This repository provides analysis for the codon usage results in the following study:
Alvarez-Castelao, B., tom Dieck, S., Fusco, C.M., Donlin-Asp, P.G., Perez, J.D., and Schuman, E.M. (2020) The switch-like expression of Heme-regulated kinase 1 mediates neuronal proteostasis following proteasome inhibition. eLife, in press.
HRI uses more rare codons than the 86.78% of the genes expressed in the brain (see publication methods for more details).