diff --git a/docs/tutorials/005_coexpression_networks_clusters.md b/docs/tutorials/005_coexpression_networks_clusters.md index 429a82f..2c33bbb 100644 --- a/docs/tutorials/005_coexpression_networks_clusters.md +++ b/docs/tutorials/005_coexpression_networks_clusters.md @@ -1,5 +1,28 @@ # Tutorial: Coexpression Networks and Clusters -## Navigating Coexpression Networks +## Coexpression intro + +Genes which display a similar expression profile across many samples are considered co-expressed. As co-expression is +often attributed to a shared regulatory mechanism, co-expressed genes are likely to be involved in the same biological +process. + +![Coexpression example](images/coexpression_example.png "Coexpression Example") + +In the example two profiles of co-expressed genes are show, the strength of their co-expression is indicated by the +[Pearson Correlation Coefficient](https://en.wikipedia.org/wiki/Pearson_correlation_coefficient) (PCC) which is +determined taking all samples into account (not just the ones included inthe profile) + + +## Navigating Coexpression Neighborhoods + +A gene's coexpressed genes (referred to as the coexpression neighborhood) can be found on the sequence page. + +![Coexpression entry(images/coexpression_entry.png "Coexpression Entry") + + The table icon ![table icon](images/table_icon.png "table icon") can be used to access a table with details on all + coexpressed genes. The network icon ![network icon](images/network_icon.png "network icon") lead to a network graph + visualized using [Cytoscape.js](http://js.cytoscape.org/) of the gene and its coexpression neighborhood. + + ## Coexpression Clusters \ No newline at end of file diff --git a/docs/tutorials/images/coexpression_entry.png b/docs/tutorials/images/coexpression_entry.png new file mode 100644 index 0000000..fc0f07f Binary files /dev/null and b/docs/tutorials/images/coexpression_entry.png differ diff --git a/docs/tutorials/images/coexpression_example.png b/docs/tutorials/images/coexpression_example.png new file mode 100644 index 0000000..ee7e680 Binary files /dev/null and b/docs/tutorials/images/coexpression_example.png differ