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fix pablo.js doesn't support names with dash unless in quotes
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#### Adding coexpression network | ||
# Adding co-expression data and clusters | ||
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*UNDER CONSTRUCTION* | ||
## Adding co-expression network | ||
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#### Adding coexpression clusters | ||
Coexpression networks from [LSTrAP](https://github.molgen.mpg.de/proost/LSTrAP/) (Pearson Correlation based) can be directly imported | ||
and are converted to a rank-based network upon importing the file. | ||
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*UNDER CONSTRUCTION* | ||
In the admin menu select 'Add' -> 'Add Co-Expression Network'. | ||
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 | ||
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**Select the species first** and enter a suitable **description**. Next select a | ||
**Limit**, this specifies the maximum rank to keep. Lower values will retain fewer, | ||
but more reliable links where higher values result in a denser network. | ||
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A **PCC-cutoff** can be combined with the rank based cutoff. Turn this to -2 to | ||
disable the filter. | ||
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For sparse networks, a gene's neighborhood can be extended from direct neighbors | ||
only to include neighbors of neighbors (aka the second level). If you wish to do | ||
so tick the checkbox **Enable Second Level Neighborhood?**. WARNING: Enabling this | ||
option for dense networks will significantly impact the performance of several of | ||
CoNekT's features. | ||
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Finally the full expression table as generated by LSTrAP should be selected. Click | ||
**"Add Network"** to upload the file (note files can be large, this step can take a | ||
while) and import the data into the database. | ||
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## Adding co-expression clusters | ||
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Co-expression clusters can either be imported or generated using a built-in | ||
clustering algorithm (Heuristic Cluster Chiseling Algorithm). | ||
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### Importing MCL Clusters | ||
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MCL based clusters (which are included in LSTrAP output) can be imported into LSTrAP. | ||
'Add' -> 'Coexpression Clusters' in the admin panel give you an interface where you | ||
can **select an existing network**, add a **description** for the new clusters and | ||
indicate a **minimal size** (to avoid including small clusters). Finally select the **MCL | ||
output** using **Select File** and click **Add Clusters** | ||
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 | ||
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### Building HCCA Clusters | ||
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Importing MCL clusters can have the disadvantage that the imported network is | ||
filtered differently and inconsistencies emerge between clusters and networks. To | ||
remedy this, CoNekT allows admins to cluster the imported network using the HCCA. | ||
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 | ||
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This is very straightforward, but can be time consuming. Make sure the webserver | ||
doesn't have a timeout (or use the build in one). | ||
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Select a network, add a description for the clusters and click **Build Clusters**. |
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