_RECEPTOR_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/HORMONE_RECEPTOR_BINDING MMS19 MED24 DAXX SMARCD3 TRIP12 MED12 MED14 MED13 HMGA1 PPARGC1B TACC2 NRIP1 PRPF6 MED4 OASL MED30 YWHAH PSMC5 NUP62 MED16 MED17 NCOA6 THRAP3 TGFB1I1 JMJD1C DDX54 NSD1 MED1 ZNHIT3 | |
| CYTOKINE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CYTOKINE_ACTIVITY IL19 FGF10 CXCL11 CXCL12 TGFB2 CXCL10 IFNG SPRED2 ERAP1 IFNK SPRED1 YARS IL29 IL27 IL25 IL21 IL20 CD40LG VEGFA SDCBP SIVA1 CCL1 CCL3 CCL2 ERBB2 CCL8 CX3CL1 CCL5 CCL4 CCL7 IL17C IFNA2 IL17A IL17B IFNA7 IFNA5 IFNA4 IL17F CKLF AIMP1 IFNA8 BMP4 IL1RN MUC4 GH1 CXCL14 CXCL13 CXCL16 GLMN TRIP6 XCL1 XCL2 IFNA21 TNFRSF11B PRL INHA CDK5 OSM INHBB INHBA IL12A IL12B CXCL1 CSF3 CSF2 TNF CXCL5 CSF1 CXCL3 CTF1 C5 CXCL2 CXCL9 PF4 CXCL6 NAMPT CCL28 CCL27 CCL26 MIF CCL24 CCL25 TYMP CCL22 CCL23 CCL20 CCL21 FIGF PIK3R1 SCG2 IL4 SECTM1 IL3 IL5 IL8 IL7 CCL19 CCL16 CCL15 CCL18 CCL17 CCL11 CCL13 CNTF ERBB2IP BRE IFNA14 IFNA13 IFNA16 GDF15 IL36RN IL2 IFNA17 | |
| ATP_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/ATP_BINDING SIK1 ZAK STK38 STK36 TTN DMPK BTK MAP3K6 NLRC4 MAP3K5 DHX38 DDX25 CLP1 WNK4 VPS4A TLK1 PRKACB TLK2 EIF2B2 TWF2 ABCB11 WNK1 PIM1 OLA1 WNK3 WNK2 MYH9 STK4 STK3 CDKL5 MARK1 SARS2 MARK2 MAP4K3 NVL MAP4K4 MAP4K5 RFC1 NME1 RFC2 SMARCA5 NEK6 ABCA7 STK11 STK17B MAP4K2 MAP4K1 MYO9B ABCA2 STK17A PXK ABCA4 ABCA3 IRAK3 DYRK3 DYRK2 STK38L GABARAPL2 ABCB8 EPB42 PIF1 TGFBR1 SPHK1 NIM1 ABCB1 OXSR1 ABCB7 ABCB6 ABCG2 TRNT1 ATP7A CDC42BPG CDC42BPA TNK1 ABL1 ATP7B PC CDC42BPB ABCF1 BCKDK ABCF2 ACVRL1 SEPHS1 NUAK2 PEX6 PINK1 MOV10L1 LATS1 LATS2 ACVR1B PEX1 SIK3 SRPK2 HSP90AA1 ACTA1 TPX2 TP53 PRKCI MINK1 CFTR DAPK2 DAPK3 NLRP1 NEK11 SRPK1 DAPK1 RAD51 EIF4A3 MAST1 SIK2 MAST2 ERN1 ERN2 DMC1 ACVR1 MKNK2 BRSK2 MKNK1 TRIB1 N4BP2 GALK1 ERCC6 DGKE SNRK CDK11A CDK11B TOR1A ABCD2 ABCD4 MSH6 PDS5B MSH2 NLK GSG2 SMC4 RPS6KA5 ICK RPS6KA4 TSSK1A GCK HSPA4L ABCC3 DGKZ PPP2R4 TSSK2 ABCC1 PGK1 BMPR1B TSSK4 ABCC8 TSSK3 ABCC5 TSSK6 PGK2 BMPR1A ABCC6 | |
| METALLOENDOPEPTIDASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/METALLOENDOPEPTIDASE_ACTIVITY SPG7 THOP1 KEL MMP9 MMP8 IDE RCE1 MMP28 MMP3 MMP2 MMP24 ECE2 MMP20 FAP PITRM1 MBTPS2 MMP17 MMP16 MMP15 MMP14 MMP13 MMP12 MMP11 MMP23B MEP1A PMPCA ADAMTS2 | |
| ISOMERASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ISOMERASE_ACTIVITY HSD3B2 PTGES3 HSD3B1 GNPDA1 PDIA3 GNE PDIA2 PDIA6 PGAM2 LSS PDIA5 DSE DCT TOP1 TPI1 MUT PTGIS GSTZ1 TOP2A EBP P4HB ERP29 BPGM PMM2 PMM1 GLCE PGM3 ERP44 PPIE PGM5 MPI PTGDS DDT PGM1 IDI1 | |
| GROWTH_FACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/GROWTH_FACTOR_ACTIVITY FGF6 FGF18 FGF7 FGF14 PGF FGF9 FGF17 GDF5 BTC FGF16 FGF11 JAG2 FGF10 FGF13 OSGIN1 FGF12 CSPG5 BDNF CLCF1 IL4 TDGF1 ERAP1 TGFA GDF9 PDGFC FGF1 FGF3 FGF4 NUDT6 INHA IL21 INHBA GRN SDCBP IL12B CSF3 CSF2 NDP CSF1 EGF THPO IL3 NTF4 IL5 IL7 IL1RN MSTN CLEC11A DKK1 EPGN GDF10 AREG TRIP6 IL36RN IL2 | |
