diff --git a/drivers/i2c/busses/i2c-tegra.c b/drivers/i2c/busses/i2c-tegra.c
index 15772964a05f1..3be101824e80a 100644
--- a/drivers/i2c/busses/i2c-tegra.c
+++ b/drivers/i2c/busses/i2c-tegra.c
@@ -1750,7 +1750,15 @@ static int tegra_i2c_probe(struct platform_device *pdev)
 		goto unprepare_slow_clk;
 	}
 
-	pm_runtime_irq_safe(&pdev->dev);
+	/*
+	 * VI I2C is in VE power domain which is not always on and not
+	 * an IRQ safe. So, IRQ safe device can't be attached to a non-IRQ
+	 * safe domain as it prevents powering off the PM domain.
+	 * Also, VI I2C device don't need to use runtime IRQ safe as it will
+	 * not be used for atomic transfers.
+	 */
+	if (!i2c_dev->is_vi)
+		pm_runtime_irq_safe(&pdev->dev);
 	pm_runtime_enable(&pdev->dev);
 	if (!pm_runtime_enabled(&pdev->dev)) {
 		ret = tegra_i2c_runtime_resume(&pdev->dev);