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README: parameter update
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renewiegandt committed Jan 18, 2019
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Expand Up @@ -62,14 +62,17 @@ Required arguments:
--config Path to UROPA configuration file
--organism Input organism [hg38 | hg19 | mm9 | mm10]
--out Output Directory (Default: './out/')
[
--create_known_tfbs_path Path to directory where output from tfbsscan (known motifs) are stored.
Path can be set as tfbs_path in next run. (Needs absolute path)
or
--tfbs_path Path to directory with output from tfbsscan. If given tfbsscan will not be run. (Needs absolute path)
]
Optional arguments:
--help [0|1] 1 to show this help message. (Default: 0)
--tfbs_path Path to directory with output from tfbsscan. If given tfbsscan will not be run.
--create_known_tfbs_path Path to directory where output from tfbsscan (known motifs) are stored.
Path can be set as tfbs_path in next run. (Default: './')
--gtf_path Path to gtf-file. If path is set the process which creats a gtf-file is skipped.
--gtf_path Path to gtf-file. If path is set the process which creats a gtf-file is skipped.
Footprint extraction:
--window_length INT This parameter sets the length of a sliding window. (Default: 200)
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--iteration INT Number of iterations done by GLAM2. More Iterations: better results, higher runtime. (Default: 10000)
--tomtom_treshold FLOAT Threshold for similarity score. (Default: 0.01)
--best_motif INT Get the best X motifs per cluster. (Default: 3)
--gap_penalty INT Set penalty for gaps in GLAM2 (Default: 1000)
Moitf clustering:
--cluster_motif Boolean If 1 pipeline clusters motifs. If its 0 it does not. (Default: 0)
--cluster_motif Boolean If 1 pipeline clusters motifs. If its 0 it does not. (Defaul: 0)
--edge_weight INT Minimum weight of edges in motif-cluster-graph (Default: 5)
--motif_similarity_thresh FLOAT Threshold for motif similarity score (Default: 0.00001)
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