| MAP_KINASE_KINASE_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/MAP_KINASE_KINASE_KINASE_ACTIVITY MAP3K7 MAP3K6 MAP3K5 MAP3K4 ZAK MAP3K3 MAP3K9 MAP3K10 MAP3K13 MAP3K11 | |
| CASPASE_REGULATOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/CASPASE_REGULATOR_ACTIVITY FOXL2 CARD8 AIFM3 TNFSF14 TPD52L1 BIRC5 XIAP TRIAP1 MAP3K5 NOD1 CASP8AP2 TNFAIP8 CASP1 CD27 | |
| EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT http://www.broadinstitute.org/gsea/msigdb/cards/EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT DSPP KAL1 COMP IMPG1 IMPG2 ACAN FBN2 LAMB1 TFPI2 OPTC COL4A4 MUC2 MATN3 COL4A2 EFEMP2 FBN1 MATN1 CHI3L1 MGP MEPE PRELP LAMA1 LAMA4 FBLN1 FBLN2 LAMC1 MFAP5 | |
| ANTIOXIDANT_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/ANTIOXIDANT_ACTIVITY PRDX4 PRDX2 SELS GPX2 APOA4 MGST3 GSR TXNDC2 EPX GPX4 IPCEF1 GPX3 TXNRD2 MPO GSTZ1 CYGB TXNRD1 CAT | |
| ENDONUCLEASE_ACTIVITY_GO_0016893 http://www.broadinstitute.org/gsea/msigdb/cards/ENDONUCLEASE_ACTIVITY_GO_0016893 RPP38 EXO1 DICER1 POP1 RPP30 DBR1 POP4 APEX1 RPP40 POP7 FEN1 | |
| TRANSCRIPTION_COFACTOR_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/TRANSCRIPTION_COFACTOR_ACTIVITY HIRA MED24 MED23 MXI1 MED21 RFXAP MED26 MED27 PQBP1 RARA TBPL1 PHOX2B PCBD1 RXRB RXRA YY1 MECP2 PPARGC1A PPARGC1B MTF1 ABT1 MED16 VGLL1 MNT TGIF1 TGFB1I1 PIAS1 KAT2A TFCP2L1 CRTC1 NFKBIB MYEF2 DRAP1 PIR MAML3 BCOR NR1H4 NR1H3 KLF7 UTF1 KLF12 SUB1 MAML1 MAML2 CREBBP RYBP PMF1 C19orf2 UBP1 TONSL NR1I3 NR1I2 JAZF1 NCOR1 NCOR2 ZBTB32 HTATIP2 COPS5 ELF3 TSG101 ZEB1 NFKB2 HSBP1 KCNIP3 HSF2 CREG1 HSF4 NR2F2 BRD8 NR2F1 BATF3 GMEB1 SF1 MXD1 MBD1 MXD4 JMY MED6 MED7 SLC26A3 MED4 PFDN5 ZNF136 NAB2 BRDT SIAH2 SRCAP NSD1 ZNF274 NMI SUFU NR1D1 TADA2A PEX14 TRIP11 TRIP13 TRIM28 TRIM24 TRIM22 YAF2 RBM14 CIR1 NR5A1 MMS19 MYOD1 THRB CBX4 RBFOX2 AIP HOXC6 CASP8AP2 SMARCD2 SMARCD3 SND1 SMARCD1 TFB2M CIITA BCL10 ZNF593 POU2AF1 GABPA RELB HES6 NR0B2 CSDA JUNB DDIT3 EP300 SMARCE1 TRIM32 RIPK3 TFAP2B TFAP2A EDF1 NFE2L1 NFE2L3 SMARCA2 SMARCA4 EID1 TFAP4 TRRAP ELK3 NR2C2 ARNT ATF2 TCERG1 MEIS2 ELK4 TFEC NPM1 TFDP2 TAF9 SKIL RNF14 TFDP1 SSX1 TAF4 NFE2 TRIP4 EPAS1 HTT TAF7 SAP18 GTF2A1L SNW1 ATF6 ATF5 PSMC5 ATF3 PSMC3 DYRK1B SMARCC1 GTF2F1 SMARCC2 DDX54 E2F1 ZNF85 E2F6 PRRX1 CTCF PAWR FEV TMF1 MAX SAP30 PLRG1 GTF2A1 E4F1 MKL2 NFIL3 NRG1 ALX1 SOX10 LDB1 ZFX LDB2 ESR2 HMGA1 MSC PRPF6 NRIP1 ZMIZ2 NCOA6 HIPK2 ZFPM2 CARM1 TDP2 NFYC TRIB3 HCFC1 HCFC2 CALCOCO1 ECD NFATC4 APEX1 ENO1 ERF DTX1 CREB1 PPP1R13L MED30 DR1 SP4 ARHGAP35 ID4 KAT2B IRF3 ID3 | |
| INOSITOL_OR_PHOSPHATIDYLINOSITOL_KINASE_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/INOSITOL_OR_PHOSPHATIDYLINOSITOL_KINASE_ACTIVITY PIK3CG PIKFYVE PIK3C2A PIK3CB PI4KA SMG1 ITPKB PI4KB ITPKA ATM FXN PI4K2A PIK3C3 PIK3CA PIK3R3 IPPK PIP4K2B PIK3R2 |